Selective Inhibition of the Non-lysosomal Glucosylceramidase Gba2 and Elevation of Glucosylceramide in vivo: Consequences for Male Germ Cell Development by van der Spoel, A, Platt, F

The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction. by Platt, F, Boland, B, van der Spoel, A

Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation. by van der Spoel, A, Mott, R, Platt, F

Pharmacological impairment of acrosome formation and sperm head morphogenesis reveals essential role of glycosphingolipids in spermiogenesis by van der Spoel, A, Jeyakumar, M, Butters, T, Dwek, R, Platt, F

Long-term non-hormonal male contraception in mice using N-butyldeoxynojirimycin. by Walden, C, Butters, T, Dwek, R, Platt, F, van der Spoel, A

N-butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice. by Priestman, D, van der Spoel, A, Butters, T, Dwek, R, Platt, F

The postacrosomal assembly of sperm head protein, PAWP, is independent of acrosome formation and dependent on microtubular manchette transport. by Wu, A, Sutovsky, P, Xu, W, van der Spoel, A, Platt, F, Oko, R

Alkylated imino sugars, reversible male infertility-inducing agents, do not affect the genetic integrity of male mouse germ cells during short-term treatment despite induction of s... by Suganuma, R, Walden, C, Butters, T, Platt, F, Dwek, R, Yanagimachi, R, van der Spoel, A

Alkylated imino sugars, reversible male infertility-inducing agents, do not change the genetic integrity of male mouse germ cells, despite severe deformities of spermatozoal struct... by Suganuma, R, Walden, C, Platt, F, Butters, T, Dwek, R, Yanagimachi, R, van der Spoel, A

Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception. by van der Spoel, A, Jeyakumar, M, Butters, T, Charlton, H, Moore, H, Dwek, R, Platt, F

Accumulation of glucosylceramide in murine testis, caused by inhibition of beta-glucosidase 2: implications for spermatogenesis. by Walden, C, Sandhoff, R, Chuang, C, Yildiz, Y, Butters, T, Dwek, R, Platt, F, van der Spoel, A

The Role of the GlcCer Transfer Protein FAPP2 at the Golgi Complex by D'Angelo, G, Polishchuk, E, Polishchuk, R, Mattjus, P, Van der Spoel, A, Platt, F, De Matteis, A

Glycomimetic affinity-enrichment proteomics identifies partners for a clinically-utilized iminosugar by Cruz, I, Barry, C, Kramer, H, Chuang, C, Lloyd, S, van der Spoel, A, Platt, F, Yang, M, Davis, B

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study. by Bone, W, Walden, C, Fritsch, M, Voigtmann, U, Leifke, E, Gottwald, U, Boomkamp, S, Platt, F, van der Spoel, A

Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis. by Jeyakumar, M, Thomas, R, Elliot-Smith, E, Smith, D, van der Spoel, A, d'Azzo, A, Perry, V, Butters, T, Dwek, R, Platt, F

Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis. by Elliot-Smith, E, Speak, A, Lloyd-Evans, E, Smith, D, van der Spoel, A, Jeyakumar, M, Butters, T, Dwek, R, d'Azzo, A, Platt, F

Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3. by Rabionet, M, van der Spoel, A, Chuang, C, von Tümpling-Radosta, B, Litjens, M, Bouwmeester, D, Hellbusch, C, Körner, C, Wiegandt, H, Gorgas, K, Platt, F, Gröne, H, Sandhoff, R

Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. by D'Angelo, G, Polishchuk, E, Di Tullio, G, Santoro, M, Di Campli, A, Godi, A, West, G, Bielawski, J, Chuang, C, van der Spoel, A, Platt, F, Hannun, Y, Polishchuk, R, Mattjus, P, Matteis, D