Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction

Nutraceuticals and phytomedicines are largely used in pharmaceutical industry at this era. Phytomedicines are pharmaceuticals which made from plants which has significant property of treating some illnesses. Tongkat Ali, or eurycoma longifolia, is a traditional herb medicine used as aphrodisiac, gen...

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Main Authors: He, Yu Hai, Ahmad Ziad, Sulaiman
Format: Conference or Workshop Item
Language:English
Published: 2015
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/20458/1/fkksa-2015-yuhai-Optimization%20Of%20Eurycomanone%20Yield%20Using%20Response%20Surface.pdf
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author He, Yu Hai
Ahmad Ziad, Sulaiman
author_facet He, Yu Hai
Ahmad Ziad, Sulaiman
author_sort He, Yu Hai
collection UMP
description Nutraceuticals and phytomedicines are largely used in pharmaceutical industry at this era. Phytomedicines are pharmaceuticals which made from plants which has significant property of treating some illnesses. Tongkat Ali, or eurycoma longifolia, is a traditional herb medicine used as aphrodisiac, general tonic, anti-Malaria, and anti-Pyreti. Nowadays, Tongkat Ali has become known globally due to its ability to treat erectile dysfunction (ED) and to improve sexual desire. Eurycomanon is a very important quassinoids found in Tongkat Ali extract which has a potential to be developed as complementary for anti-cancer therapy. In this research, extraction of eurycomanone from tongkat ali was performed according response surface methodology. Optimization of eurycomanone yield was obtained through central composite design (CCD). The maximum eurycomanone amount which is 0.559% was obtained at solvent to raw material ratio of 28.8:1 g/g, duration of extraction of 3 hour, and 0.054-0.154 mm of raw material.
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spelling UMPir204582018-02-07T02:04:27Z http://umpir.ump.edu.my/id/eprint/20458/ Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction He, Yu Hai Ahmad Ziad, Sulaiman TP Chemical technology Nutraceuticals and phytomedicines are largely used in pharmaceutical industry at this era. Phytomedicines are pharmaceuticals which made from plants which has significant property of treating some illnesses. Tongkat Ali, or eurycoma longifolia, is a traditional herb medicine used as aphrodisiac, general tonic, anti-Malaria, and anti-Pyreti. Nowadays, Tongkat Ali has become known globally due to its ability to treat erectile dysfunction (ED) and to improve sexual desire. Eurycomanon is a very important quassinoids found in Tongkat Ali extract which has a potential to be developed as complementary for anti-cancer therapy. In this research, extraction of eurycomanone from tongkat ali was performed according response surface methodology. Optimization of eurycomanone yield was obtained through central composite design (CCD). The maximum eurycomanone amount which is 0.559% was obtained at solvent to raw material ratio of 28.8:1 g/g, duration of extraction of 3 hour, and 0.054-0.154 mm of raw material. 2015 Conference or Workshop Item NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/20458/1/fkksa-2015-yuhai-Optimization%20Of%20Eurycomanone%20Yield%20Using%20Response%20Surface.pdf He, Yu Hai and Ahmad Ziad, Sulaiman (2015) Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction. In: National Conference on Postgraduate Studies (NCON-PGR 2015) , 24-25 January 2015 , Kuantan, Pahang. pp. 1-20.. (Published)
spellingShingle TP Chemical technology
He, Yu Hai
Ahmad Ziad, Sulaiman
Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction
title Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction
title_full Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction
title_fullStr Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction
title_full_unstemmed Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction
title_short Optimization Of Eurycomanone Yield Using Response Surface Methodology By Water Extraction
title_sort optimization of eurycomanone yield using response surface methodology by water extraction
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/20458/1/fkksa-2015-yuhai-Optimization%20Of%20Eurycomanone%20Yield%20Using%20Response%20Surface.pdf
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