Single-stage DNA splicing system via Yusof-Goode approach

Yusof-Goode (Y-G) rule is the new translucent way representing the rule in splicing system under the framework of formal language theory. The motivation behind using the Y-G approach is to simulate the actual recombinant behaviours of deoxyribonucleic acid (DNA) molecules. The current laboratory exp...

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Main Author: Wen Li, Lim
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/10979/19/FIST%20-%20LIM%20WEN%20LI%20%28CD8908%29.pdf
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author Wen Li, Lim
author_facet Wen Li, Lim
author_sort Wen Li, Lim
collection UMP
description Yusof-Goode (Y-G) rule is the new translucent way representing the rule in splicing system under the framework of formal language theory. The motivation behind using the Y-G approach is to simulate the actual recombinant behaviours of deoxyribonucleic acid (DNA) molecules. The current laboratory experimental approaches to obtain the product of the DNA splicing process involve time and cost with high probability of not getting the desired results. Hence, in this research, a mathematical concept of single-stage splicing language restricted to at most two non-palindromic initial strings and two rules with one recognition site is introduced via Y-G model. In addition, the characteristics of rule are investigated by providing mathematical proofs. Based on the characteristics of rule, some theorems and lemmas have been formulated to predict the number types of single-stage splicing language of Y-G splicing system. Furthermore, in order to determine the characterizations of single-stage splicing language, a model is developed via limit adjacency matrix approach. The limit adjacency matrix can also be used to predict the number types of transient, inert persistent and active persistent limit language. Finally, a graphic user interface and a computational model of single-stage limit language are developed using Microsoft Visual Basic (VB) programming code focusing on prediction of the conceivable resulted molecules, the number types of single-stage splicing language as well as the behaviours of single-stage splicing language
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spelling UMPir109792021-11-02T02:32:36Z http://umpir.ump.edu.my/id/eprint/10979/ Single-stage DNA splicing system via Yusof-Goode approach Wen Li, Lim QA Mathematics Yusof-Goode (Y-G) rule is the new translucent way representing the rule in splicing system under the framework of formal language theory. The motivation behind using the Y-G approach is to simulate the actual recombinant behaviours of deoxyribonucleic acid (DNA) molecules. The current laboratory experimental approaches to obtain the product of the DNA splicing process involve time and cost with high probability of not getting the desired results. Hence, in this research, a mathematical concept of single-stage splicing language restricted to at most two non-palindromic initial strings and two rules with one recognition site is introduced via Y-G model. In addition, the characteristics of rule are investigated by providing mathematical proofs. Based on the characteristics of rule, some theorems and lemmas have been formulated to predict the number types of single-stage splicing language of Y-G splicing system. Furthermore, in order to determine the characterizations of single-stage splicing language, a model is developed via limit adjacency matrix approach. The limit adjacency matrix can also be used to predict the number types of transient, inert persistent and active persistent limit language. Finally, a graphic user interface and a computational model of single-stage limit language are developed using Microsoft Visual Basic (VB) programming code focusing on prediction of the conceivable resulted molecules, the number types of single-stage splicing language as well as the behaviours of single-stage splicing language 2015-04 Thesis NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/10979/19/FIST%20-%20LIM%20WEN%20LI%20%28CD8908%29.pdf Wen Li, Lim (2015) Single-stage DNA splicing system via Yusof-Goode approach. Masters thesis, Universiti Malaysia Pahang (Contributors, UNSPECIFIED: UNSPECIFIED).
spellingShingle QA Mathematics
Wen Li, Lim
Single-stage DNA splicing system via Yusof-Goode approach
title Single-stage DNA splicing system via Yusof-Goode approach
title_full Single-stage DNA splicing system via Yusof-Goode approach
title_fullStr Single-stage DNA splicing system via Yusof-Goode approach
title_full_unstemmed Single-stage DNA splicing system via Yusof-Goode approach
title_short Single-stage DNA splicing system via Yusof-Goode approach
title_sort single stage dna splicing system via yusof goode approach
topic QA Mathematics
url http://umpir.ump.edu.my/id/eprint/10979/19/FIST%20-%20LIM%20WEN%20LI%20%28CD8908%29.pdf
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