Mass Spectrometry in Metabolomics : Methods and Protocols /
Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples...
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New York : Humana Press,
2014
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| _version_ | 1796757366172024832 |
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| author | Raftery, Daniel, editor |
| author_facet | Raftery, Daniel, editor |
| author_sort | Raftery, Daniel, editor |
| collection | OCEAN |
| description | Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics. |
| first_indexed | 2024-03-05T15:29:12Z |
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| id | KOHA-OAI-TEST:539402 |
| institution | Universiti Teknologi Malaysia - OCEAN |
| language | eng |
| last_indexed | 2024-03-05T15:29:12Z |
| publishDate | 2014 |
| publisher | New York : Humana Press, |
| record_format | dspace |
| spelling | KOHA-OAI-TEST:5394022020-12-19T17:20:21ZMass Spectrometry in Metabolomics : Methods and Protocols / Raftery, Daniel, editor New York : Humana Press,2014engMetabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics.Includes bibliographical references and indexPart I. Historical and Methodology Overview -- 1. Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges G. A. Nagana Gowda and Danijel Djukovic ; Part II. Global LC-MS Based Metabolic Profiling -- 2. Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Yunpeng Qi, Yunlong Song, Haiwei Gu, Guorong Fan, and Yifeng Chai -- 3. LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping PopulationsCamilla B. Hill, Antony Bacic, and Ute Roessner -- 4. Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry Young-Mi Go, Karan Uppal, Douglas I. Walker, ViLinh Tran, Lauriane Dury, Frederick H. Strobel, Helene Baubichon-Cortay, Kurt D. Pennell, James R. Roede, and Dean P. Jones -- 5. Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling Antoni Beltran, Sara Samino, and Oscar Yanes ; Part III. Global GC-MS and CE-MS Based Metabolic Profiling -- 6. Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection Luke C. Marney, Dr. Jamin C. Hoggard, Kristen J. Skogerboe, and Robert E. Synovec -- 7. Analysis of Mouse Liver Metabolites by GCxGC-TOF MS Xue Shi, Xinmin Yin, and Xiang Zhang -- 8. Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry Antonia Garcia, Shama Naz, and Coral Barbas ; Part IV. Isotope Labeling Methods -- 9. Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass SpectrometryRuokun Zhou and Liang Li -- 10. Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS AnalysisHans Fredrik Nyvold Kvitvang, Kare A. Kristiansen, Stina K. Lien, and Per Bruheim -- 11. Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MSRichard M. Higashi, Teresa W-M. Fan, Pawel K. Lorkiewicz, Hunter N.B. Moseley, and Andrew N. Lane ; Part V. Targeted Aqueous Metabolite Profiling -- 12. Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRMRu Wei, Guodong Li, and Albert B. Seymour Part VI. Lipid Profiling Methods -- 13. Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics Miao Wang and Xianlin Han -- 14. Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass SpectrometryMojgan Masoodi and Dietrich A. Volmer -- 15. Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species Juan Carlos Garcia-Canaveras, Maria Teresa Donato, and Agustin Lahoz ; Part VII. Profiling Volatile Organic Compounds -- 16. Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis Jan W. Dallinga, Agnieszka Smolinska, and Frederik-Jan van Schooten -- 17. Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs) Shucha Zhang and Daniel Raftery ; Part VIII. Profiling and Imaging using Atmospheric Sampling Methods -- 18. Metabolite Profiling by Direct Analysis in Real Time Mass Spectrometry Christina M. Jones, Maria Eugenia Monge, and Facundo M. Fernandez -- 19. Analysis of Dried Blood Spots using DESI Mass Spectrometry Justin M. Wiseman and Joseph H. Kennedy -- 20. DESI-MS Imaging of Lipids and Metabolites from Biological Samples Livia S. Eberlin -- 21. Metabolic Imaging using Nanostructure-Initiator Mass Spectrometry (NIMS) Katherine B. Louie and Trent R. Northen ; Part IX. Statistical Analysis Methods 22. Statistical Analysis and Modeling of Mass Spectrometry-Based Metabolomics Data Bowei Xi, Haiwei Gu, Hamid Baniasadi, and Daniel Raftery.Metabolomics is a fast growing field in systems biology and offers a powerful and promising approach for a large range of applications. Metabolomics focuses on deriving the concentrations and fluxes of low molecular weight metabolites in bio-fluids, cells or tissue, plants, foods and related samples and this information provides enormous detail on biological systems and their current status. Mass Spectrometry in Metabolomics: Methods and Protocols presents a broad coverage of the major mass spectrometry (MS)-based metabolomics methods and applications. MS is one of most powerful and commonly used analytical methods in metabolomics; because so many different MS systems are used in metabolomics, this volume includes a wide variety such as triple quads, time of flight, Fourier transform ion cyclotron resonance and even simple quadrupole systems. A wide range of studies are described, with samples ranging from blood and urine to tissue and even plants. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Mass Spectrometry in Metabolomics: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further the dynamic field of metabolomics.PAGOHL Metabolites Mass spectrometry MetabolomicsMass SpectrometryURN:ISBN:9781493912575 |
| spellingShingle | Metabolites Mass spectrometry Metabolomics Mass Spectrometry Raftery, Daniel, editor Mass Spectrometry in Metabolomics : Methods and Protocols / |
| title | Mass Spectrometry in Metabolomics : Methods and Protocols / |
| title_full | Mass Spectrometry in Metabolomics : Methods and Protocols / |
| title_fullStr | Mass Spectrometry in Metabolomics : Methods and Protocols / |
| title_full_unstemmed | Mass Spectrometry in Metabolomics : Methods and Protocols / |
| title_short | Mass Spectrometry in Metabolomics : Methods and Protocols / |
| title_sort | mass spectrometry in metabolomics methods and protocols |
| topic | Metabolites Mass spectrometry Metabolomics Mass Spectrometry |
| work_keys_str_mv | AT rafterydanieleditor massspectrometryinmetabolomicsmethodsandprotocols |