Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network

Early treatment of sepsis can reduce mortality and improve a patient condition. However, the lack of clear information and accurate methods of diagnosing sepsis at an early stage makes it become a significant challenge. The decision to start, continue or stop antimicrobial therapy is normally base o...

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Main Authors: F. M., Suhaimi, J. G., Chase, G. M., Shaw, Ummu Kulthum, Jamaludin, Normy Norfiza, A. Razak
Other Authors: Fatimah, Ibrahim
Format: Book Chapter
Language:English
Published: Springer 2016
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/11575/1/Prediction%20of%20Sepsis%20Progression%20in%20Critical%20Illness%20Using%20Artificial%20Neural%20Network.pdf
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author F. M., Suhaimi
J. G., Chase
G. M., Shaw
Ummu Kulthum, Jamaludin
Normy Norfiza, A. Razak
author2 Fatimah, Ibrahim
author_facet Fatimah, Ibrahim
F. M., Suhaimi
J. G., Chase
G. M., Shaw
Ummu Kulthum, Jamaludin
Normy Norfiza, A. Razak
author_sort F. M., Suhaimi
collection UMP
description Early treatment of sepsis can reduce mortality and improve a patient condition. However, the lack of clear information and accurate methods of diagnosing sepsis at an early stage makes it become a significant challenge. The decision to start, continue or stop antimicrobial therapy is normally base on clinical judgment since blood cultures will be negative in the majority of cases of septic shock or sepsis. However, clinical guidelines are still required to provide guidance for the clinician caring for a patient with severe sepsis or septic shock. Guidelines based on patient’s unique set of clinical variables will help a clinician in the process of decision making of suitable treatment for the particular patient. Therefore, biomarkers for sepsis diagnosis with a reasonable sensitivity and specificity are a requirement in ICU settings, as a guideline for the treatment. Moreover, the biomarker should also allow availability in real-time and prediction of sepsis progression to avoid delay in treatment and worsen the patient condition.
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spelling UMPir115752019-07-17T02:52:21Z http://umpir.ump.edu.my/id/eprint/11575/ Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network F. M., Suhaimi J. G., Chase G. M., Shaw Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak TJ Mechanical engineering and machinery Early treatment of sepsis can reduce mortality and improve a patient condition. However, the lack of clear information and accurate methods of diagnosing sepsis at an early stage makes it become a significant challenge. The decision to start, continue or stop antimicrobial therapy is normally base on clinical judgment since blood cultures will be negative in the majority of cases of septic shock or sepsis. However, clinical guidelines are still required to provide guidance for the clinician caring for a patient with severe sepsis or septic shock. Guidelines based on patient’s unique set of clinical variables will help a clinician in the process of decision making of suitable treatment for the particular patient. Therefore, biomarkers for sepsis diagnosis with a reasonable sensitivity and specificity are a requirement in ICU settings, as a guideline for the treatment. Moreover, the biomarker should also allow availability in real-time and prediction of sepsis progression to avoid delay in treatment and worsen the patient condition. Springer Fatimah, Ibrahim Juliana, Usman Mas Sahidayana, Mokhtar Mohd Yazed, Ahmad 2016 Book Chapter PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/11575/1/Prediction%20of%20Sepsis%20Progression%20in%20Critical%20Illness%20Using%20Artificial%20Neural%20Network.pdf F. M., Suhaimi and J. G., Chase and G. M., Shaw and Ummu Kulthum, Jamaludin and Normy Norfiza, A. Razak (2016) Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network. In: International Conference for Innovation in Biomedical Engineering and Life Sciences. IFMBE Proceedings, 56 . Springer, Singapore, pp. 127-132. ISBN 978-981-10-0265-6 (print); 978-981-10-0266-3 (online) http://dx.doi.org/10.1007/978-981-10-0266-3_26 DOI: 10.1007/978-981-10-0266-3_26
spellingShingle TJ Mechanical engineering and machinery
F. M., Suhaimi
J. G., Chase
G. M., Shaw
Ummu Kulthum, Jamaludin
Normy Norfiza, A. Razak
Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network
title Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network
title_full Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network
title_fullStr Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network
title_full_unstemmed Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network
title_short Prediction of Sepsis Progression in Critical Illness Using Artificial Neural Network
title_sort prediction of sepsis progression in critical illness using artificial neural network
topic TJ Mechanical engineering and machinery
url http://umpir.ump.edu.my/id/eprint/11575/1/Prediction%20of%20Sepsis%20Progression%20in%20Critical%20Illness%20Using%20Artificial%20Neural%20Network.pdf
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