Impact of preexisting proteinuria on the development of regorafenib-induced problematic proteinuria in real-world metastatic colorectal cancer treatment by Yoshitaka Saito, Yoh Takekuma, Yoshito Komatsu, Mitsuru Sugawara

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Hypertriglyceridemia Induced by Fluorouracil: A Novel Case Report by Yoshitaka Saito, Yoh Takekuma, Satoshi Yuki, Yoshito Komatsu, Mitsuru Sugawara

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Anti-epidermal growth factor receptor treatment for patients with Neo wild-type metastatic colorectal cancer: a case report of two cases by Kazuaki Harada, Satoshi Yuki, Yasuyuki Kawamoto, Takeaki Nakamura, Shiho Kaneko, Koichi Ishida, Naoya Sakamoto, Yoshito Komatsu

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Decreased RNA-binding motif 5 expression is associated with tumor progression in gastric cancer by Takahiko Kobayashi, Junich Ishida, Yuichi Shimizu, Hiroshi Kawakami, Goki Suda, Tetsuhito Muranaka, Yoshito Komatsu, Masahiro Asaka, Naoya Sakamoto

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Re‐appraisal of the universal definition of tumor rupture among patients with high‐risk gastrointestinal stromal tumors by Naoto Gotohda, Toshirou Nishida, Shinsuke Sato, Masato Ozaka, Yujiro Nakahara, Yoshito Komatsu, Masato Kondo, Haruhiko Cho, Yukinori Kurokawa, Yuko Kitagawa

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Characteristics and usefulness of transabdominal ultrasonography in immune-mediated colitis by Kensuke Sakurai, Takehiko Katsurada, Mutsumi Nishida, Satomi Omotehara, Shinya Fukushima, Shinsuke Otagiri, Kazunori Nagashima, Reizo Onishi, Ryo Takagi, Yoshito Komatsu, Naoya Sakamoto

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Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy by Kazuaki Harada, Wataru Okamoto, Sachiyo Mimaki, Yasuyuki Kawamoto, Hideaki Bando, Riu Yamashita, Satoshi Yuki, Takayuki Yoshino, Yoshito Komatsu, Atsushi Ohtsu, Naoya Sakamoto, Katsuya Tsuchihara

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The survival benefit of increasing the number of active drugs for metastatic colorectal cancer: A multicenter retrospective study by Takeshi Kawakami, Toshiki Masuishi, Yasuyuki Kawamoto, Hirofumi Go, Kyoko Kato, Ryosuke Kumanishi, Kentaro Sawada, Satoshi Yuki, Kouji Yamamoto, Yoshito Komatsu, Kei Muro, Kunihiro Fushiki, Hiromichi Shirasu, Kentaro Yamazaki

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An Investigator-Initiated Phase 2 Study of Nivolumab Plus Low-Dose Ipilimumab as First-Line Therapy for Microsatellite Instability—High Advanced Gastric or Esophagogastric Junction... by Hisato Kawakami, Shuichi Hironaka, Taito Esaki, Kazuaki Chayama, Masahiro Tsuda, Naotoshi Sugimoto, Shigenori Kadowaki, Akitaka Makiyama, Nozomu Machida, Hidekazu Hirano, Kenro Hirata, Hiroki Hara, Hiroshi Yabusaki, Yoshito Komatsu, Kei Muro

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Impact of tumour growth rate during preceding treatment on tumour response to regorafenib or trifluridine/tipiracil in refractory metastatic colorectal cancer by Toshiki Masuishi, Hiroya Taniguchi, Yoshito Komatsu, Takeshi Kawakami, Yasuyuki Kawamoto, Shigenori Kadowaki, Yusuke Onozawa, Tetsuhito Muranaka, Masahiro Tajika, Hirofumi Yasui, Hiroshi Nakatsumi, Satoshi Yuki, Kei Muro, Katsuhiro Omae, Kentaro Yamazaki

