TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors by de Oliveira, ÉA, Chauhan, J, da Silva, JR, da Costa Carvalho, LA, Dias, D, de Carvalho, DG, Watanabe, LRM, Rebecca, VW, Mills, G, Lu, Y, da Silva, ASF, Consolaro, MEL, Herlyn, M, Possik, PA, Goding, C, Maria-Engler, SS