Polynomial Mendelian randomization reveals non-linear causal effects for obesity-related traits by Jonathan Sulc, Jennifer Sjaarda, Zoltán Kutalik

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From pharmacogenetics to pharmaco-omics: Milestones and future directions by Chiara Auwerx, Marie C. Sadler, Alexandre Reymond, Zoltán Kutalik

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PheWAS-based clustering of Mendelian Randomisation instruments reveals distinct mechanism-specific causal effects between obesity and educational attainment by Liza Darrous, Gibran Hemani, George Davey Smith, Zoltán Kutalik

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Comparison of strategies to detect epistasis from eQTL data. by Karen Kapur, Thierry Schüpbach, Ioannis Xenarios, Zoltán Kutalik, Sven Bergmann

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Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility. by David Lamparter, Daniel Marbach, Rico Rueedi, Sven Bergmann, Zoltán Kutalik

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Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics. by David Lamparter, Daniel Marbach, Rico Rueedi, Zoltán Kutalik, Sven Bergmann

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Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases by Marie C. Sadler, Chiara Auwerx, Kaido Lepik, Eleonora Porcu, Zoltán Kutalik

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Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations by Chiara Auwerx, Marie C Sadler, Tristan Woh, Alexandre Reymond, Zoltán Kutalik, Eleonora Porcu

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Parent-of-Origin inference for biobanks by Robin J. Hofmeister, Simone Rubinacci, Diogo M. Ribeiro, Alfonso Buil, Zoltán Kutalik, Olivier Delaneau

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Improving polygenic prediction with genetically inferred ancestry by Olivier Naret, Zoltan Kutalik, Flavia Hodel, Zhi Ming Xu, Pedro Marques-Vidal, Jacques Fellay

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Cannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study by Roxane de La Harpe, Tabea Schoeler, Christian W. Thorball, Aurélien Thomas, Zoltán Kutalik, Julien Vaucher

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A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications by Thomas W Winkler, Felix Günther, Simon Höllerer, Martina Zimmermann, Ruth JF Loos, Zoltán Kutalik, Iris M Heid

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C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis. by Kaido Lepik, Tarmo Annilo, Viktorija Kukuškina, eQTLGen Consortium, Kai Kisand, Zoltán Kutalik, Pärt Peterson, Hedi Peterson

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Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits by Eleonora Porcu, Sina Rüeger, Kaido Lepik, eQTLGen Consortium, BIOS Consortium, Federico A. Santoni, Alexandre Reymond, Zoltán Kutalik

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Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains. by Corinne Berthonneche, Bastian Peter, Fanny Schüpfer, Pamela Hayoz, Zoltán Kutalik, Hugues Abriel, Thierry Pedrazzini, Jacques S Beckmann, Sven Bergmann, Fabienne Maurer

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Risk prediction of developing venous thrombosis in combined oral contraceptive users. by Aaron McDaid, Emmanuelle Logette, Valérie Buchillier, Maude Muriset, Pierre Suchon, Thierry Daniel Pache, Goranka Tanackovic, Zoltán Kutalik, Joëlle Michaud

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Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy. by Rico Rueedi, Roger Mallol, Johannes Raffler, David Lamparter, Nele Friedrich, Peter Vollenweider, Gérard Waeber, Gabi Kastenmüller, Zoltán Kutalik, Sven Bergmann

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Quantification of the overall contribution of gene-environment interaction for obesity-related traits by Jonathan Sulc, Ninon Mounier, Felix Günther, Thomas Winkler, Andrew R. Wood, Timothy M. Frayling, Iris M. Heid, Matthew R. Robinson, Zoltán Kutalik

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Genetic insights into the causal relationship between physical activity and cognitive functioning by Boris Cheval, Liza Darrous, Karmel W. Choi, Yann C. Klimentidis, David A. Raichlen, Gene E. Alexander, Stéphane Cullati, Zoltán Kutalik, Matthieu P. Boisgontier

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Rare copy-number variants as modulators of common disease susceptibility by Chiara Auwerx, Maarja Jõeloo, Marie C. Sadler, Nicolò Tesio, Sven Ojavee, Charlie J. Clark, Reedik Mägi, Estonian Biobank Research Team, Alexandre Reymond, Zoltán Kutalik

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