Inhibition of the TRIM24 bromodomain reactivates latent HIV-1 nork Riley M. Horvath, Zabrina L. Brumme, Ivan Sadowski

Testu osoa

Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products nork Khumoekae Richard, David E. Williams, E. Dilip de Silva, Mark A. Brockman, Zabrina L. Brumme, Raymond J. Andersen, Ian Tietjen

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Sociodemographic correlates of HIV drug resistance and access to drug resistance testing in British Columbia, Canada. nork Genevieve Rocheleau, Conrado Franco-Villalobos, Natalia Oliveira, Zabrina L Brumme, Melanie Rusch, Jeannie Shoveller, Chanson J Brumme, P Richard Harrigan

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Detection of HIV transmission hotspots in British Columbia, Canada: A novel framework for the prioritization and allocation of treatment and prevention resources nork Angela McLaughlin, Paul Sereda, Natalia Oliveira, Rolando Barrios, Chanson J. Brumme, Zabrina L. Brumme, Julio S.G. Montaner, Jeffrey B. Joy

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Rates and Correlates of Short Term Virologic Response among Treatment-Naïve HIV-Infected Children Initiating Antiretroviral Therapy in Ethiopia: A Multi-Center Prospective Cohort S... nork Birkneh Tilahun Tadesse, Adugna Chala, Jackson Mukonzo, Tolosssa Eticha Chaka, Sintayehu Tadesse, Eyasu Makonnen, Zabrina L. Brumme, Chanson J. Brumme, Eleni Aklillu

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T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics. nork Tomohiro Akahoshi, Hiroyuki Gatanaga, Nozomi Kuse, Takayuki Chikata, Madoka Koyanagi, Naoki Ishizuka, Chanson J Brumme, Hayato Murakoshi, Zabrina L Brumme, Shinichi Oka, Masafumi Takiguchi

Testu osoa

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences nork Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D. Walker, Yong Xiong, Zabrina L. Brumme, Mark A. Brockman, Takamasa Ueno

Testu osoa

HIV-1 subtype C Nef-mediated SERINC5 down-regulation significantly contributes to overall Nef activity nork Delon Naicker, Nelson Sonela, Steven W. Jin, Takalani Mulaudzi, Doty Ojwach, Tarylee Reddy, Mark A. Brockman, Zabrina L. Brumme, Thumbi Ndung’u, Jaclyn K. Mann

Testu osoa

HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy. nork Aniqa Shahid, Bradley R Jones, Julia S W Yang, Winnie Dong, Tawimas Shaipanich, Kathryn Donohoe, Chanson J Brumme, Jeffrey B Joy, Janice M Leung, Zabrina L Brumme

Testu osoa

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity nork Steven W. Jin, Nirmin Alsahafi, Xiaomei T. Kuang, Shayda A. Swann, Mako Toyoda, Heinrich Göttlinger, Bruce D. Walker, Takamasa Ueno, Andrés Finzi, Zabrina L. Brumme, Mark A. Brockman

Testu osoa

Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma. nork Jingyan Chen, Nadine Tibroni, Daniel Sauter, Johanna Galaski, Toshiyuki Miura, Galit Alter, Birthe Mueller, Claudia Haller, Bruce D Walker, Frank Kirchhoff, Zabrina L Brumme, Takamasa Ueno, Oliver T Fackler

Testu osoa

Rapid Detection of SARS-CoV-2 Variants of Concern, Including B.1.1.28/P.1, British Columbia, Canada nork Nancy Matic, Christopher F. Lowe, Gordon Ritchie, Aleksandra Stefanovic, Tanya Lawson, Willson Jang, Matthew Young, Winnie Dong, Zabrina L. Brumme, Chanson J. Brumme, Victor Leung, Marc G. Romney

Testu osoa

Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors nork Gisele Umviligihozo, Jaclyn K. Mann, Steven W. Jin, Francis M. Mwimanzi, Hua-Shiuan A. Hsieh, Hanwei Sudderuddin, Guinevere Q. Lee, Helen Byakwaga, Helen Byakwaga, Conrad Muzoora, Peter W. Hunt, Jeff N. Martin, Jessica E. Haberer, Jessica E. Haberer, Etienne Karita, Susan Allen, Eric Hunter, Eric Hunter, Zabrina L. Brumme, Zabrina L. Brumme, Mark A. Brockman, Mark A. Brockman, Mark A. Brockman

Testu osoa

No detectable differences in Nef-mediated downregulation of HLA-I and CD4 molecules among HIV-1 group M lineages circulating in Cameroon, where the pandemic originated nork Nelson Sonela, Nelson Sonela, Nelson Sonela, Jaclyn Mann, Celestin Godwe, Celestin Godwe, Oumarou H. Goni, Oumarou H. Goni, Mérime Tchakoute, Nathalie Nkoue, Tulio de Oliveira, Tulio de Oliveira, Mark A. Brockman, Mark A. Brockman, Mark A. Brockman, Zabrina L. Brumme, Zabrina L. Brumme, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Marcel Tongo

Testu osoa

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells. nork Hendrik Streeck, Zabrina L Brumme, Michael Anastario, Kristin W Cohen, Jonathan S Jolin, Angela Meier, Chanson J Brumme, Eric S Rosenberg, Galit Alter, Todd M Allen, Bruce D Walker, Marcus Altfeld

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Rapid HIV-1 Disease Progression in Individuals Infected with a Virus Adapted to Its Host Population. nork Jiro Katoh, Ai Kawana-Tachikawa, Akihisa Shimizu, Dayong Zhu, Chungyong Han, Hitomi Nakamura, Michiko Koga, Tadashi Kikuchi, Eisuke Adachi, Tomohiko Koibuchi, George F Gao, Zabrina L Brumme, Aikichi Iwamoto

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HIV-1 variants are archived throughout infection and persist in the reservoir. nork Kelsie Brooks, Bradley R Jones, Dario A Dilernia, Daniel J Wilkins, Daniel T Claiborne, Samantha McInally, Jill Gilmour, William Kilembe, Jeffrey B Joy, Susan A Allen, Zabrina L Brumme, Eric Hunter

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Prevalence and Correlates of Pre-Treatment HIV Drug Resistance among HIV-Infected Children in Ethiopia nork Birkneh Tilahun Tadesse, Olivia Tsai, Adugna Chala, Tolossa Eticha Chaka, Temesgen Eromo, Hope R. Lapointe, Bemuluyigza Baraki, Aniqa Shahid, Sintayehu Tadesse, Eyasu Makonnen, Zabrina L. Brumme, Eleni Aklillu, Chanson J. Brumme

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Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag. nork Jonathan M Carlson, Zabrina L Brumme, Christine M Rousseau, Chanson J Brumme, Philippa Matthews, Carl Kadie, James I Mullins, Bruce D Walker, P Richard Harrigan, Philip J R Goulder, David Heckerman

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Molecular Epidemiology of HIV-1 in Ghana: Subtype Distribution, Drug Resistance and Coreceptor Usage nork Anna Appah, Charlotte J. Beelen, Don Kirkby, Winnie Dong, Aniqa Shahid, Brian Foley, Miriam Mensah, Vincent Ganu, Peter Puplampu, Linda E. Amoah, Nicholas I. Nii-Trebi, Chanson J. Brumme, Zabrina L. Brumme

Testu osoa