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of the afucosylated, humanized anti-EPHA2 antibody DS-8895a: a first-in-human phase I dose escalation and dose expansio... by Kohei Shitara, Taroh Satoh, Satoru Iwasa, Kensei Yamaguchi, Kei Muro, Yoshito Komatsu, Tomohiro Nishina, Taito Esaki, Jun Hasegawa, Yasuyuki Kakurai, Emi Kamiyama, Tomoko Nakata, Kota Nakamura, Hayato Sakaki, Ichinosuke Hyodo

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CA125 Kinetics as a Potential Biomarker for Peritoneal Metastasis Progression following Taxane-Plus-Ramucirumab Administration in Patients with Advanced Gastric Cancer by Akira Ueda, Satoshi Yuki, Takayuki Ando, Ayumu Hosokawa, Naokatsu Nakada, Yosuke Kito, Iori Motoo, Ken Ito, Miho Sakumura, Yurika Nakayama, Yuko Ueda, Shinya Kajiura, Koji Nakashima, Kazuaki Harada, Yasuyuki Kawamoto, Yoshito Komatsu, Ichiro Yasuda

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Correlation of <i>UGT1A1</i> Gene Polymorphisms or Prior Irinotecan Treatment and Treatment Outcomes of Nanoliposomal-Irinotecan plus 5-Fluorouracil/Leucovorin for Pancreatic Ducta... by Kazuaki Harada, Takahiro Yamamura, Osamu Muto, Michio Nakamura, Susumu Sogabe, Kentaro Sawada, Shintaro Nakano, Masataka Yagisawa, Tetsuhito Muranaka, Masayoshi Dazai, Miki Tateyama, Yoshimitsu Kobayashi, Sosuke Kato, Kazuteru Hatanaka, Yasuyuki Kawamoto, Satoshi Yuki, Yuh Sakata, Naoya Sakamoto, Yoshito Komatsu

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Feasibility of edoxaban for asymptomatic cancer-associated thrombosis in Japanese patients with gastrointestinal cancer: ExCAVE study by Michio Nakamura, Atsushi Ishiguro, Masayoshi Dazai, Yasuyuki Kawamoto, Satoshi Yuki, Susumu Sogabe, Ayumu Hosokawa, Kentaro Sawada, Osamu Muto, Naoki Izawa, Koji Nakashima, Yoshiki Horie, Masataka Yagisawa, Shinya Kajiura, Takayuki Ando, Yosuke Mitsuhashi, Yu Sunakawa, Yasuka Kikuchi, Yoshito Komatsu

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Study protocol of HGCSG1404 SNOW study: a phase I/II trial of combined chemotherapy of S-1, nab-paclitaxel and oxaliplatin administered biweekly to patients with advanced gastric c... by Yasuyuki Kawamoto, Yoshito Komatsu, Satoshi Yuki, Kentaro Sawada, Tetsuhito Muranaka, Kazuaki Harada, Hiroshi Nakatsumi, Hiraku Fukushima, Atsushi Ishiguro, Masayoshi Dazai, Kazuteru Hatanaka, Michio Nakamura, Ichiro Iwanaga, Minoru Uebayashi, Susumu Sogabe, Yoshimitsu Kobayashi, Takuto Miyagishima, Kota Ono, Naoya Sakamoto, Yuh Sakata

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Rationale and design of the BRAVERY study (EPOC1701): a multicentre phase II study of eribulin in patients with BRAF V600E mutant metastatic colorectal cancer by Hideaki Bando, Atsushi Ohtsu, Takayuki Yoshino, Toshiki Masuishi, Hiroya Taniguchi, Daisuke Kotani, Yoshito Komatsu, Eiji Shinozaki, Takako Eguchi Nakajima, Taroh Satoh, Tomohiro Nishina, Taito Esaki, Masashi Wakabayashi, Shogo Nomura, Koji Takahashi, Hiromi Ono, Nami Hirano, Noriko Fujishiro, Nozomu Fuse, Akihiro Sato

