In vivo and in vitro activities and ADME-Tox profile of a quinolizidine-modified 4-aminoquinoline: A potent Anti-P. falciparum and anti-P. vivax blood-stage antimalarial by Basilico, N, Parapini, S, Sparatore, A, Romeo, S, Misiano, P, Vivas, L, Yardley, V, Croft, S, Habluetzel, A, Lucantoni, L, Renia, L, Russell, B, Suwanarusk, R, Nosten, F, Dondio, G, Bigogno, C, Jabes, D, Taramelli, D