Early menopausal bone loss at the spine is associated with polymorphism at the interleukin 1 receptor antagonist locus di Keen, R, WoodfordRichens, K, Major, P, Lanchbury, J, Spector, T

Germline mutations in the TGF-beta and Wnt signalling pathways are a rare cause of the "multiple" adenoma phenotype. di Lipton, L, Sieber, O, Thomas, H, Hodgson, S, Tomlinson, I, Woodford-Richens, K

Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome. di Lampe, A, Hampton, P, Woodford-Richens, K, Tomlinson, I, Lawrence, C, Douglas, F

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway di Woodford-Richens, K, Rowan, A, Gorman, P, Halford, S, Bicknell, D, Wasan, H, Roylance, R, Bodmer, W, Tomlinson, I

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. di Woodford-Richens, K, Rowan, A, Gorman, P, Halford, S, Bicknell, D, Wasan, H, Roylance, R, Bodmer, W, Tomlinson, I

Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers. di Woodford-Richens, K, Rowan, A, Poulsom, R, Bevan, S, Salovaara, R, Aaltonen, L, Houlston, R, Wright, N, Tomlinson, I

CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers. di Woodford-Richens, K, Halford, S, Rowan, A, Bevan, S, Aaltonen, L, Wasan, H, Bicknell, D, Bodmer, W, Houlston, R, Tomlinson, I

CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers di Woodford-Richens, K, Halford, S, Rowan, A, Bevan, S, Aaltonen, L, Hasan, H, Bicknell, D, Bodmer, W, Houlston, R, Tomlinson, I

A family with juvenile polyposis linked to the BMPR1A locus: cryptic mutation or closely linked gene? di Chow, E, Lipton, L, Carvajal-Carmona, L, Arthur, G, Bhathal, P, Kaur, G, Jaeger, E, Woodford-Richens, K, Howarth, K, Tomlinson, I, Macrae, F

Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium. di Woodford-Richens, K, Williamson, J, Bevan, S, Young, J, Leggett, B, Frayling, I, Thway, Y, Hodgson, S, Kim, J, Iwama, T, Novelli, M, Sheer, D, Poulsom, R, Wright, N, Houlston, R, Tomlinson, I

Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome. di Bevan, S, Woodford-Richens, K, Rozen, P, Eng, C, Young, J, Dunlop, M, Neale, K, Phillips, R, Markie, D, Rodriguez-Bigas, M, Leggett, B, Sheridan, E, Hodgson, S, Iwama, T, Eccles, D, Bodmer, W, Houlston, R, Tomlinson, I

Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases. di Houlston, R, Bevan, S, Williams, A, Young, J, Dunlop, M, Rozen, P, Eng, C, Markie, D, Woodford-Richens, K, Rodriguez-Bigas, M, Leggett, B, Neale, K, Phillips, R, Sheridan, E, Hodgson, S, Iwama, T, Eccles, D, Bodmer, W, Tomlinson, I

An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome. di Jaeger, E, Woodford-Richens, K, Lockett, M, Rowan, A, Sawyer, E, Heinimann, K, Rozen, P, Murday, V, Whitelaw, S, Ginsberg, A, Atkin, W, Lynch, H, Southey, M, Debinski, H, Eng, C, Bodmer, W, Talbot, I, Hodgson, S, Thomas, H, Tomlinson, I

Analysis of genetic and phenotypic heterogeneity in juvenile polyposis. di Woodford-Richens, K, Bevan, S, Churchman, M, Dowling, B, Jones, D, Norbury, C, Hodgson, S, Desai, D, Neale, K, Phillips, R, Young, J, Leggett, B, Dunlop, M, Rozen, P, Eng, C, Markie, D, Rodriguez-Bigas, M, Sheridan, E, Iwama, T, Eccles, D, Smith, G, Kim, J, Kim, K, Sampson, JR, Evans, G

Germline mutations in BMPR1A/ALK3 cause a subset of cases of Juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes di Zhou, X, Woodford-Richens, K, Lehtonen, R, Kurose, K, Aldred, M, Hampel, H, Launonen, V, Virta, S, Pilarski, R, Salovaara, R, Bodmer, W, Conrad, B, Dunlop, M, Hodgson, S, Iwama, T, Järvinen, H, Kellokumpu, I, Kim, J, Leggett, B, Markie, D, Mecklin, J, Neale, K, Phillips, R, Piris, J, Rozen, P

Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. di Zhou, X, Woodford-Richens, K, Lehtonen, R, Kurose, K, Aldred, M, Hampel, H, Launonen, V, Virta, S, Pilarski, R, Salovaara, R, Bodmer, W, Conrad, B, Dunlop, M, Hodgson, S, Iwama, T, Järvinen, H, Kellokumpu, I, Kim, J, Leggett, B, Markie, D, Mecklin, J, Neale, K, Phillips, R, Piris, J, Rozen, P

Analysis of genetic and phenotypic heterogeneity in juvenile polyposis di Woodford-Richens, K, Tomlinson, P, Bevan, S, Houlston, R, Churchman, M, Dowling, B, Jones, D, Norbury, C, Hodgson, S, Desai, D, Neale, K, Phillips, R, Young, J, Leggett, B, Dunlop, M, Rozen, P, Eng, C, Markie, D, Rodriguez-Bigas, M, Sheridan, E, Iwama, T, Eccles, D, Smith, G, Kim, J, Kim, K