PD1 Expression in EGFRvIII-Directed CAR T Cell Infusion Product for Glioblastoma Is Associated with Clinical Response by Oliver Y. Tang, Oliver Y. Tang, Oliver Y. Tang, Oliver Y. Tang, Lifeng Tian, Todd Yoder, Rong Xu, Irina Kulikovskaya, Irina Kulikovskaya, Minnal Gupta, Minnal Gupta, Jan Joseph Melenhorst, Jan Joseph Melenhorst, Jan Joseph Melenhorst, Simon F. Lacey, Simon F. Lacey, Donald M. O’Rourke, Donald M. O’Rourke, Donald M. O’Rourke, Zev A. Binder, Zev A. Binder, Zev A. Binder

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Novel tri-specific T-cell engager targeting IL-13Rα2 and EGFRvIII provides long-term survival in heterogeneous GBM challenge and promotes antitumor cytotoxicity with patient immune... by David B Weiner, Donald O’Rourke, Kevin Liaw, Pratik S Bhojnagarwala, Devivasha Bordoloi, Daniel H Park, Nicholas J Tursi, Shushu Zhao, Zev A Binder

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High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms by Radhika Thokala, Radhika Thokala, Zev A. Binder, Zev A. Binder, Yibo Yin, Yibo Yin, Logan Zhang, Logan Zhang, Jiasi Vicky Zhang, Jiasi Vicky Zhang, Daniel Y. Zhang, Daniel Y. Zhang, Michael C. Milone, Michael C. Milone, Guo-li Ming, Hongjun Song, Hongjun Song, Donald M. O’Rourke, Donald M. O’Rourke

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The IAP antagonist birinapant enhances chimeric antigen receptor T cell therapy for glioblastoma by overcoming antigen heterogeneity by Edward Z. Song, Xin Wang, Benjamin I. Philipson, Qian Zhang, Radhika Thokala, Logan Zhang, Charles-Antoine Assenmacher, Zev A. Binder, Guo-li Ming, Donald M. O’Rourke, Hongjun Song, Michael C. Milone

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Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR-mutant glioblastoma by Igor Makhlin, Ryan D Salinas, Daniel Zhang, Fadi Jacob, Gou-li Ming, Hongjun Song, Deeksha Saxena, Jay F Dorsey, MacLean P Nasrallah, Jennifer JD Morrissette, Zev A Binder, Donald M O'Rourke, Arati S Desai, Steven Brem, Stephen J Bagley

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Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines. by Zev A Binder, Kelli M Wilson, Vafi Salmasi, Brent A Orr, Charles G Eberhart, I-Mei Siu, Michael Lim, Jon D Weingart, Alfredo Quinones-Hinojosa, Chetan Bettegowda, Amin B Kassam, Alessandro Olivi, Henry Brem, Gregory J Riggins, Gary L Gallia

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Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome. by Zev A Binder, I-Mei Siu, Charles G Eberhart, Colette Ap Rhys, Ren-Yuan Bai, Verena Staedtke, Hao Zhang, Nicolas R Smoll, Steven Piantadosi, Sara G Piccirillo, Francesco Dimeco, Jon D Weingart, Angelo Vescovi, Alessandro Olivi, Gregory J Riggins, Gary L Gallia

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Integrating imaging and genomic data for the discovery of distinct glioblastoma subtypes: a joint learning approach by Jun Guo, Anahita Fathi Kazerooni, Erik Toorens, Hamed Akbari, Fanyang Yu, Chiharu Sako, Elizabeth Mamourian, Russell T. Shinohara, Constantinos Koumenis, Stephen J. Bagley, Jennifer J. D. Morrissette, Zev A. Binder, Steven Brem, Suyash Mohan, Robert A. Lustig, Donald M. O’Rourke, Tapan Ganguly, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos

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The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers by Anahita Fathi Kazerooni, Hamed Akbari, Xiaoju Hu, Vikas Bommineni, Dimitris Grigoriadis, Erik Toorens, Chiharu Sako, Elizabeth Mamourian, Dominique Ballinger, Robyn Sussman, Ashish Singh, Ioannis I. Verginadis, Nadia Dahmane, Constantinos Koumenis, Zev A. Binder, Stephen J. Bagley, Suyash Mohan, Artemis Hatzigeorgiou, Donald M. O’Rourke, Tapan Ganguly, Subhajyoti De, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos

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Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma by Gary L. Gallia, Ming Zhang, Yi Ning, Michael C. Haffner, Denise Batista, Zev A. Binder, Justin A. Bishop, Christine L. Hann, Ralph H. Hruban, Masaru Ishii, Alison P. Klein, Douglas D. Reh, Lisa M. Rooper, Vafi Salmasi, Rafael J. Tamargo, Qing Wang, Tara Williamson, Tianna Zhao, Ying Zou, Alan K. Meeker, Nishant Agrawal, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Chetan Bettegowda

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Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma by MacLean P. Nasrallah MD, PhD, Zev A. Binder MD, PhD, Derek A. Oldridge MD, PhD, Jianhua Zhao PhD, FACMG, David B. Lieberman MS, CGC, Jacquelyn J. Roth PhD, Christopher D. Watt MD, PhD, Shrey Sukhadia MS, Eva Klinman PhD, Robert D. Daber PhD, Arati Desai MD, Steven Brem MD, Donald M. O’Rourke MD, Jennifer J. D. Morrissette PhD

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The University of Pennsylvania glioblastoma (UPenn-GBM) cohort: advanced MRI, clinical, genomics, & radiomics by Spyridon Bakas, Chiharu Sako, Hamed Akbari, Michel Bilello, Aristeidis Sotiras, Gaurav Shukla, Jeffrey D. Rudie, Natali Flores Santamaría, Anahita Fathi Kazerooni, Sarthak Pati, Saima Rathore, Elizabeth Mamourian, Sung Min Ha, William Parker, Jimit Doshi, Ujjwal Baid, Mark Bergman, Zev A. Binder, Ragini Verma, Robert A. Lustig, Arati S. Desai, Stephen J. Bagley, Zissimos Mourelatos, Jennifer Morrissette, Christopher D. Watt, Steven Brem, Ronald L. Wolf, Elias R. Melhem, MacLean P. Nasrallah, Suyash Mohan, Donald M. O’Rourke, Christos Davatzikos

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