Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling nork Alexander Janssen, Mark Hoogendoorn, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT Study Group and SYMPHONY Consortium

Testu osoa

Deep compartment models: A deep learning approach for the reliable prediction of time‐series data in pharmacokinetic modeling nork Alexander Janssen, Frank W. G. Leebeek, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium

Testu osoa

PBPK modeling of recombinant factor IX Fc fusion protein (rFIXFc) and rFIX to characterize the binding to type 4 collagen in the extravascular space nork Michael E. Cloesmeijer, Erik Sjögren, Sjoerd F. Koopman, Peter. J. Lenting, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium

Testu osoa