Drug Discrimination : Applications to Medicinal Chemistry and Drug Studies /
Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents. Drug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as the subjective st...
| Main Authors: | , |
|---|---|
| Format: | text |
| Language: | eng |
| Published: |
Hoboken, NJ. : Wiley,
2011
|
| Subjects: |
| _version_ | 1826449617761337344 |
|---|---|
| author | Glennon, Richard A., 1945-, editor 521248 Young, Richard, 1952-, editor 521249 |
| author_facet | Glennon, Richard A., 1945-, editor 521248 Young, Richard, 1952-, editor 521249 |
| author_sort | Glennon, Richard A., 1945-, editor 521248 |
| collection | OCEAN |
| description | Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents. Drug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as the subjective stimulus. Although the procedure does require some effort to implement, it can be an extremely important tool for understanding drug action. Whereas medicinal chemists should come to learn the types of information that drug discrimination studies can offer, pharmacologists and psychologists might come to realize how medicinal chemists can apply the types of information that the paradigm routinely provides. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies provides in-depth analyses of the nature and use of drugs as discriminative stimuli and bridges some of the numerous gaps between medicinal chemistry, pharmacology, and psychology. Stressing the practical aspects of drug discrimination, including types of procedures, study design, data, and interpretation, the book details the advantages and limitations of drug discrimination studies versus other pharmacologic evaluations. Practical information from leading researchers in the field addresses specific topics and techniques that are of interest in drug discovery, evaluation, and development. A groundbreaking new guide to the applications of drug discrimination studies for medicinal chemistry and neuroscience, Drug Discrimination is essential for any scientist, researcher, or student whose interests involve the design, development, and/or action of drugs acting at the level of the central nervous system. |
| first_indexed | 2024-03-05T11:43:06Z |
| format | text |
| id | KOHA-OAI-TEST:464413 |
| institution | Universiti Teknologi Malaysia - OCEAN |
| language | eng |
| last_indexed | 2024-03-05T11:43:06Z |
| publishDate | 2011 |
| publisher | Hoboken, NJ. : Wiley, |
| record_format | dspace |
| spelling | KOHA-OAI-TEST:4644132021-06-16T06:35:35ZDrug Discrimination : Applications to Medicinal Chemistry and Drug Studies / Glennon, Richard A., 1945-, editor 521248 Young, Richard, 1952-, editor 521249 textHoboken, NJ. : Wiley,2011©2011engDrug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents. Drug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as the subjective stimulus. Although the procedure does require some effort to implement, it can be an extremely important tool for understanding drug action. Whereas medicinal chemists should come to learn the types of information that drug discrimination studies can offer, pharmacologists and psychologists might come to realize how medicinal chemists can apply the types of information that the paradigm routinely provides. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies provides in-depth analyses of the nature and use of drugs as discriminative stimuli and bridges some of the numerous gaps between medicinal chemistry, pharmacology, and psychology. Stressing the practical aspects of drug discrimination, including types of procedures, study design, data, and interpretation, the book details the advantages and limitations of drug discrimination studies versus other pharmacologic evaluations. Practical information from leading researchers in the field addresses specific topics and techniques that are of interest in drug discovery, evaluation, and development. A groundbreaking new guide to the applications of drug discrimination studies for medicinal chemistry and neuroscience, Drug Discrimination is essential for any scientist, researcher, or student whose interests involve the design, development, and/or action of drugs acting at the level of the central nervous system.Includes bibliographical references and index.An introduction to drug discrimination -- Methodological considerations -- Drug discrimination : practical considerations -- Role of stereochemistry in drug discrimination studies -- Drug discrimination and in vivo structure-activity relationships -- Drug discrimination and mechanisms of drug action -- Drug discrimination and development of novel agents and pharmacological tools -- Perceptual drug discriminative aspects of the endocannabinoid signaling system in animals and man -- Discriminative stimulus properties of receptor antagonists -- The discrimination of drug mixtures -- Making the right choice : lessons from drug discrimination for research on drug reinforcement and drug self-administration -- Inhalant drug discrimination: methodology, literature review, and future directions -- Drug discrimination studies in rhesus monkeys : drug dependence and withdrawal -- Human drug discrimination : methodological considerations and application to elucidating the neuropharmacology of amphetamines -- Nicotine discrimination in humans -- Drug discrimination : a perspective.Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agents. Drug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as the subjective stimulus. Although the procedure does require some effort to implement, it can be an extremely important tool for understanding drug action. Whereas medicinal chemists should come to learn the types of information that drug discrimination studies can offer, pharmacologists and psychologists might come to realize how medicinal chemists can apply the types of information that the paradigm routinely provides. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies provides in-depth analyses of the nature and use of drugs as discriminative stimuli and bridges some of the numerous gaps between medicinal chemistry, pharmacology, and psychology. Stressing the practical aspects of drug discrimination, including types of procedures, study design, data, and interpretation, the book details the advantages and limitations of drug discrimination studies versus other pharmacologic evaluations. Practical information from leading researchers in the field addresses specific topics and techniques that are of interest in drug discovery, evaluation, and development. A groundbreaking new guide to the applications of drug discrimination studies for medicinal chemistry and neuroscience, Drug Discrimination is essential for any scientist, researcher, or student whose interests involve the design, development, and/or action of drugs acting at the level of the central nervous system.PSZ_JBDrug discrimination (Pharmacology)URN:ISBN:9780470433522 |
| spellingShingle | Drug discrimination (Pharmacology) Glennon, Richard A., 1945-, editor 521248 Young, Richard, 1952-, editor 521249 Drug Discrimination : Applications to Medicinal Chemistry and Drug Studies / |
| title | Drug Discrimination : Applications to Medicinal Chemistry and Drug Studies / |
| title_full | Drug Discrimination : Applications to Medicinal Chemistry and Drug Studies / |
| title_fullStr | Drug Discrimination : Applications to Medicinal Chemistry and Drug Studies / |
| title_full_unstemmed | Drug Discrimination : Applications to Medicinal Chemistry and Drug Studies / |
| title_short | Drug Discrimination : Applications to Medicinal Chemistry and Drug Studies / |
| title_sort | drug discrimination applications to medicinal chemistry and drug studies |
| topic | Drug discrimination (Pharmacology) |
| work_keys_str_mv | AT glennonricharda1945editor521248 drugdiscriminationapplicationstomedicinalchemistryanddrugstudies AT youngrichard1952editor521249 drugdiscriminationapplicationstomedicinalchemistryanddrugstudies |