| Summary: | Quantum dots (QDs) are hybrid organic/inorganic nanoparticles with novel physical properties. QDs have two components: an inorganic core and an optically active coated shell. Moreover, surface coatings can be applied to QDs to modify the particle as needed for experiments. Hydrophilic coatings prevent leaking of metal cargo from the core, enhancing the solubility in biological contexts and bind molecules, such as receptor–ligands, antibodies, therapeutic, and diagnostic macromolecules for enhanced effects. Their high surface-to-volume ratio allows multiple functional groups to attach onto the surface of the particles at constant surface volume. Silicon-, gallium-, indium-, or germanium-based; cadmium-based; and carbon-based QDs have already been used in many applications, such as imaging probes for the engineering of multifunctional nanodevices. Superior properties of QDs make them an excellent system in technology and biotechnology.
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