Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel
Bio-waste corn-cob cellulose supported poly(hydroxamic acid) palladium complex was synthesized and it is characterized using some different techniques such as FTIR, FESEM, HRTEM, EDX, XPS, UV–vis, TGA and ICP-AES analyses. The cellulose supported heterogeneous palladium complex showed high stability...
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| Format: | Article |
| Language: | English |
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Elsevier
2017
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| Online Access: | http://umpir.ump.edu.my/id/eprint/19471/1/fist-2017-shaheen-Poly%28hydroxamic%20acid%29%20palladium%20catalyst%20for%20heck1.pdf |
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| author | Sarkar, Shaheen M. Lutfor, M. R. Chong, Kwok Feng M. M., Yusoff |
| author_facet | Sarkar, Shaheen M. Lutfor, M. R. Chong, Kwok Feng M. M., Yusoff |
| author_sort | Sarkar, Shaheen M. |
| collection | UMP |
| description | Bio-waste corn-cob cellulose supported poly(hydroxamic acid) palladium complex was synthesized and it is characterized using some different techniques such as FTIR, FESEM, HRTEM, EDX, XPS, UV–vis, TGA and ICP-AES analyses. The cellulose supported heterogeneous palladium complex showed high stability and catalytic activity toward Mizoroki-Heck reaction of aryl/heteroaryl halides and arenediazonium tetrafluoroborate with a variety of olefins to give the corresponding coupling products in up to 97% yield. The palladium complex was also applied to the synthesis of Ozagrel a thromboxane A2-synthetase inhibitor
with excellent yield. The complex was separated from the reaction mixture by simple filtration and repeatedly used up to seven times without significant loss of its catalytic performance. |
| first_indexed | 2024-03-06T12:19:44Z |
| format | Article |
| id | UMPir19471 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T12:19:44Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | UMPir194712018-05-18T07:36:15Z http://umpir.ump.edu.my/id/eprint/19471/ Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel Sarkar, Shaheen M. Lutfor, M. R. Chong, Kwok Feng M. M., Yusoff QD Chemistry Bio-waste corn-cob cellulose supported poly(hydroxamic acid) palladium complex was synthesized and it is characterized using some different techniques such as FTIR, FESEM, HRTEM, EDX, XPS, UV–vis, TGA and ICP-AES analyses. The cellulose supported heterogeneous palladium complex showed high stability and catalytic activity toward Mizoroki-Heck reaction of aryl/heteroaryl halides and arenediazonium tetrafluoroborate with a variety of olefins to give the corresponding coupling products in up to 97% yield. The palladium complex was also applied to the synthesis of Ozagrel a thromboxane A2-synthetase inhibitor with excellent yield. The complex was separated from the reaction mixture by simple filtration and repeatedly used up to seven times without significant loss of its catalytic performance. Elsevier 2017 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/19471/1/fist-2017-shaheen-Poly%28hydroxamic%20acid%29%20palladium%20catalyst%20for%20heck1.pdf Sarkar, Shaheen M. and Lutfor, M. R. and Chong, Kwok Feng and M. M., Yusoff (2017) Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel. Journal of Catalysis, 350. pp. 103-110. ISSN 0021-9517. (Published) https://doi.org/10.1016/j.jcat.2017.03.023 http://dx.doi.org/10.1016/j.jcat.2017.03.023 |
| spellingShingle | QD Chemistry Sarkar, Shaheen M. Lutfor, M. R. Chong, Kwok Feng M. M., Yusoff Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel |
| title | Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel |
| title_full | Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel |
| title_fullStr | Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel |
| title_full_unstemmed | Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel |
| title_short | Poly(hydroxamic acid) Palladium Catalyst for Heck Reactions and its Application in the Synthesis of Ozagrel |
| title_sort | poly hydroxamic acid palladium catalyst for heck reactions and its application in the synthesis of ozagrel |
| topic | QD Chemistry |
| url | http://umpir.ump.edu.my/id/eprint/19471/1/fist-2017-shaheen-Poly%28hydroxamic%20acid%29%20palladium%20catalyst%20for%20heck1.pdf |
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