Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel
Bio-waste corn-cob cellulose supported poly(hydroxamic acid) palladium complex was synthesized and it is characterized using some different techniques such as FTIR, FESEM, HRTEM, EDX, XPS, UV–vis, TGA and ICP-AES analyses. The cellulose supported heterogeneous palladium complex showed high stability...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/19471/1/fist-2017-shaheen-Poly%28hydroxamic%20acid%29%20palladium%20catalyst%20for%20heck1.pdf |
| Summary: | Bio-waste corn-cob cellulose supported poly(hydroxamic acid) palladium complex was synthesized and it is characterized using some different techniques such as FTIR, FESEM, HRTEM, EDX, XPS, UV–vis, TGA and ICP-AES analyses. The cellulose supported heterogeneous palladium complex showed high stability and catalytic activity toward Mizoroki-Heck reaction of aryl/heteroaryl halides and arenediazonium tetrafluoroborate with a variety of olefins to give the corresponding coupling products in up to 97% yield. The palladium complex was also applied to the synthesis of Ozagrel a thromboxane A2-synthetase inhibitor
with excellent yield. The complex was separated from the reaction mixture by simple filtration and repeatedly used up to seven times without significant loss of its catalytic performance. |
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