Long-term IGF-I exposure decreases autophagy and cell viability. by Alessandro Bitto, Chad Lerner, Claudio Torres, Michaela Roell, Marco Malaguti, Viviana Perez, Antonello Lorenzini, Silvana Hrelia, Yuji Ikeno, Michelle Elizabeth Matzko, Roger McCarter, Christian Sell

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Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? by Alex F Bokov, Neha Garg, Yuji Ikeno, Sachin Thakur, Nicolas Musi, Ralph A DeFronzo, Ning Zhang, Rebecca C Erickson, Jon Gelfond, Gene B Hubbard, Martin L Adamo, Arlan Richardson

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Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice by Kai Mao, Gabriela Farias Quipildor, Tahmineh Tabrizian, Ardijana Novaj, Fangxia Guan, Ryan O. Walters, Fabien Delahaye, Gene B. Hubbard, Yuji Ikeno, Keisuke Ejima, Peng Li, David B. Allison, Hossein Salimi-Moosavi, Pedro J. Beltran, Pinchas Cohen, Nir Barzilai, Derek M. Huffman

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A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues by Dominik Saul, Robyn Laura Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang, Nathan K. LeBrasseur, Robert J. Pignolo, Paul D. Robbins, Laura J. Niedernhofer, Yuji Ikeno, Diana Jurk, João F. Passos, LaTonya J. Hickson, Ailing Xue, David G. Monroe, Tamara Tchkonia, James L. Kirkland, Joshua N. Farr, Sundeep Khosla

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Local senolysis in aged mice only partially replicates the benefits of systemic senolysis by Joshua N. Farr, Dominik Saul, Madison L. Doolittle, Japneet Kaur, Jennifer L. Rowsey, Stephanie J. Vos, Mitchell N. Froemming, Anthony B. Lagnado, Yi Zhu, Megan Weivoda, Yuji Ikeno, Robert J. Pignolo, Laura J. Niedernhofer, Paul D. Robbins, Diana Jurk, João F. Passos, Nathan K. LeBrasseur, Tamara Tchkonia, James L. Kirkland, David G. Monroe, Sundeep Khosla

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