Management and Quality Control of Large Neuroimaging Datasets: Developments From the Barcelonaβeta Brain Research Center by Jordi Huguet, Carles Falcon, David Fusté, Sergi Girona, David Vicente, José Luis Molinuevo, Juan Domingo Gispert, Grégory Operto, for the ALFA Study

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White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes by Grégory Operto, Raffaele Cacciaglia, Oriol Grau-Rivera, Carles Falcon, Anna Brugulat-Serrat, Pablo Ródenas, Rubén Ramos, Sebastián Morán, Manel Esteller, Nuria Bargalló, José Luis Molinuevo, Juan Domingo Gispert, for the ALFA Study

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Spatial patterns of white matter hyperintensities associated with Alzheimer’s disease risk factors in a cognitively healthy middle-aged cohort by Gemma Salvadó, Anna Brugulat-Serrat, Carole H. Sudre, Oriol Grau-Rivera, Marc Suárez-Calvet, Carles Falcon, Karine Fauria, M. Jorge Cardoso, Frederik Barkhof, José Luis Molinuevo, Juan Domingo Gispert, for the ALFA Study

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Omega‐3 blood biomarkers relate to brain glucose uptake in individuals at risk of Alzheimer's disease dementia by Iolanda Lázaro, Oriol Grau‐Rivera, Marc Suárez‐Calvet, Karine Fauria, Carolina Minguillón, Mahnaz Shekari, Carles Falcón, Marina García‐Prat, Jordi Huguet, José Luis Molinuevo, Juan‐Domingo Gispert, Aleix Sala‐Vila, for the ALFA study

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Brain correlates of urban environmental exposures in cognitively unimpaired individuals at increased risk for Alzheimer's disease: A study on Barcelona's population by Carles Falcón, Mireia Gascon, José Luis Molinuevo, Grégory Operto, Marta Cirach, Xavier Gotsens, Karine Fauria, Eider M. Arenaza‐Urquijo, Jesús Pujol, Jordi Sunyer, Mark J. Nieuwenhuijsen, Juan Domingo Gispert, Marta Crous‐Bou, for the ALFA Study

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Association between insomnia and cognitive performance, gray matter volume, and white matter microstructure in cognitively unimpaired adults by Oriol Grau-Rivera, Grégory Operto, Carles Falcón, Gonzalo Sánchez-Benavides, Raffaele Cacciaglia, Anna Brugulat-Serrat, Nina Gramunt, Gemma Salvadó, Marc Suárez-Calvet, Carolina Minguillon, Álex Iranzo, Juan Domingo Gispert, José Luis Molinuevo, for the ALFA Study

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The Clinical Development of Taldefgrobep Alfa: An Anti-Myostatin Adnectin for the Treatment of Duchenne Muscular Dystrophy by Francesco Muntoni, Barry J. Byrne, Hugh J. McMillan, Monique M. Ryan, Brenda L. Wong, Juergen Dukart, Amita Bansal, Valerie Cosson, Roxana Dreghici, Maitea Guridi, Michael Rabbia, Hannah Staunton, Giridhar S. Tirucherai, Karl Yen, Xiling Yuan, Kathryn R. Wagner, the Taldefgrobep Alfa Study Group

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Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers by Gemma Salvadó, José Luis Molinuevo, Anna Brugulat-Serrat, Carles Falcon, Oriol Grau-Rivera, Marc Suárez-Calvet, Javier Pavia, Aida Niñerola-Baizán, Andrés Perissinotti, Francisco Lomeña, Carolina Minguillon, Karine Fauria, Henrik Zetterberg, Kaj Blennow, Juan Domingo Gispert, for the Alzheimer’s Disease Neuroimaging Initiative, for the ALFA Study

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Subjective cognitive decline and anxious/depressive symptoms during the COVID-19 pandemic: what is the role of stress perception, stress resilience, and β-amyloid? by Muge Akinci, Gonzalo Sánchez-Benavides, Anna Brugulat-Serrat, Cleofé Peña-Gómez, Eleni Palpatzis, Mahnaz Shekari, Carme Deulofeu, Sherezade Fuentes-Julian, Gemma Salvadó, José Maria González-de-Echávarri, Marc Suárez-Calvet, Carolina Minguillón, Karine Fauria, José Luis Molinuevo, Juan Domingo Gispert, Oriol Grau-Rivera, Eider M. Arenaza-Urquijo, for the ALFA Study

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Impact of gender on the willingness to participate in clinical trials and undergo related procedures in individuals from an Alzheimer’s prevention research cohort by Lidia Canals-Gispert, Alba Cañas-Martínez, Gema Huesa, Marc Suárez-Calvet Alomà, Marta Milà-Alomà, Eider Arenaza-Urquijo, Davide Cirillo, Annemarie Schumacher Dimech, Maria Florencia Iulita, Julie Novakova Martinkova, Maria Carmela Tartaglia, Frances-Catherine Quevenco, Antonella Santuccione Chadha, Gonzalo Sánchez-Benavides, Carolina Minguillón, Maria Teresa Ferretti, Karine Fauria, Anna Brugulat-Serrat, for the ALFA Study

