Editorial: Decoding immunologic complex systems in cancer: the cutting-edge technologies revolutionizing cancer immunology and immunotherapy by Hu Li, Jin Zhang, Jin Zhang, Jin Zhang, Yuin Han Loh, Yuin Han Loh, Yuin Han Loh, Yuin Han Loh, Daniel D. Billadeau, Daniel D. Billadeau

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Gene networks of fully connected triads with complete auto-activation enable multistability and stepwise stochastic transitions. by Philippe C Faucon, Keith Pardee, Roshan M Kumar, Hu Li, Yuin-Han Loh, Xiao Wang

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Global H3.3 dynamic deposition defines its bimodal role in cell fate transition by Hai-Tong Fang, Chadi A. EL Farran, Qiao Rui Xing, Li-Feng Zhang, Hu Li, Bing Lim, Yuin-Han Loh

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Integration-free induced pluripotent stem cells from three endangered Southeast Asian non-human primate species by Qiuye Bao, Nicole Liling Tay, Christina Yingyan Lim, Delia Hwee Hoon Chua, Su Keyau Kee, Mahesh Choolani, Yuin-Han Loh, Soon Chye Ng, Chou Chai

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Zfp322a Regulates mouse ES cell pluripotency and enhances reprogramming efficiency. by Hui Ma, Hui Min Ng, Xiuwen Teh, Hu Li, Yun Hwa Lee, Yew Mei Chong, Yuin Han Loh, James J Collins, Bo Feng, Henry Yang, Qiang Wu

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Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases by Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin-Han Loh, Omer An, Henry He Yang, Veerabrahma Pratap Seshachalam, Judice L. Y. Koh, Woon-Khiong Chan, Shi Yan Ng, Boon Seng Soh

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Novel live cell fluorescent probe for human-induced pluripotent stem cells highlights early reprogramming population by Sandhya Sriram, Nam-Young Kang, Subha Subramanian, Tannistha Nandi, Samydurai Sudhagar, Qiaorui Xing, Gerine Jin-Ling Tong, Allen Kuan-Liang Chen, Thekkeparambil Chandrabose Srijaya, Patrick Tan, Yuin-Han Loh, Young-Tae Chang, Shigeki Sugii

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Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells by Tong Ming Liu, Ege Deniz Yildirim, Pin Li, Hai Tong Fang, Vinitha Denslin, Vibhor Kumar, Yuin Han Loh, Eng Hin Lee, Simon M. Cool, Bin Tean Teh, James H. Hui, Bing Lim, Ng Shyh-Chang

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Npac Is A Co-factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse Embryonic Stem Cells by Sue Yu, Jia Li, Guanxu Ji, Zhen Long Ng, Jiamin Siew, Wan Ning Lo, Ying Ye, Yuan Yuan Chew, Yun Chau Long, Wensheng Zhang, Ernesto Guccione, Yuin Han Loh, Zhi-Hong Jiang, Henry Yang, Qiang Wu

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Multi-species single-cell transcriptomic analysis of ocular compartment regulons by Pradeep Gautam, Kiyofumi Hamashima, Ying Chen, Yingying Zeng, Bar Makovoz, Bhav Harshad Parikh, Hsin Yee Lee, Katherine Anne Lau, Xinyi Su, Raymond C. B. Wong, Woon-Khiong Chan, Hu Li, Timothy A. Blenkinsop, Yuin-Han Loh

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Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells by Jiangping He, Xiuling Fu, Meng Zhang, Fangfang He, Wenjuan Li, Mazid Md. Abdul, Jianguo Zhou, Li Sun, Chen Chang, Yuhao Li, He Liu, Kaixin Wu, Isaac A. Babarinde, Qiang Zhuang, Yuin-Han Loh, Jiekai Chen, Miguel A. Esteban, Andrew P. Hutchins

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Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis by Thach Tuan Pham, Anh Hong Le, Cong Phi Dang, Suet Yen Chong, Dang Vinh Do, Boya Peng, Migara Kavishka Jayasinghe, Hong Boon Ong, Dong Van Hoang, Roma Anne Louise, Yuin‐Han Loh, Han Wei Hou, Jiong‐Wei Wang, Minh TN Le

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RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming by Cheng-Xu Delon Toh, Jun-Wei Chan, Zheng-Shan Chong, Hao Fei Wang, Hong Chao Guo, Sandeep Satapathy, Dongrui Ma, Germaine Yen Lin Goh, Ekta Khattar, Lin Yang, Vinay Tergaonkar, Young-Tae Chang, James J. Collins, George Q. Daley, Keng Boon Wee, Chadi A. EL Farran, Hu Li, Yoon-Pin Lim, Frederic A. Bard, Yuin-Han Loh

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Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levelsResearch in context by Aoife Murray, Gillian Gough, Ana Cindrić, Frano Vučković, David Koschut, Vincenzo Borelli, Dražen J. Petrović, Ana Bekavac, Ante Plećaš, Valentina Hribljan, Reinhard Brunmeir, Julija Jurić, Maja Pučić-Baković, Anita Slana, Helena Deriš, Azra Frkatović, Jűrgen Groet, Niamh L. O’Brien, Hong Yu Chen, Yee Jie Yeap, Frederic Delom, Steven Havlicek, Luke Gammon, Sarah Hamburg, Carla Startin, Hana D’Souza, Dinko Mitrečić, Mijana Kero, Ljubica Odak, Božo Krušlin, Željka Krsnik, Ivica Kostović, Jia Nee Foo, Yuin-Han Loh, Norris Ray Dunn, Susana de la Luna, Tim Spector, Ingeborg Barišić, Michael S.C. Thomas, Andre Strydom, Claudio Franceschi, Gordan Lauc, Jasminka Krištić, Ivan Alić, Dean Nižetić

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