„Eine 95%-Wirksamkeit bedeutet eigentlich recht wenig“ by Prof. Dr. med. Wolf-Dieter Ludwig, Prof. Dr. Reinhold Roski, Peter Stegmaier

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Educating physicians on strong opioids by descriptive versus simulated-experience formats: a randomized controlled trial by Odette Wegwarth, Claudia Spies, Wolf-Dieter Ludwig, Norbert Donner-Banzhoff, Günther Jonitz, Ralph Hertwig

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NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia by Obul R. Bandapalli, Martin Zimmermann, Corinne Kox, Martin Stanulla, Martin Schrappe, Wolf-Dieter Ludwig, Rolf Koehler, Martina U. Muckenthaler, Andreas E. Kulozik

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A Patient with Non-Hodgkin Lymphoma and Nonspecific Interstitial Pneumonia during Ibrutinib Therapy by Sven Jungmann, Wolf-Dieter Ludwig, Nicolas Schönfeld, Torsten-Gerriet Blum, Claudia Großwendt, Christian Boch, Beate Rehbock, Sergej Griff, Alexander Schmittel, Torsten T. Bauer

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Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans’ cell sarcoma: evidence for hematopoietic plasticity by Richard Ratei, Michael Hummel, Ioannis Anagnostopoulos, Doris Jähne, Renate Arnold, Bernd Dörken, Stephan Mathas, Thomas Benter, Oliver Dudeck, Wolf-Dieter Ludwig, Harald Stein

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Experiencing the risk of overutilising opioids among patients with chronic non-cancer pain in ambulatory care (ERONA): the protocol of an exploratory, randomised controlled trial by Odette Wegwarth, Joerg J Meerpohl, Norbert Donner-Banzhoff, Claudia Spies, Christine Schmucker, Erika Schulte, Edris Nury, Dirk Brockmann, Stefan Wind, Eva Goebel, Wolf-Dieter Ludwig, Ralph Hertwig

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Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia by Leonid Karawajew, Michael Dworzak, Richard Ratei, Peter Rhein, Giuseppe Gaipa, Barbara Buldini, Giuseppe Basso, Ondrej Hrusak, Wolf-Dieter Ludwig, Günter Henze, Karl Seeger, Arend von Stackelberg, Ester Mejstrikova, Cornelia Eckert

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High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol by Gunnar Cario, Peter Rhein, Rita Mitlöhner, Martin Zimmermann, Obul R. Bandapalli, Renja Romey, Anja Moericke, Wolf-Dieter Ludwig, Richard Ratei, Martina U. Muckenthaler, Andreas E. Kulozik, Martin Schrappe, Martin Stanulla, Leonid Karawajew

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Molecular characterization and clinical course of MLL-ACTN4 rearrangement in therapy-related hematologic malignancies by John Jeongseok Yang, Tae Sung Park, Seung-Tae Lee, Ja-Young Seo, Seung Hwan Oh, Eun Hae Cho, Thomas Burmeister, Wolf-Dieter Ludwig, Claus Meyer, Rolf Marschalek, Hee-Jin Kim, Sun-Hee Kim

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IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol by Petra Dörge, Barbara Meissner, Martin Zimmermann, Anja Möricke, André Schrauder, Jean-Pierre Bouquin, Denis Schewe, Jochen Harbott, Andrea Teigler-Schlegel, Richard Ratei, Wolf-Dieter Ludwig, Rolf Koehler, Claus R. Bartram, Martin Schrappe, Martin Stanulla, Gunnar Cario

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Genome wide molecular analysis of minimally differentiated acute myeloid leukemia by Fernando P.G. Silva, Inês Almeida, Bruno Morolli, Geeske Brouwer-Mandema, Hans Wessels, Rolf Vossen, Harry Vrieling, Erik W.A. Marijt, Peter J.M. Valk, Hanneke C. Kluin-Nelemans, Wolfgang R. Sperr, Wolf-Dieter Ludwig, Micheline Giphart-Gassler

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NOTCH1 mutation, TP53 alteration and myeloid antigen expression predict outcome heterogeneity in children with first relapse of T-cell acute lymphoblastic leukemia by Jana Hof, Corinne Kox, Stefanie Groeneveld-Krentz, Obul R. Bandapalli, Leonid Karawajew, Katharina Schedel, Joachim B. Kunz, Cornelia Eckert, Wolf-Dieter Ludwig, Richard Ratei, Peter Rhein, Günter Henze, Martina U. Muckenthaler, Andreas E. Kulozik, Arend von Stackelberg, Renate Kirschner-Schwabe

