Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying

Vernonia amygdalina leaf has a significant importance in food and traditional medicine. It has been reported to possess various pharmacological effects. This study was carried out to investigate the influence of microwave-assisted extraction factors on the extraction from V. amygdalina leaves. The r...

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Main Authors: Alara, Oluwaseun Ruth, Nour, A. H., Siti Kholijah, Abdul Mudalip, Olalere, Olusegun Abayomi
Format: Article
Language:English
Published: Kowsarmedical 2018
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/23754/1/Effects_of_Microwave-Assisted_Extraction_Parameter.pdf
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author Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Olalere, Olusegun Abayomi
author_facet Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Olalere, Olusegun Abayomi
author_sort Alara, Oluwaseun Ruth
collection UMP
description Vernonia amygdalina leaf has a significant importance in food and traditional medicine. It has been reported to possess various pharmacological effects. This study was carried out to investigate the influence of microwave-assisted extraction factors on the extraction from V. amygdalina leaves. The results highlighted that an increase in temperature deteriorated the yields of V. amygdalina leaf. Thus, shade-dried samples gave the highest yields at the irradiation times of 10 and 2 min, microwave power of 500 and 600W, the temperature of 100 and 80°C, the feed-to-solvent ratio of 1:10, and ethanol concentration of 60% v/v using water and ethanol as the extracting solvents, respectively. Likewise, the antioxidant assay resulted in IC50 values of 260_1.1 _g/mL DPPH and 149.78_0.81_g/mL ABTS for water and 204_0.92_g/mL DPPH and 31.17_1.4_g/mL ABTS for ethanol. Therefore, the synergistic mechanism of mass and heat transfer may be accounted for the accelerated extraction due to microwave.
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spelling UMPir237542019-09-10T04:05:03Z http://umpir.ump.edu.my/id/eprint/23754/ Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying Alara, Oluwaseun Ruth Nour, A. H. Siti Kholijah, Abdul Mudalip Olalere, Olusegun Abayomi TJ Mechanical engineering and machinery Vernonia amygdalina leaf has a significant importance in food and traditional medicine. It has been reported to possess various pharmacological effects. This study was carried out to investigate the influence of microwave-assisted extraction factors on the extraction from V. amygdalina leaves. The results highlighted that an increase in temperature deteriorated the yields of V. amygdalina leaf. Thus, shade-dried samples gave the highest yields at the irradiation times of 10 and 2 min, microwave power of 500 and 600W, the temperature of 100 and 80°C, the feed-to-solvent ratio of 1:10, and ethanol concentration of 60% v/v using water and ethanol as the extracting solvents, respectively. Likewise, the antioxidant assay resulted in IC50 values of 260_1.1 _g/mL DPPH and 149.78_0.81_g/mL ABTS for water and 204_0.92_g/mL DPPH and 31.17_1.4_g/mL ABTS for ethanol. Therefore, the synergistic mechanism of mass and heat transfer may be accounted for the accelerated extraction due to microwave. Kowsarmedical 2018 Article NonPeerReviewed pdf en cc_by_nc_4 http://umpir.ump.edu.my/id/eprint/23754/1/Effects_of_Microwave-Assisted_Extraction_Parameter.pdf Alara, Oluwaseun Ruth and Nour, A. H. and Siti Kholijah, Abdul Mudalip and Olalere, Olusegun Abayomi (2018) Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying. Jundishapur Journal of Natural Pharmaceutical Products. pp. 1-11. ISSN 1735-7780. (In Press / Online First) (In Press / Online First) http://jjnpp.com/en/articles/57620.html
spellingShingle TJ Mechanical engineering and machinery
Alara, Oluwaseun Ruth
Nour, A. H.
Siti Kholijah, Abdul Mudalip
Olalere, Olusegun Abayomi
Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying
title Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying
title_full Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying
title_fullStr Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying
title_full_unstemmed Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying
title_short Effects of Microwave-Assisted Extraction Parameters on the Recovery Yield and Total Phenolic Content of Vernonia amygdalina Leaf Extracts with Different Methods of Drying
title_sort effects of microwave assisted extraction parameters on the recovery yield and total phenolic content of vernonia amygdalina leaf extracts with different methods of drying
topic TJ Mechanical engineering and machinery
url http://umpir.ump.edu.my/id/eprint/23754/1/Effects_of_Microwave-Assisted_Extraction_Parameter.pdf
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