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Data-driven CSF biomarker profiling: imaging and clinical outcomes in a cohort at risk of Alzheimer’s disease by Georgette Argiris, Muge Akinci, Cleofé Peña-Gómez, Eleni Palpatzis, Marina Garcia-Prat, Mahnaz Shekari, Kaj Blennow, Henrik Zetterberg, Gwendlyn Kollmorgen, Clara Quijano-Rubio, Nicholas J. Ashton, Thomas K. Karikari, Ann Brinkmalm-Westman, Juan Lantero-Rodriguez, Karine Fauria, Gonzalo Sánchez-Benavides, Oriol Grau-Rivera, Marc Suárez-Calvet, Eider M. Arenaza-Urquijo, for the ALFA study

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Association of weight change with cerebrospinal fluid biomarkers and amyloid positron emission tomography in preclinical Alzheimer’s disease by Oriol Grau-Rivera, Irene Navalpotro-Gomez, Gonzalo Sánchez-Benavides, Marc Suárez-Calvet, Marta Milà-Alomà, Eider M. Arenaza-Urquijo, Gemma Salvadó, Aleix Sala-Vila, Mahnaz Shekari, José Maria González-de-Echávarri, Carolina Minguillón, Aida Niñerola-Baizán, Andrés Perissinotti, Maryline Simon, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow, Juan Domingo Gispert, José Luis Molinuevo, for the ALFA Study

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Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study by Blanca Rodríguez-Fernández, Natalia Vilor-Tejedor, Eider M. Arenaza-Urquijo, Gonzalo Sánchez-Benavides, Marc Suárez-Calvet, Grégory Operto, Carolina Minguillón, Karine Fauria, Gwendlyn Kollmorgen, Ivonne Suridjan, Manuel Castro de Moura, David Piñeyro, Manel Esteller, Kaj Blennow, Henrik Zetterberg, Immaculata De Vivo, José Luis Molinuevo, Arcadi Navarro, Juan Domingo Gispert, Aleix Sala-Vila, Marta Crous-Bou, for the ALFA study

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APOE -ε4 modulates the association between regional amyloid deposition and cognitive performance in cognitively unimpaired middle-aged individuals by Anna Brugulat-Serrat, Gonzalo Sánchez-Benavides, Raffaele Cacciaglia, Gemma Salvadó, Mahnaz Shekari, Lyduine E. Collij, Christopher Buckley, Bart N. M. van Berckel, Andrés Perissinotti, Aida Niñerola-Baizán, Marta Milà-Alomà, Natàlia Vilor-Tejedor, Grégory Operto, Carles Falcon, Oriol Grau-Rivera, Eider M. Arenaza-Urquijo, Carolina Minguillón, Karine Fauria, José Luis Molinuevo, Marc Suárez-Calvet, Juan Domingo Gispert, the ALFA Study

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Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer’s disease and neurodegeneration stra... by Irene Cumplido-Mayoral, Marina García-Prat, Grégory Operto, Carles Falcon, Mahnaz Shekari, Raffaele Cacciaglia, Marta Milà-Alomà, Luigi Lorenzini, Silvia Ingala, Alle Meije Wink, Henk JMM Mutsaerts, Carolina Minguillón, Karine Fauria, José Luis Molinuevo, Sven Haller, Gael Chetelat, Adam Waldman, Adam J Schwarz, Frederik Barkhof, Ivonne Suridjan, Gwendlyn Kollmorgen, Anna Bayfield, Henrik Zetterberg, Kaj Blennow, Marc Suárez-Calvet, Verónica Vilaplana, Juan Domingo Gispert, ALFA study, EPAD study, ADNI study, OASIS study

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Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected... by Marc Suárez‐Calvet, Thomas K Karikari, Nicholas J Ashton, Juan Lantero Rodríguez, Marta Milà‐Alomà, Juan Domingo Gispert, Gemma Salvadó, Carolina Minguillon, Karine Fauria, Mahnaz Shekari, Oriol Grau‐Rivera, Eider M Arenaza‐Urquijo, Aleix Sala‐Vila, Gonzalo Sánchez‐Benavides, José Maria González‐de‐Echávarri, Gwendlyn Kollmorgen, Erik Stoops, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, José Luis Molinuevo, for the ALFA Study, Annabella Beteta, Raffaele Cacciaglia, Alba Cañas, Carme Deulofeu, Irene Cumplido, Ruth Dominguez, Maria Emilio, Carles Falcon, Sherezade Fuentes, Laura Hernandez, Gema Huesa, Jordi Huguet, Paula Marne, Tania Menchón, Grégory Operto, Albina Polo, Sandra Pradas, Anna Soteras, Marc Vilanova, Natalia Vilor‐Tejedor

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