GENE DELIVERY : METHODS AND APPLICATIONS /
Gene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells. In addition, an update on ongoing and completed clinical studies with engineered mesenchymal stromal cells will be provided, as well...
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| Language: | eng |
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New York, NY : Nova Science Publishers,
2019
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| _version_ | 1826469062941605888 |
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| author | Zimmer, Vanessa, editor |
| author_facet | Zimmer, Vanessa, editor |
| author_sort | Zimmer, Vanessa, editor |
| collection | OCEAN |
| description | Gene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells. In addition, an update on ongoing and completed clinical studies with engineered mesenchymal stromal cells will be provided, as well as a snapshot of the advances and technical challenges yet to be addressed. Next, a variety of gene delivery systems including physical transfection techniques, virus-based delivery vectors, chemically engineered delivery systems and bio-inspired vehicles are reviewed and their strengths, shortcomings and biomedical applications are discussed. Selfish DNA called transposons capable of cutting out and pasting into the host genome are active throughout the phylogenetic kingdoms |
| first_indexed | 2024-03-05T16:27:42Z |
| format | |
| id | KOHA-OAI-TEST:558762 |
| institution | Universiti Teknologi Malaysia - OCEAN |
| language | eng |
| last_indexed | 2024-03-05T16:27:42Z |
| publishDate | 2019 |
| publisher | New York, NY : Nova Science Publishers, |
| record_format | dspace |
| spelling | KOHA-OAI-TEST:5587622020-12-19T17:21:08ZGENE DELIVERY : METHODS AND APPLICATIONS / Zimmer, Vanessa, editor New York, NY : Nova Science Publishers,2019engGene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells. In addition, an update on ongoing and completed clinical studies with engineered mesenchymal stromal cells will be provided, as well as a snapshot of the advances and technical challenges yet to be addressed. Next, a variety of gene delivery systems including physical transfection techniques, virus-based delivery vectors, chemically engineered delivery systems and bio-inspired vehicles are reviewed and their strengths, shortcomings and biomedical applications are discussed. Selfish DNA called transposons capable of cutting out and pasting into the host genome are active throughout the phylogenetic kingdomsIncludes bibliographical references and indexGene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells. In addition, an update on ongoing and completed clinical studies with engineered mesenchymal stromal cells will be provided, as well as a snapshot of the advances and technical challenges yet to be addressed. Next, a variety of gene delivery systems including physical transfection techniques, virus-based delivery vectors, chemically engineered delivery systems and bio-inspired vehicles are reviewed and their strengths, shortcomings and biomedical applications are discussed. Selfish DNA called transposons capable of cutting out and pasting into the host genome are active throughout the phylogenetic kingdomsPSZJBLGene therapyMesenchymal stem cellsURN:ISBN:9781536162684 |
| spellingShingle | Gene therapy Mesenchymal stem cells Zimmer, Vanessa, editor GENE DELIVERY : METHODS AND APPLICATIONS / |
| title | GENE DELIVERY : METHODS AND APPLICATIONS / |
| title_full | GENE DELIVERY : METHODS AND APPLICATIONS / |
| title_fullStr | GENE DELIVERY : METHODS AND APPLICATIONS / |
| title_full_unstemmed | GENE DELIVERY : METHODS AND APPLICATIONS / |
| title_short | GENE DELIVERY : METHODS AND APPLICATIONS / |
| title_sort | gene delivery methods and applications |
| topic | Gene therapy Mesenchymal stem cells |
| work_keys_str_mv | AT zimmervanessaeditor genedeliverymethodsandapplications |