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A randomized, double‐blind, phase II study of oral histone deacetylase inhibitor resminostat plus S‐1 versus placebo plus S‐1 in biliary tract cancers previously treated with gemci... by Makoto Ueno, Chigusa Morizane, Masayuki Furukawa, Daisuke Sakai, Yoshito Komatsu, Yousuke Nakai, Masahiro Tsuda, Masato Ozaka, Nobumasa Mizuno, Manabu Muto, Akira Fukutomi, Masafumi Ikeda, Akihito Tsuji, Akio Katanuma, Toshikazu Moriwaki, Takeshi Kajiwara, Hiroshi Ishii, Yuji Negoro, Satoshi Shimizu, Noriko Nemoto, Shingo Kobayashi, Keigo Makino, Junji Furuse

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Study protocol for HGCSG1801: A multicenter, prospective, phase II trial of second-line FOLFIRI plus aflibercept in patients with metastatic colorectal cancer refractory to anti-EG... by Hiroshi Nakatsumi, Yoshito Komatsu, Tetsuhito Muranaka, Satoshi Yuki, Yasuyuki Kawamoto, Kazuaki Harada, Masayoshi Dazai, Miki Tateyama, Yusuke Sasaki, Takuto Miyagishima, Yasushi Tsuji, Masaki Katagiri, Michio Nakamura, Susumu Sogabe, Kazuteru Hatanaka, Takashi Meguro, Tomoe Kobayashi, Atsushi Ishiguro, Osamu Muto, Yoshiaki Shindo, Masahito Kotaka, Takayuki Ando, Ryo Takagi, Naoya Sakamoto, Yu Sakata

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Fecal microbiota in patients with a stoma decreases anaerobic bacteria and alters taxonomic and functional diversities by Shunsuke A. Sakai, Shunsuke A. Sakai, Masato Aoshima, Masato Aoshima, Kentaro Sawada, Satoshi Horasawa, Ayumu Yoshikawa, Takao Fujisawa, Shigenori Kadowaki, Tadamichi Denda, Nobuhisa Matsuhashi, Hisateru Yasui, Masahiro Goto, Kentaro Yamazaki, Yoshito Komatsu, Ryota Nakanishi, Yoshiaki Nakamura, Yoshiaki Nakamura, Hideaki Bando, Hideaki Bando, Yamato Hamaya, Yamato Hamaya, Shun-Ichiro Kageyama, Takayuki Yoshino, Katsuya Tsuchihara, Katsuya Tsuchihara, Riu Yamashita, Riu Yamashita

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Characteristics of anal canal cancer in Japan by Kazutaka Yamada, Yasumitsu Saiki, Koji Komori, Akio Shiomi, Masashi Ueno, Masaaki Ito, Koya Hida, Seiichiro Yamamoto, Manabu Shiozawa, Soichiro Ishihara, Yukihide Kanemitsu, Hideki Ueno, Tatsuya Kinjo, Kotaro Maeda, Junichiro Kawamura, Fumihiko Fujita, Keiichi Takahashi, Tsunekazu Mizushima, Yasuhiro Shimada, Shin Sasaki, Eiji Sunami, Fumio Ishida, Keiji Hirata, Shinobu Ohnuma, Kimihiko Funahashi, Jun Watanabe, Yusuke Kinugasa, Shigeki Yamaguchi, Yojiro Hashiguchi, Masataka Ikeda, Takeshi Sudo, Yoshito Komatsu, Keiji Koda, Kazuhiro Sakamoto, Masazumi Okajima, Hideyuki Ishida, Yuichi Hisamatsu, Taiki Masuda, Shinichiro Mori, Kazuhito Minami, Seiji Hasegawa, Shungo Endo, Akinori Iwashita, Madoka Hamada, Yoichi Ajioka, Koichiro Usuku, Tokunori Ikeda, Kenichi Sugihara

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