Substrate reduction therapy for inborn errors of metabolism gan Yue, WW, Mackinnon, S, Arruda Bezerra, G

IDUA mutational profile and genotype-phenotype relationships in UK patients with Mucopolysaccharidosis I gan Ghosh, A, Mercer, J, Mackinnon, S, Yue, WW, Church, H, Beesley, CE, Broomfield, A, Jones, SA, Tylee, K

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis gan Montgomery, AB, Kopec, J, Shrestha, L, Thezenas, M-L, Burgess-Brown, NA, Fischer, R, Yue, WW, Venables, PJ

Structural basis for human mitochondrial tRNA maturation gan Meynier, V, Hardwick, SW, Catala, M, Roske, JJ, Oerum, S, Chirgadze, DY, Barraud, P, Yue, WW, Luisi, BF, Tisné, C

Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition gan Froese, DS, Kopec, JM, Rembeza, E, Bezerra, GA, Oberholzer, AE, Suormala, T, Lutz, S, Chalk, R, Borkowska, O, Baumgartner, MR, Yue, WW

Genetic, structural, and functional analysis of pathogenic variations causing methylmalonyl-CoA epimerase deficiency gan Heuberger, K, Bailey, HJ, Burda, P, Chaikuad, A, Krysztofinska, E, Suormala, T, Bürer, C, Lutz, S, Fowler, B, Froese, DS, Yue, WW, Baumgartner, MR

Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism gan Arruda Bezerra, G, Foster, WR, Bailey, HJ, Hicks, KG, Sauer, SW, Dimitrov, B, McCorvie, TJ, Okun, JG, Rutter, J, Kölker, S, Yue, WW

15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism. gan Abis, G, Charles, RL, Kopec, J, Yue, WW, Atkinson, RA, Bui, TTT, Lynham, S, Popova, S, Sun, Y-B, Fraternali, F, Eaton, P, Conte, MR

Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release gan Bailey, HJ, Arruda Bezerra, G, Marcero, JR, Padhi, S, Foster, WR, Rembeza, E, Roy, A, Bishop, DF, Desnick, RJ, Bulusu, G, Dailey, HA, Yue, WW

Fragment screening reveals starting points for rational design of galactokinase 1 inhibitors to treat classic galactosemia gan Mackinnon, SR, Krojer, T, Foster, WR, Diaz-Saez, L, Tang, M, Huber, KVM, von Delft, F, Lai, K, Brennan, PE, Arruda Bezerra, G, Yue, WW

RAC1 missense mutations in developmental disorders with diverse phenotypes gan Reijnders, MRF, Ansor, NM, Kousi, M, Yue, WW, Tan, PL, Clarkson, K, Clayton-Smith, J, Corning, K, Jones, JR, Lam, WWK, Mancini, GMS, Marcelis, C, Mohammed, S, Pfundt, R, Roifman, M, Cohn, R, Chitayat, D, Millard, TH, Katsanis, N, Brunner, HG, Banka, S

Expanding the genetic and phenotypic spectrum of branched‐chain amino acid transferase 2 (BCAT2) deficiency gan Knerr, I, Colombo, R, Urquhart, J, Morais, A, Merinero, B, Oyarzabal, A, Pérez, B, Jones, SA, Perveen, R, Preece, MA, Rogers, Y, Treacy, EP, Mayne, P, Zampino, G, Mackinnon, S, Wassmer, E, Yue, WW, Robinson, I, Rodríguez-Pombo, P, Olpin, SE, Banka, S