Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase. by Zhou, L, McMahon, C, Bhagat, T, Alencar, C, Yu, Y, Fazzari, M, Sohal, D, Heuck, C, Gundabolu, K, Ng, C, Mo, Y, Shen, W, Wickrema, A, Kong, G, Friedman, E, Sokol, L, Mantzaris, I, Mantzaris, G, Pellagatti, A, Boultwood, J, Platanias, L, Steidl, U, Yan, L, Yingling, J, Lahn, M