IN VITRO AND IN VIVO TECHNIQUES with consideration of biological system /
This book consists of 10 chapters that address current issues involving in vitro and in vivo biological assays. In vitro and in vivo bioassays are essential for the discovery and development of biologically-active agents. The techniques ensure that the discovered agent is worthy of a clinical study....
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| Format: | text |
| Language: | eng |
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Johor Bahru,Johor : PENERBIT UTM PRESS,
2020
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| _version_ | 1803622368384385024 |
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| author | Saleha Shahar, editor 609260 Siti Pauliena Mohd. Bohari, editor 562347 Darshini Murugiah, contributor 632805 Haryati Jamaluddin, contributor 601462 Heeravathy Ramachandra, contributor 632790 Mohd. Helmi Sani, contributor 614697 Joazaizulfazli Jamalis, contributor 280753 Khairunadwa Jemon, contributor 601214 Law, Jia Xian, contributor 632804 Mei, Ling Ng, contributor 632792 Mohd. Faez Sharif, contributor 632798 Mohd. Hamzah Mohd. Nasir, contributor 632793 Muhammad Suhail Mohd. Ariffin, contributor 647722 Nadiah Sulaiman, contributor 543317 Loius, Naveen Eugene, contributor 632806 Nor Azlina Ahmad, contributor 288485 Nurul Aqilah Roslan, contributor 632801 Razauden Mohamed Zulkifli, contributor 601463 Saleha Shahar, contributor 609260 Siti Pauliena Mohd. Bohari, contributor 562347 Stella Joan Berendam, contributor 632788 Syazwani Itri Amran, contributor 609117 Zaidah Rahmat, contributor 614726 Zetty Amirah Zuilkifli, contributor 632791 |
| author_facet | Saleha Shahar, editor 609260 Siti Pauliena Mohd. Bohari, editor 562347 Darshini Murugiah, contributor 632805 Haryati Jamaluddin, contributor 601462 Heeravathy Ramachandra, contributor 632790 Mohd. Helmi Sani, contributor 614697 Joazaizulfazli Jamalis, contributor 280753 Khairunadwa Jemon, contributor 601214 Law, Jia Xian, contributor 632804 Mei, Ling Ng, contributor 632792 Mohd. Faez Sharif, contributor 632798 Mohd. Hamzah Mohd. Nasir, contributor 632793 Muhammad Suhail Mohd. Ariffin, contributor 647722 Nadiah Sulaiman, contributor 543317 Loius, Naveen Eugene, contributor 632806 Nor Azlina Ahmad, contributor 288485 Nurul Aqilah Roslan, contributor 632801 Razauden Mohamed Zulkifli, contributor 601463 Saleha Shahar, contributor 609260 Siti Pauliena Mohd. Bohari, contributor 562347 Stella Joan Berendam, contributor 632788 Syazwani Itri Amran, contributor 609117 Zaidah Rahmat, contributor 614726 Zetty Amirah Zuilkifli, contributor 632791 |
| author_sort | Saleha Shahar, editor 609260 |
| collection | OCEAN |
| description | This book consists of 10 chapters that address current issues involving in vitro and in vivo biological assays. In vitro and in vivo bioassays are essential for the discovery and development of biologically-active agents. The techniques ensure that the discovered agent is worthy of a clinical study. Unfortunately, many gave little thought on bioassays’ choice at the discovery stage, thus creating false leads, low-quality, and non-reproducible data. Many discoveries from such poorly-considered bioassays fall short at the clinical stage and waste precious resources. This book deliberates on the issues in popular in vitro and in vivo bioassays for a better perspective of their limitations, hence ensuring accurate interpretation of findings. The book carries two themes: in vitro and in vivo bioactivity assays. Chapters 1 to 6 discuss prevalent in vitro bioassays—antiviral, cytotoxicity, scratch assay, and cellular biochemistry assays. Chapters 7 to 9 introduce in vivo studies in small animals and 3D culture in a dish. The book also presents special feature of in silico approach in Chapter 10, which offers a glimpse of computational power to support in vitro and in vivo biological findings. Studies discussed in this volume will benefit researchers in academia and the industry whose work might be focused on discovering the next bioactive agents. |
| first_indexed | 2024-03-05T16:38:43Z |
| format | text |
| id | KOHA-OAI-TEST:590984 |
| institution | Universiti Teknologi Malaysia - OCEAN |
| language | eng |
| last_indexed | 2024-07-04T04:45:29Z |
| publishDate | 2020 |
| publisher | Johor Bahru,Johor : PENERBIT UTM PRESS, |
| record_format | dspace |
