Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells
Researchers nowadays prefer biochip technology platform as a medium for conducting the analysis of biological cells where appropriate manipulation techniques like trapping, screening and sorting in a few seconds are required to perform biological cells analysis. Non-uniform AC electric field is requ...
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| Format: | Conference or Workshop Item |
| Language: | English English |
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IEEE
2017
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| Online Access: | http://umpir.ump.edu.my/id/eprint/18226/1/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells.pdf http://umpir.ump.edu.my/id/eprint/18226/5/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells%201.pdf |
| _version_ | 1796992231423344640 |
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| author | Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri |
| author_facet | Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri |
| author_sort | Siti Nursyahirah, Ahmad Latfi |
| collection | UMP |
| description | Researchers nowadays prefer biochip technology platform as a medium for conducting the analysis of biological cells where appropriate manipulation techniques like trapping, screening and sorting in a few seconds are required to perform biological cells analysis. Non-uniform AC electric field is required for dielectrophoresis force (DEP) to implement manipulation technique, where the non-uniform AC is generated by microelectrodes designed. The current design has a limitation in term of electric field distribution pattern generated. Thus, ring microarray microelectrode pattern was designed and simulated using COMSOL Multiphysics 4.4 software for implementing one of the main objectives of this study, which is to investigate the electric field distribution resulting from the microelectrodes designed. To optimize the generated DEP force for manipulating biological cells, electric field simulation is very important. The electric field simulation performed by altering some microelectrode geometric design parameters such as the microelectrodes length and the distance between the microelectrodes and the microcavity. The simulation has been shown in this paper. This is intended to simulate the effect of an electric field that results when there are any changes to the geometric design of microelectrodes. Based on the simulation that has been done, the results show the distance between the microelectrodes and microcavity provide more impact in electric field distribution strength compared to the change of the microelectrodes size. |
| first_indexed | 2024-03-06T12:17:02Z |
| format | Conference or Workshop Item |
| id | UMPir18226 |
| institution | Universiti Malaysia Pahang |
| language | English English |
| last_indexed | 2024-03-06T12:17:02Z |
| publishDate | 2017 |
| publisher | IEEE |
| record_format | dspace |
| spelling | UMPir182262018-07-18T06:52:54Z http://umpir.ump.edu.my/id/eprint/18226/ Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri TK Electrical engineering. Electronics Nuclear engineering Researchers nowadays prefer biochip technology platform as a medium for conducting the analysis of biological cells where appropriate manipulation techniques like trapping, screening and sorting in a few seconds are required to perform biological cells analysis. Non-uniform AC electric field is required for dielectrophoresis force (DEP) to implement manipulation technique, where the non-uniform AC is generated by microelectrodes designed. The current design has a limitation in term of electric field distribution pattern generated. Thus, ring microarray microelectrode pattern was designed and simulated using COMSOL Multiphysics 4.4 software for implementing one of the main objectives of this study, which is to investigate the electric field distribution resulting from the microelectrodes designed. To optimize the generated DEP force for manipulating biological cells, electric field simulation is very important. The electric field simulation performed by altering some microelectrode geometric design parameters such as the microelectrodes length and the distance between the microelectrodes and the microcavity. The simulation has been shown in this paper. This is intended to simulate the effect of an electric field that results when there are any changes to the geometric design of microelectrodes. Based on the simulation that has been done, the results show the distance between the microelectrodes and microcavity provide more impact in electric field distribution strength compared to the change of the microelectrodes size. IEEE 2017-04 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/18226/1/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells.pdf pdf en http://umpir.ump.edu.my/id/eprint/18226/5/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells%201.pdf Siti Nursyahirah, Ahmad Latfi and Fahmi, Samsuri (2017) Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells. In: 6th IEEE International Conference on Control System, Computing and Engineering (ICCSCE 2016) , 25-27 November 2016 , PARK ROYAL Penang Resort, Penang; Malaysia. pp. 79-84.. ISBN 978-150901178-0 https://ieeexplore.ieee.org/document/7893549/ |
| spellingShingle | TK Electrical engineering. Electronics Nuclear engineering Siti Nursyahirah, Ahmad Latfi Fahmi, Samsuri Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells |
| title | Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells |
| title_full | Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells |
| title_fullStr | Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells |
| title_full_unstemmed | Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells |
| title_short | Simulation of electric fields for the development of biochip for the purpose of manipulating biological cells |
| title_sort | simulation of electric fields for the development of biochip for the purpose of manipulating biological cells |
| topic | TK Electrical engineering. Electronics Nuclear engineering |
| url | http://umpir.ump.edu.my/id/eprint/18226/1/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells.pdf http://umpir.ump.edu.my/id/eprint/18226/5/Simulation%20of%20electric%20fields%20for%20the%20development%20of%20biochip%20for%20the%20purpose%20of%20manipulating%20biological%20cells%201.pdf |
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