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BACTERIAL LIPOPOLYSACCHARIDE INDUCES DE-NOVO SYNTHESIS OF CYCLOOXYGENASE ACTIVITY IN FRESHLY ISOLATED HUMAN MONONUCLEAR-CELLS por Grossman, C, Trevethick, M, Wiseman, J, Bountra, C, Birch, P
Publicado em 1994Journal article -
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Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach. por Beswick, P, Blackaby, A, Bountra, C, Brown, T, Browning, K, Campbell, I, Corfield, J, Gleave, R, Guntrip, S, Hall, R, Hindley, S, Lambeth, P, Lucas, F, Mathews, N, Naylor, A, Player, H, Price, H, Sidebottom, P, Taylor, N, Webb, G, Wiseman, J
Publicado em 2009Journal article -
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The cyclooxygenase-2 inhibitor GW406381X [2-(4-ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] is effective in animal models of neuropathic pain and central s... por Bingham, S, Beswick, P, Bountra, C, Brown, T, Campbell, I, Chessell, I, Clayton, N, Collins, S, Davey, P, Goodland, H, Gray, N, Haslam, C, Hatcher, J, Hunter, A, Lucas, F, Murkitt, G, Naylor, A, Pickup, E, Sargent, B, Summerfield, S, Stevens, A, Stratton, S, Wiseman, J
Publicado em 2005Journal article -
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Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors. por Beswick, P, Bingham, S, Bountra, C, Brown, T, Browning, K, Campbell, I, Chessell, I, Clayton, N, Collins, S, Corfield, J, Guntrip, S, Haslam, C, Lambeth, P, Lucas, F, Mathews, N, Murkit, G, Naylor, A, Pegg, N, Pickup, E, Player, H, Price, H, Stevens, A, Stratton, S, Wiseman, J
Publicado em 2004Journal article