Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM)

Fabrication of silver nanoparticles-loaded chitosan-polylactic acid based biofilms was successfully employed for investigating the optimal of mechanical properties (i.e. tensile strength and elongation at break) of biofilms using central composite design (CCD), response surface methodology (RSM). In...

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Main Authors: A., Shaari, Mazrul Nizam, Abu Seman, C. K. M., Faizal
Format: Conference or Workshop Item
Language:English
English
Published: EDP Sciences 2017
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/16436/1/Optimization%20of%20Mechanical%20Properties%20of%20Silver%20Nanoparticles%20%28AgNPS%29-Loaded%20Chitosan-Polylactic%20Acid%20%28PLA%29%20Biofilms%20by%20Using%20Response%20Surface%20Methodology%20%28RSM%29.pdf
http://umpir.ump.edu.my/id/eprint/16436/3/Optimization%20of%20Mechanical%20Properties%20of%20Silver%20Nanoparticles%20%28AgNPS%29-Loaded%20Chitosan-Polylactic%20Acid%20%28PLA%29%20Biofilms%20by%20Using%20Response%20Surface%20Methodology%20%28RSM%29%201.pdf
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author A., Shaari
Mazrul Nizam, Abu Seman
C. K. M., Faizal
author_facet A., Shaari
Mazrul Nizam, Abu Seman
C. K. M., Faizal
author_sort A., Shaari
collection UMP
description Fabrication of silver nanoparticles-loaded chitosan-polylactic acid based biofilms was successfully employed for investigating the optimal of mechanical properties (i.e. tensile strength and elongation at break) of biofilms using central composite design (CCD), response surface methodology (RSM). In this study, only two factors that influences the biofilm mechanical properties were selected namely concentration of polyethelene glycol 400 (PEG) and percentage volume of polylactic acid (PLA)/chitosan. Analysis of results was performed by using response surface methodology (RSM) to avoid the traditional one-factor-at-a-time experiments. Common statistical tools such as analysis of variance (ANOVA) and response surface plot were used to determine the optimal tensile strength and elongation at break responses. Central composite design (CCD) builds a response surface for mechanical properties of biofilms optimization. From the results of statistical analysis, it could be concluded that the optimal conditions for mechanical properties of biofilms were 7.93% w/w concentration of polyethylene glycol (PEG) and 28.79%/71.21% percentage volume of polylactic acid (PLA)/chitosan. At this optimum stage, 7.99 MPa of tensile strength and 32.6 % elongation at break were obtained. Then, results of verification process have shown that the percentage errors are 2.08% for tensile strength and 3.89% elongation at break, respectively.
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spelling UMPir164362018-01-09T07:02:18Z http://umpir.ump.edu.my/id/eprint/16436/ Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM) A., Shaari Mazrul Nizam, Abu Seman C. K. M., Faizal T Technology (General) TP Chemical technology Fabrication of silver nanoparticles-loaded chitosan-polylactic acid based biofilms was successfully employed for investigating the optimal of mechanical properties (i.e. tensile strength and elongation at break) of biofilms using central composite design (CCD), response surface methodology (RSM). In this study, only two factors that influences the biofilm mechanical properties were selected namely concentration of polyethelene glycol 400 (PEG) and percentage volume of polylactic acid (PLA)/chitosan. Analysis of results was performed by using response surface methodology (RSM) to avoid the traditional one-factor-at-a-time experiments. Common statistical tools such as analysis of variance (ANOVA) and response surface plot were used to determine the optimal tensile strength and elongation at break responses. Central composite design (CCD) builds a response surface for mechanical properties of biofilms optimization. From the results of statistical analysis, it could be concluded that the optimal conditions for mechanical properties of biofilms were 7.93% w/w concentration of polyethylene glycol (PEG) and 28.79%/71.21% percentage volume of polylactic acid (PLA)/chitosan. At this optimum stage, 7.99 MPa of tensile strength and 32.6 % elongation at break were obtained. Then, results of verification process have shown that the percentage errors are 2.08% for tensile strength and 3.89% elongation at break, respectively. EDP Sciences 2017-05 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/16436/1/Optimization%20of%20Mechanical%20Properties%20of%20Silver%20Nanoparticles%20%28AgNPS%29-Loaded%20Chitosan-Polylactic%20Acid%20%28PLA%29%20Biofilms%20by%20Using%20Response%20Surface%20Methodology%20%28RSM%29.pdf application/pdf en http://umpir.ump.edu.my/id/eprint/16436/3/Optimization%20of%20Mechanical%20Properties%20of%20Silver%20Nanoparticles%20%28AgNPS%29-Loaded%20Chitosan-Polylactic%20Acid%20%28PLA%29%20Biofilms%20by%20Using%20Response%20Surface%20Methodology%20%28RSM%29%201.pdf A., Shaari and Mazrul Nizam, Abu Seman and C. K. M., Faizal (2017) Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM). In: 2nd International Conference on Materials Science and Nanotechnology (ICMSNT 2017) and 2nd International Symposium on Material Science and Technology (ISMST 2017) , 19-22 April 201 , Auckland, New Zealand. pp. 1-6., 109 (01001). ISSN 2261-236X https://www.matec-conferences.org/articles/matecconf/pdf/2017/23/matecconf_icmsnt2017_01001.pdf DOI: 10.1051/matecconf/20171090100 ICMSNT 2017 1
spellingShingle T Technology (General)
TP Chemical technology
A., Shaari
Mazrul Nizam, Abu Seman
C. K. M., Faizal
Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM)
title Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM)
title_full Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM)
title_fullStr Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM)
title_full_unstemmed Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM)
title_short Optimization of Mechanical Properties of Silver Nanoparticles (AgNPS)-Loaded Chitosan/Polylactic Acid (PLA) Biofilms by Using Response Surface Methodology (RSM)
title_sort optimization of mechanical properties of silver nanoparticles agnps loaded chitosan polylactic acid pla biofilms by using response surface methodology rsm
topic T Technology (General)
TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/16436/1/Optimization%20of%20Mechanical%20Properties%20of%20Silver%20Nanoparticles%20%28AgNPS%29-Loaded%20Chitosan-Polylactic%20Acid%20%28PLA%29%20Biofilms%20by%20Using%20Response%20Surface%20Methodology%20%28RSM%29.pdf
http://umpir.ump.edu.my/id/eprint/16436/3/Optimization%20of%20Mechanical%20Properties%20of%20Silver%20Nanoparticles%20%28AgNPS%29-Loaded%20Chitosan-Polylactic%20Acid%20%28PLA%29%20Biofilms%20by%20Using%20Response%20Surface%20Methodology%20%28RSM%29%201.pdf
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