A double blind placebo controlled randomized trial of the effect of acute uric acid changes on inflammatory markers in humans: A pilot study. by Toshiko Tanaka, Yuri Milaneschi, Yongqing Zhang, Kevin G Becker, Linda Zukley, Luigi Ferrucci

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Psychosocial effects assocPsychosocial effects associated with highly pathogenic avian influenza (H5N1) in Nigeriaiated with highly pathogenic avian influenza (H5N1) in Nigeria by Chiara Rafanelli, Sara Gostoli, Yuri Milaneschi, Victoria Pam, Godman E. Jonah, Oludayo F. Fasina

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Metabolomics signatures of depression: the role of symptom profiles by Hilde de Kluiver, Rick Jansen, Brenda W. J. H. Penninx, Erik J. Giltay, Robert A. Schoevers, Yuri Milaneschi

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Immuno-metabolic depression: from concept to implementation by Brenda W.J.H. Penninx, Femke Lamers, Rick Jansen, Michael Berk, Golam M. Khandaker, Livia De Picker, Yuri Milaneschi

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An integrative study of five biological clocks in somatic and mental health by Rick Jansen, Laura KM Han, Josine E Verhoeven, Karolina A Aberg, Edwin CGJ van den Oord, Yuri Milaneschi, Brenda WJH Penninx

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Reconsidering the prognosis of major depressive disorder across diagnostic boundaries: full recovery is the exception rather than the rule by Judith Verduijn, Josine E. Verhoeven, Yuri Milaneschi, Robert A. Schoevers, Albert M. van Hemert, Aartjan T. F. Beekman, Brenda W. J. H. Penninx

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Lifestyle behaviours do not moderate the association between childhood maltreatment and comorbid depression and cardiometabolic disease in older adults: a meta-analysis by Olujolagbe Layinka, Camille Souama, Serena Defina, Vilte Baltramonaityte, Charlotte A. M. Cecil, Punit Shah, Yuri Milaneschi, Femke Lamers, Brenda W. J. H. Penninx, Esther Walton

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Lipid peroxidation and depressed mood in community-dwelling older men and women. by Yuri Milaneschi, Matteo Cesari, Eleanor M Simonsick, Nicole Vogelzangs, Alka M Kanaya, Kristine Yaffe, Paola Patrignani, Andrea Metti, Stephen B Kritchevsky, Marco Pahor, Luigi Ferrucci, Brenda W J H Penninx, Health ABC study

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Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes by Michael Dannemann, Yuri Milaneschi, Danat Yermakovich, Victoria Stiglbauer, Hanna Maria Kariis, Kristi Krebs, Manuel A. Friese, Christian Otte, Estonian Biobank Research Team, Kelli Lehto, Brenda W. J. H. Penninx, Janet Kelso, Stefan M. Gold

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Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort by Silvia Montanari, Rick Jansen, Daniela Schranner, Gabi Kastenmüller, Matthias Arnold, Delfina Janiri, Gabriele Sani, Sudeepa Bhattacharyya, Siamak Mahmoudian Dehkordi, Boadie W. Dunlop, A. John Rush, Brenda W. H. J. Penninx, Rima Kaddurah-Daouk, Yuri Milaneschi

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Obesity and atypical depression symptoms: findings from Mendelian randomization in two European cohorts by Giorgio Pistis, Yuri Milaneschi, Caroline L. Vandeleur, Aurélie M. Lasserre, Brenda W.J.H. Penninx, Femke Lamers, Dorret I. Boomsma, Jouke-Jan Hottenga, Pedro Marques-Vidal, Peter Vollenweider, Gérard Waeber, Jean-Michel Aubry, Martin Preisig, Zoltán Kutalik

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Associations of depression and regional brain structure across the adult lifespan: Pooled analyses of six population-based and two clinical cohort studies in the European Lifebrain... by Julia Binnewies, Laura Nawijn, Andreas M. Brandmaier, William F.C. Baaré, David Bartrés-Faz, Christian A. Drevon, Sandra Düzel, Anders M. Fjell, Laura K.M. Han, Ethan Knights, Ulman Lindenberger, Yuri Milaneschi, Athanasia M. Mowinckel, Lars Nyberg, Anna Plachti, Kathrine Skak Madsen, Cristina Solé-Padullés, Sana Suri, Kristine B. Walhovd, Enikő Zsoldos, Klaus P. Ebmeier, Brenda W.J.H. Penninx

