Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search
Mathematical models of metabolic processes are the cornerstone of computational systems biology. In model building, the task of parameter estimation is difficult due to the huge numbers of kinetics parameters involved. The common way of estimating the parameters is to formulate it as an optimization...
| Main Authors: | , , , , , , , |
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| Format: | Book Chapter |
| Language: | English English English |
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Springer Verlag
2019
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/22145/1/Parameter%20estimation%20of%20essential%20amino%20acids%20in%20Arabidopsis%20thaliana%20using%20hybrid%20of%20bees%20algorithm%20and%20harmony%20search.pdf http://umpir.ump.edu.my/id/eprint/22145/7/18.%20Parameter%20Estimation%20of%20Essential%20Amino%20Acids%20in%20Arabidopsis%20thaliana.pdf http://umpir.ump.edu.my/id/eprint/22145/8/18.1%20Parameter%20Estimation%20of%20Essential%20Amino%20Acids%20in%20Arabidopsis%20thaliana.pdf |
| _version_ | 1825812244546453504 |
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| author | Aw, Mei Yee Mohd Saberi, Mohamad Chong, Chuii Khim Safaai, Deris Muhammad Akmal, Remli Mohd Arfian, Ismail Corchado, Juan Manuel Omatu, Sigeru |
| author_facet | Aw, Mei Yee Mohd Saberi, Mohamad Chong, Chuii Khim Safaai, Deris Muhammad Akmal, Remli Mohd Arfian, Ismail Corchado, Juan Manuel Omatu, Sigeru |
| author_sort | Aw, Mei Yee |
| collection | UMP |
| description | Mathematical models of metabolic processes are the cornerstone of computational systems biology. In model building, the task of parameter estimation is difficult due to the huge numbers of kinetics parameters involved. The common way of estimating the parameters is to formulate it as an optimization problem. Global optimization methods can be applied by minimizing the distance between experimental data and predicted models. This paper proposes the Hybrid of Bees Algorithm and Harmony Search (BAHS) to estimate the kinetics parameters of essential amino acid production in the aspartate metabolism for Arabidopsis thaliana. The performance of the BAHS is evaluated and compared with other algorithms. The results show that BAHS performed better as it improved the performance of the original BA by 60%. Meanwhile, it takes less computational time to estimate the kinetics parameters of essential amino acid production for Arabidopsis thaliana. |
| first_indexed | 2024-03-06T12:26:17Z |
| format | Book Chapter |
| id | UMPir22145 |
| institution | Universiti Malaysia Pahang |
| language | English English English |
| last_indexed | 2024-03-06T12:26:17Z |
| publishDate | 2019 |
| publisher | Springer Verlag |
| record_format | dspace |
| spelling | UMPir221452019-05-15T04:27:30Z http://umpir.ump.edu.my/id/eprint/22145/ Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search Aw, Mei Yee Mohd Saberi, Mohamad Chong, Chuii Khim Safaai, Deris Muhammad Akmal, Remli Mohd Arfian, Ismail Corchado, Juan Manuel Omatu, Sigeru QA76 Computer software Mathematical models of metabolic processes are the cornerstone of computational systems biology. In model building, the task of parameter estimation is difficult due to the huge numbers of kinetics parameters involved. The common way of estimating the parameters is to formulate it as an optimization problem. Global optimization methods can be applied by minimizing the distance between experimental data and predicted models. This paper proposes the Hybrid of Bees Algorithm and Harmony Search (BAHS) to estimate the kinetics parameters of essential amino acid production in the aspartate metabolism for Arabidopsis thaliana. The performance of the BAHS is evaluated and compared with other algorithms. The results show that BAHS performed better as it improved the performance of the original BA by 60%. Meanwhile, it takes less computational time to estimate the kinetics parameters of essential amino acid production for Arabidopsis thaliana. Springer Verlag 2019 Book Chapter PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/22145/1/Parameter%20estimation%20of%20essential%20amino%20acids%20in%20Arabidopsis%20thaliana%20using%20hybrid%20of%20bees%20algorithm%20and%20harmony%20search.pdf pdf en http://umpir.ump.edu.my/id/eprint/22145/7/18.%20Parameter%20Estimation%20of%20Essential%20Amino%20Acids%20in%20Arabidopsis%20thaliana.pdf pdf en http://umpir.ump.edu.my/id/eprint/22145/8/18.1%20Parameter%20Estimation%20of%20Essential%20Amino%20Acids%20in%20Arabidopsis%20thaliana.pdf Aw, Mei Yee and Mohd Saberi, Mohamad and Chong, Chuii Khim and Safaai, Deris and Muhammad Akmal, Remli and Mohd Arfian, Ismail and Corchado, Juan Manuel and Omatu, Sigeru (2019) Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search. In: Practical Applications of Computational Biology and Bioinformatics, 12th International Conference. Advances in Intelligent Systems and Computing . Springer Verlag, Berlin, Germany, pp. 9-16. ISBN 978-3-319-98702-6 https://link.springer.com/chapter/10.1007/978-3-319-98702-6_2 DOI: https://doi.org/10.1007/978-3-319-98702-6_2 |
| spellingShingle | QA76 Computer software Aw, Mei Yee Mohd Saberi, Mohamad Chong, Chuii Khim Safaai, Deris Muhammad Akmal, Remli Mohd Arfian, Ismail Corchado, Juan Manuel Omatu, Sigeru Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search |
| title | Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search |
| title_full | Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search |
| title_fullStr | Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search |
| title_full_unstemmed | Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search |
| title_short | Parameter estimation of essential amino acids in Arabidopsis thaliana using hybrid of bees algorithm and harmony search |
| title_sort | parameter estimation of essential amino acids in arabidopsis thaliana using hybrid of bees algorithm and harmony search |
| topic | QA76 Computer software |
| url | http://umpir.ump.edu.my/id/eprint/22145/1/Parameter%20estimation%20of%20essential%20amino%20acids%20in%20Arabidopsis%20thaliana%20using%20hybrid%20of%20bees%20algorithm%20and%20harmony%20search.pdf http://umpir.ump.edu.my/id/eprint/22145/7/18.%20Parameter%20Estimation%20of%20Essential%20Amino%20Acids%20in%20Arabidopsis%20thaliana.pdf http://umpir.ump.edu.my/id/eprint/22145/8/18.1%20Parameter%20Estimation%20of%20Essential%20Amino%20Acids%20in%20Arabidopsis%20thaliana.pdf |
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