Pooled safety analysis of evolocumab in over 6000 patients from double-blind and open-label extension studies gan Toth, P, Descamps, O, Genest, J, Sattar, N, Preiss, D, Dent, R, Djedjos, C, Wu, Y, Geller, M, Uhart, M, Somaratne, R, Wasserman, S, for the PROFICIO Investigators