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Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual... by Lutz Zeidler, Martin Zimmermann, Anja Möricke, Barbara Meissner, Dorothee Bartels, Christoph Tschan, André Schrauder, Gunnar Cario, Lilia Goudeva, Sarah Jäger, Richard Ratei, Wolf-Dieter Ludwig, Andrea Teigler-Schlegel, Julia Skokowa, Rolf Koehler, Claus R. Bartram, Hansjörg Riehm, Martin Schrappe, Karl Welte, Martin Stanulla

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Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leuk... by Giuseppe Gaipa, Giovanni Cazzaniga, Maria Grazia Valsecchi, Renate Panzer-Grümayer, Barbara Buldini, Daniela Silvestri, Leonid Karawajew, Oscar Maglia, Richard Ratei, Alessandra Benetello, Simona Sala, Angela Schumich, Andre Schrauder, Tiziana Villa, Marinella Veltroni, Wolf-Dieter Ludwig, Valentino Conter, Martin Schrappe, Andrea Biondi, Michael N. Dworzak, Giuseppe Basso

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Acute Myeloid Leukemia (AML): The Role of Maintenance Chemo-therapy by Thomas Büchner, Wolfgang Hiddemann, Wolfgang E Berdel, Bernhard Wörmann, Helmut Löffler, Claudia Schoch, Torsten Haferlach, Wolf-Dieter Ludwig, Georg Maschmeyer, Eva Lengelder, Peter Staib, Reinhard Andreesen, Leopold Balleisen, Detlef Haase, Hartmut Eimermacher, Carlo Aul, Herbert Rasche, Jens Uhlig, Andreas Grüneisen, Hans Edgar Reis, Joachim Hartlapp, Wolf-Dietrich Hirschmann, Hans-Josef Weh, Hermann-Josef Pielken, Winfried Gassmann, Andrea Schumacher, Maria-Cristina Sauerland, Achim Heinecke

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Acute Myeloid Leukemia (AML): The Role of Intensive Induction Chemotherapy by Thomas Büchner, Wolfgang Hiddemann, Wolfgang E Berdel, Bernhard Wörmann, Helmut Löffler, Claudia Schoch, Torsten Haferlach, Wolf-Dieter Ludwig, Georg Maschmeyer, Eva Lengelder, Peter Staib, Reinhard Andreesen, Leopold Balleisen, Detlef Haase, Hartmut Eimermacher, Andrea Schumacher, Carlo Aul, Herbert Rasche, Jens Uhlig, Andreas Grüneisen, Hans Edgar Reis, Joachim Hartlapp, Wolf-Dietrich Hirschmann, Hans-Josef Weh, Hermann-Josef Pielken, Winfried Gassmann, Maria-Cristina Sauerland, Achim Heinecke

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Acute Myeloid Leukemia (AML): The Role of Intensive Induction Chemotherapy by Thomas Büchner, Wolfgang Hiddemann, Wolfgang E. Berdel, Bernhard Wörmann, Helmut Löffler, Claudia Schoch, Torsten Haferlach, Wolf-Dieter Ludwig, Georg Maschmeyer, Eva Lengelder, Peter Staib, Reinhard Andreesen, Leopold Balleisen, Detlef Haase, Hartmut Eimermacher, Andrea Schumacher, Carlo Aul, Herbert Rasche, Jens Uhlig, Andreas Grüneisen, Hans Edgar Reis, Joachim Hartlapp, Wolf-Dietrich Hirschmann, Hans-Josef Weh, Hermann-Josef Pielken, Winfried Gassmann, Maria-Cristina Sauerland, Achim Heinecke for the German AML Cooperative Group

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Acute Myeloid Leukemia (AML): The Role of Maintenance Chemo¬therapy by Thomas Büchner, Wolfgang Hiddemann, Wolfgang E. Berdel, Bernhard Wörmann, Helmut Löffler, Claudia Schoch, Torsten Haferlach, Wolf-Dieter Ludwig, Georg Maschmeyer, Eva Lengelder, Peter Staib, Reinhard Andreesen, Leopold Balleisen, Detlef Haase, Hartmut Eimermacher, Carlo Aul, Herbert Rasche, Jens Uhlig, Andreas Grüneisen, Hans Edgar Reis, Joachim Hartlapp, Wolf-Dietrich Hirschmann, Hans-Josef Weh, Hermann-Josef Pielken, Winfried Gassmann, Andrea Schumacher, Maria-Cristina Sauerland, Achim Heinecke for the German AML Cooperative Group

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