Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs)

Glycosaminoglycans (GAGS) are polysaccharide composed of repeating disaccharide units either sulfated or non-sulfated monosaccharides of uronic acids and amino sugars which are structured alternately [1, 2]. As the sources of GAGs are mainly from the non-halal source and less extracted from hal...

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Main Authors: Marina, Mohd Sham, Nina Suhaity, Azmi
Format: Article
Language:English
Published: Research India Publication 2016
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/18786/1/Blue-spotted%20Stingray%20A%20promising%20source%20of%20potential%20GAGss.pdf
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author Marina, Mohd Sham
Nina Suhaity, Azmi
author_facet Marina, Mohd Sham
Nina Suhaity, Azmi
author_sort Marina, Mohd Sham
collection UMP
description Glycosaminoglycans (GAGS) are polysaccharide composed of repeating disaccharide units either sulfated or non-sulfated monosaccharides of uronic acids and amino sugars which are structured alternately [1, 2]. As the sources of GAGs are mainly from the non-halal source and less extracted from halal source especially from marine lives, thus this invention is likely conducted in order to find the new halal source of GAGs. The objectives of the study are to extract the GAGs from Blue-spotted Stingray and characterize the extracted GAGs by using Blyscan assay, FTIR and NMR. The Blue-spotted stingray shows high sulfated GAG content which is 7.58% from crude obtained. Carboxylate with sulfate and amine presende in FTIR spectra indicate that the sample is chondroitin sulfate. The presence of O-sulfated group and methyl group of GalNAc and GlcNAc in NMR spectra indicate the presence of chondroitin sulfate. From the results, it can be concluded that GAGs contained in Blue-spotted Stingray.
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spelling UMPir187862023-04-11T04:37:57Z http://umpir.ump.edu.my/id/eprint/18786/ Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs) Marina, Mohd Sham Nina Suhaity, Azmi Q Science (General) SH Aquaculture. Fisheries. Angling Glycosaminoglycans (GAGS) are polysaccharide composed of repeating disaccharide units either sulfated or non-sulfated monosaccharides of uronic acids and amino sugars which are structured alternately [1, 2]. As the sources of GAGs are mainly from the non-halal source and less extracted from halal source especially from marine lives, thus this invention is likely conducted in order to find the new halal source of GAGs. The objectives of the study are to extract the GAGs from Blue-spotted Stingray and characterize the extracted GAGs by using Blyscan assay, FTIR and NMR. The Blue-spotted stingray shows high sulfated GAG content which is 7.58% from crude obtained. Carboxylate with sulfate and amine presende in FTIR spectra indicate that the sample is chondroitin sulfate. The presence of O-sulfated group and methyl group of GalNAc and GlcNAc in NMR spectra indicate the presence of chondroitin sulfate. From the results, it can be concluded that GAGs contained in Blue-spotted Stingray. Research India Publication 2016 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/18786/1/Blue-spotted%20Stingray%20A%20promising%20source%20of%20potential%20GAGss.pdf Marina, Mohd Sham and Nina Suhaity, Azmi (2016) Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs). International Journal of Applied Chemistry, 12 (4). pp. 795-802. ISSN 0973-1792. (Published) https://www.ripublication.com/ijac16/ijacv12n4_29.pdf
spellingShingle Q Science (General)
SH Aquaculture. Fisheries. Angling
Marina, Mohd Sham
Nina Suhaity, Azmi
Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs)
title Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs)
title_full Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs)
title_fullStr Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs)
title_full_unstemmed Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs)
title_short Blue-spotted stingray : A promising source of beneficial glycosaminoglycans (GAGs)
title_sort blue spotted stingray a promising source of beneficial glycosaminoglycans gags
topic Q Science (General)
SH Aquaculture. Fisheries. Angling
url http://umpir.ump.edu.my/id/eprint/18786/1/Blue-spotted%20Stingray%20A%20promising%20source%20of%20potential%20GAGss.pdf
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