| spelling | KOHA-OAI-TEST:5909842024-07-04T03:56:31ZIN VITRO AND IN VIVO TECHNIQUES with consideration of biological system / Saleha Shahar, editor 609260 Siti Pauliena Mohd. Bohari, editor 562347 Darshini Murugiah, contributor 632805 Haryati Jamaluddin, contributor 601462 Heeravathy Ramachandra, contributor 632790 Mohd. Helmi Sani, contributor 614697 Joazaizulfazli Jamalis, contributor 280753 Khairunadwa Jemon, contributor 601214 Law, Jia Xian, contributor 632804 Mei, Ling Ng, contributor 632792 Mohd. Faez Sharif, contributor 632798 Mohd. Hamzah Mohd. Nasir, contributor 632793 Muhammad Suhail Mohd. Ariffin, contributor 647722 Nadiah Sulaiman, contributor 543317 Loius, Naveen Eugene, contributor 632806 Nor Azlina Ahmad, contributor 288485 Nurul Aqilah Roslan, contributor 632801 Razauden Mohamed Zulkifli, contributor 601463 Saleha Shahar, contributor 609260 Siti Pauliena Mohd. Bohari, contributor 562347 Stella Joan Berendam, contributor 632788 Syazwani Itri Amran, contributor 609117 Zaidah Rahmat, contributor 614726 Zetty Amirah Zuilkifli, contributor 632791 text Book chapter 481883 Johor Bahru,Johor : PENERBIT UTM PRESS,2020©2020engThis book consists of 10 chapters that address current issues involving in vitro and in vivo biological assays. In vitro and in vivo bioassays are essential for the discovery and development of biologically-active agents. The techniques ensure that the discovered agent is worthy of a clinical study. Unfortunately, many gave little thought on bioassays’ choice at the discovery stage, thus creating false leads, low-quality, and non-reproducible data. Many discoveries from such poorly-considered bioassays fall short at the clinical stage and waste precious resources. This book deliberates on the issues in popular in vitro and in vivo bioassays for a better perspective of their limitations, hence ensuring accurate interpretation of findings. The book carries two themes: in vitro and in vivo bioactivity assays. Chapters 1 to 6 discuss prevalent in vitro bioassays—antiviral, cytotoxicity, scratch assay, and cellular biochemistry assays. Chapters 7 to 9 introduce in vivo studies in small animals and 3D culture in a dish. The book also presents special feature of in silico approach in Chapter 10, which offers a glimpse of computational power to support in vitro and in vivo biological findings. Studies discussed in this volume will benefit researchers in academia and the industry whose work might be focused on discovering the next bioactive agents.Includes bibliographical references and index.This book consists of 10 chapters that address current issues involving in vitro and in vivo biological assays. In vitro and in vivo bioassays are essential for the discovery and development of biologically-active agents. The techniques ensure that the discovered agent is worthy of a clinical study. Unfortunately, many gave little thought on bioassays’ choice at the discovery stage, thus creating false leads, low-quality, and non-reproducible data. Many discoveries from such poorly-considered bioassays fall short at the clinical stage and waste precious resources. This book deliberates on the issues in popular in vitro and in vivo bioassays for a better perspective of their limitations, hence ensuring accurate interpretation of findings. The book carries two themes: in vitro and in vivo bioactivity assays. Chapters 1 to 6 discuss prevalent in vitro bioassays—antiviral, cytotoxicity, scratch assay, and cellular biochemistry assays. Chapters 7 to 9 introduce in vivo studies in small animals and 3D culture in a dish. The book also presents special feature of in silico approach in Chapter 10, which offers a glimpse of computational power to support in vitro and in vivo biological findings. Studies discussed in this volume will benefit researchers in academia and the industry whose work might be focused on discovering the next bioactive agents.KK-PENERBIT_UTMBiological systemsBiological assayURN:ISBN:9789835217401 |
| spellingShingle | Biological systems Biological assay Saleha Shahar, editor 609260 Siti Pauliena Mohd. Bohari, editor 562347 Darshini Murugiah, contributor 632805 Haryati Jamaluddin, contributor 601462 Heeravathy Ramachandra, contributor 632790 Mohd. Helmi Sani, contributor 614697 Joazaizulfazli Jamalis, contributor 280753 Khairunadwa Jemon, contributor 601214 Law, Jia Xian, contributor 632804 Mei, Ling Ng, contributor 632792 Mohd. Faez Sharif, contributor 632798 Mohd. Hamzah Mohd. Nasir, contributor 632793 Muhammad Suhail Mohd. Ariffin, contributor 647722 Nadiah Sulaiman, contributor 543317 Loius, Naveen Eugene, contributor 632806 Nor Azlina Ahmad, contributor 288485 Nurul Aqilah Roslan, contributor 632801 Razauden Mohamed Zulkifli, contributor 601463 Saleha Shahar, contributor 609260 Siti Pauliena Mohd. Bohari, contributor 562347 Stella Joan Berendam, contributor 632788 Syazwani Itri Amran, contributor 609117 Zaidah Rahmat, contributor 614726 Zetty Amirah Zuilkifli, contributor 632791 IN VITRO AND IN VIVO TECHNIQUES with consideration of biological system / |
| title | IN VITRO AND IN VIVO TECHNIQUES with consideration of biological system / |
| title_full | IN VITRO AND IN VIVO TECHNIQUES with consideration of biological system / |
| title_fullStr | IN VITRO AND IN VIVO TECHNIQUES with consideration of biological system / |
| title_full_unstemmed | IN VITRO AND IN VIVO TECHNIQUES with consideration of biological system / |
| title_short | IN VITRO AND IN VIVO TECHNIQUES with consideration of biological system / |
| title_sort | in vitro and in vivo techniques with consideration of biological system |
| topic | Biological systems Biological assay |
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