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Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment: an individual participant data meta-analysis including over 200,000 participants by Camille Souama, Femke Lamers, Yuri Milaneschi, Christiaan H. Vinkers, Serena Defina, Linda Garvert, Frederike Stein, Tom Woofenden, Katharina Brosch, Udo Dannlowski, Henrike Galenkamp, Ron de Graaf, Vincent W. V. Jaddoe, Anja Lok, Bas B. van Rijn, Henry Völzke, Charlotte A. M. Cecil, Janine F. Felix, Hans J. Grabe, Tilo Kircher, Karim Lekadir, Margreet ten Have, Esther Walton, Brenda W. J. H. Penninx, on behalf of the EarlyCause consortium

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Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. by Karen Kapur, Toby Johnson, Noam D Beckmann, Joban Sehmi, Toshiko Tanaka, Zoltán Kutalik, Unnur Styrkarsdottir, Weihua Zhang, Diana Marek, Daniel F Gudbjartsson, Yuri Milaneschi, Hilma Holm, Angelo Diiorio, Dawn Waterworth, Yun Li, Andrew B Singleton, Unnur S Bjornsdottir, Gunnar Sigurdsson, Dena G Hernandez, Ranil Desilva, Paul Elliott, Gudmundur I Eyjolfsson, Jack M Guralnik, James Scott, Unnur Thorsteinsdottir, Stefania Bandinelli, John Chambers, Kari Stefansson, Gérard Waeber, Luigi Ferrucci, Jaspal S Kooner, Vincent Mooser, Peter Vollenweider, Jacques S Beckmann, Murielle Bochud, Sven Bergmann

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Identifying causative mechanisms linking early-life stress to psycho-cardio-metabolic multi-morbidity: The EarlyCause project. by Nicole Mariani, Alessandra Borsini, Charlotte A M Cecil, Janine F Felix, Sylvain Sebert, Annamaria Cattaneo, Esther Walton, Yuri Milaneschi, Guy Cochrane, Clara Amid, Jeena Rajan, Juliette Giacobbe, Yolanda Sanz, Ana Agustí, Tania Sorg, Yann Herault, Jouko Miettunen, Priyanka Parmar, Nadia Cattane, Vincent Jaddoe, Jyrki Lötjönen, Carme Buisan, Miguel A González Ballester, Gemma Piella, Josep L Gelpi, Femke Lamers, Brenda W J H Penninx, Henning Tiemeier, Malte von Tottleben, Rainer Thiel, Katharina F Heil, Marjo-Riitta Järvelin, Carmine Pariante, Isabelle M Mansuy, Karim Lekadir

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Brain change trajectories in healthy adults correlate with Alzheimer’s related genetic variation and memory decline across life by James M. Roe, Didac Vidal-Piñeiro, Øystein Sørensen, Håkon Grydeland, Esten H. Leonardsen, Olena Iakunchykova, Mengyu Pan, Athanasia Mowinckel, Marie Strømstad, Laura Nawijn, Yuri Milaneschi, Micael Andersson, Sara Pudas, Anne Cecilie Sjøli Bråthen, Jonas Kransberg, Emilie Sogn Falch, Knut Øverbye, Rogier A. Kievit, Klaus P. Ebmeier, Ulman Lindenberger, Paolo Ghisletta, Naiara Demnitz, Carl-Johan Boraxbekk, Christian A. Drevon, Alzheimer’s Disease Neuroimaging Initiative, the Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing, Brenda Penninx, Lars Bertram, Lars Nyberg, Kristine B. Walhovd, Anders M. Fjell, Yunpeng Wang

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Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling by Nicolien A. van Vliet, Maxime M. Bos, Carisha S. Thesing, Layal Chaker, Maik Pietzner, Evelyn Houtman, Matt J. Neville, Ruifang Li-Gao, Stella Trompet, Rima Mustafa, Fariba Ahmadizar, Marian Beekman, Mariska Bot, Kathrin Budde, Constantinos Christodoulides, Abbas Dehghan, Christian Delles, Paul Elliott, Marina Evangelou, He Gao, Mohsen Ghanbari, Antonius E. van Herwaarden, M. Arfan Ikram, Martin Jaeger, J. Wouter Jukema, Ibrahim Karaman, Fredrik Karpe, Margreet Kloppenburg, Jennifer M. T. A. Meessen, Ingrid Meulenbelt, Yuri Milaneschi, Simon P. Mooijaart, Dennis O. Mook-Kanamori, Mihai G. Netea, Romana T. Netea-Maier, Robin P. Peeters, Brenda W. J. H. Penninx, Naveed Sattar, P. Eline Slagboom, H. Eka D. Suchiman, Henry Völzke, Ko Willems van Dijk, Raymond Noordam, Diana van Heemst, BBMRI Metabolomics Consortium

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Potential Genetic Overlap Between Insomnia and Sleep Symptoms in Major Depressive Disorder: A Polygenic Risk Score Analysis by Lindsay M. Melhuish Beaupre, Lindsay M. Melhuish Beaupre, Arun K. Tiwari, Arun K. Tiwari, Vanessa F. Gonçalves, Vanessa F. Gonçalves, Vanessa F. Gonçalves, Clement C. Zai, Clement C. Zai, Clement C. Zai, Clement C. Zai, Victoria S. Marshe, Victoria S. Marshe, Cathryn M. Lewis, Cathryn M. Lewis, Nicholas G. Martin, Andrew M. McIntosh, Mark J. Adams, Bernhard T. Baune, Bernhard T. Baune, Bernhard T. Baune, Doug F. Levinson, Dorret I. Boomsma, Brenda W. J. H. Penninx, Gerome Breen, Gerome Breen, Steve Hamilton, Swapnil Awasthi, Stephan Ripke, Stephan Ripke, Stephan Ripke, Stephan Ripke, Lisa Jones, Ian Jones, Enda M. Byrne, Ian B. Hickie, James P. Potash, Jianxin Shi, Myrna M. Weissman, Myrna M. Weissman, Yuri Milaneschi, Stanley I. Shyn, Eco J. C. de Geus, Gonneke Willemsen, Gregory M. Brown, Gregory M. Brown, James L. Kennedy, James L. Kennedy, James L. Kennedy, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

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Corrigendum: Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: A polygenic risk score analysis by Lindsay M. Melhuish Beaupre, Lindsay M. Melhuish Beaupre, Arun K. Tiwari, Arun K. Tiwari, Vanessa F. Gonçalves, Vanessa F. Gonçalves, Vanessa F. Gonçalves, Clement C. Zai, Clement C. Zai, Clement C. Zai, Clement C. Zai, Victoria S. Marshe, Victoria S. Marshe, Cathryn M. Lewis, Cathryn M. Lewis, Nicholas G. Martin, Andrew M. McIntosh, Mark J. Adams, Bernhard T. Baune, Bernhard T. Baune, Bernhard T. Baune, Doug F. Levinson, Dorret I. Boomsma, Brenda W. J. H. Penninx, Gerome Breen, Gerome Breen, Steve Hamilton, Swapnil Awasthi, Stephan Ripke, Stephan Ripke, Stephan Ripke, Stephan Ripke, Lisa Jones, Ian Jones, Enda M. Byrne, Ian B. Hickie, James P. Potash, Jianxin Shi, Myrna M. Weissman, Myrna M. Weissman, Yuri Milaneschi, Stanley I. Shyn, Eco J. C. de Geus, Gonneke Willemsen, Gregory M. Brown, Gregory M. Brown, James L. Kennedy, James L. Kennedy, James L. Kennedy, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

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Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. by Momoko Horikoshi, Reedik Mӓgi, Martijn van de Bunt, Ida Surakka, Antti-Pekka Sarin, Anubha Mahajan, Letizia Marullo, Gudmar Thorleifsson, Sara Hӓgg, Jouke-Jan Hottenga, Claes Ladenvall, Janina S Ried, Thomas W Winkler, Sara M Willems, Natalia Pervjakova, Tõnu Esko, Marian Beekman, Christopher P Nelson, Christina Willenborg, Steven Wiltshire, Teresa Ferreira, Juan Fernandez, Kyle J Gaulton, Valgerdur Steinthorsdottir, Anders Hamsten, Patrik K E Magnusson, Gonneke Willemsen, Yuri Milaneschi, Neil R Robertson, Christopher J Groves, Amanda J Bennett, Terho Lehtimӓki, Jorma S Viikari, Johan Rung, Valeriya Lyssenko, Markus Perola, Iris M Heid, Christian Herder, Harald Grallert, Martina Müller-Nurasyid, Michael Roden, Elina Hypponen, Aaron Isaacs, Elisabeth M van Leeuwen, Lennart C Karssen, Evelin Mihailov, Jeanine J Houwing-Duistermaat, Anton J M de Craen, Joris Deelen, Aki S Havulinna, Matthew Blades, Christian Hengstenberg, Jeanette Erdmann, Heribert Schunkert, Jaakko Kaprio, Martin D Tobin, Nilesh J Samani, Lars Lind, Veikko Salomaa, Cecilia M Lindgren, P Eline Slagboom, Andres Metspalu, Cornelia M van Duijn, Johan G Eriksson, Annette Peters, Christian Gieger, Antti Jula, Leif Groop, Olli T Raitakari, Chris Power, Brenda W J H Penninx, Eco de Geus, Johannes H Smit, Dorret I Boomsma, Nancy L Pedersen, Erik Ingelsson, Unnur Thorsteinsdottir, Kari Stefansson, Samuli Ripatti, Inga Prokopenko, Mark I McCarthy, Andrew P Morris, ENGAGE Consortium

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