Computational model of left ventricle infarct remodelling during passive filling phase
Myocardial infarction causes part of the left ventricle muscle to not receive adequate oxygen supply and may cause muscle remodelling. Myocardium remodelling affects the blood pumping efficiency of the heart. In this paper, a model to describe myocardial remodelling during myocardial infarction is c...
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| Format: | Conference or Workshop Item |
| Language: | English English |
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2018
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| Online Access: | http://umpir.ump.edu.my/id/eprint/24008/1/27.1%20Computational%20model%20of%20left%20ventricle%20infarct%20remodelling.pdf http://umpir.ump.edu.my/id/eprint/24008/2/27.%20Computational%20model%20of%20left%20ventricle%20infarct%20remodelling.pdf |
| _version_ | 1796993199593488384 |
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| author | Mohd Jamil Mohamed, Mokhtarudin Abbas, Shabudin Dokos, Socrates |
| author_facet | Mohd Jamil Mohamed, Mokhtarudin Abbas, Shabudin Dokos, Socrates |
| author_sort | Mohd Jamil Mohamed, Mokhtarudin |
| collection | UMP |
| description | Myocardial infarction causes part of the left ventricle muscle to not receive adequate oxygen supply and may cause muscle remodelling. Myocardium remodelling affects the blood pumping efficiency of the heart. In this paper, a model to describe myocardial remodelling during myocardial infarction is coupled with myocardium material model through multiplicative decomposition of the deformation gradient. Passive filling simulations of a normal and abnormal left ventricles are done and it was found that the muscle stiffness is increased in abnormal LV, which is indicated by 0.19% difference in the end-diastolic volume. The tissue displacement is also distributed asymmetrically in the LV, which further affects the stiffness difference. Improvements of the simulation to include FSI and full cycle simulation can further enlight the capability of the model to predict myocardium infarct remodelling. |
| first_indexed | 2024-03-06T12:30:39Z |
| format | Conference or Workshop Item |
| id | UMPir24008 |
| institution | Universiti Malaysia Pahang |
| language | English English |
| last_indexed | 2024-03-06T12:30:39Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | UMPir240082019-02-12T04:25:54Z http://umpir.ump.edu.my/id/eprint/24008/ Computational model of left ventricle infarct remodelling during passive filling phase Mohd Jamil Mohamed, Mokhtarudin Abbas, Shabudin Dokos, Socrates TJ Mechanical engineering and machinery Myocardial infarction causes part of the left ventricle muscle to not receive adequate oxygen supply and may cause muscle remodelling. Myocardium remodelling affects the blood pumping efficiency of the heart. In this paper, a model to describe myocardial remodelling during myocardial infarction is coupled with myocardium material model through multiplicative decomposition of the deformation gradient. Passive filling simulations of a normal and abnormal left ventricles are done and it was found that the muscle stiffness is increased in abnormal LV, which is indicated by 0.19% difference in the end-diastolic volume. The tissue displacement is also distributed asymmetrically in the LV, which further affects the stiffness difference. Improvements of the simulation to include FSI and full cycle simulation can further enlight the capability of the model to predict myocardium infarct remodelling. 2018-09 Conference or Workshop Item NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/24008/1/27.1%20Computational%20model%20of%20left%20ventricle%20infarct%20remodelling.pdf pdf en http://umpir.ump.edu.my/id/eprint/24008/2/27.%20Computational%20model%20of%20left%20ventricle%20infarct%20remodelling.pdf Mohd Jamil Mohamed, Mokhtarudin and Abbas, Shabudin and Dokos, Socrates (2018) Computational model of left ventricle infarct remodelling during passive filling phase. In: IEEE-EMBS Conference on Biomedical Engineering And Sciences (IECBES 2018) , 3 - 6 December 2018 , Borneo Convention Centre Kuching, Sarawak, Malaysia. pp. 1-10.. (Unpublished) |
| spellingShingle | TJ Mechanical engineering and machinery Mohd Jamil Mohamed, Mokhtarudin Abbas, Shabudin Dokos, Socrates Computational model of left ventricle infarct remodelling during passive filling phase |
| title | Computational model of left ventricle infarct remodelling during passive filling phase |
| title_full | Computational model of left ventricle infarct remodelling during passive filling phase |
| title_fullStr | Computational model of left ventricle infarct remodelling during passive filling phase |
| title_full_unstemmed | Computational model of left ventricle infarct remodelling during passive filling phase |
| title_short | Computational model of left ventricle infarct remodelling during passive filling phase |
| title_sort | computational model of left ventricle infarct remodelling during passive filling phase |
| topic | TJ Mechanical engineering and machinery |
| url | http://umpir.ump.edu.my/id/eprint/24008/1/27.1%20Computational%20model%20of%20left%20ventricle%20infarct%20remodelling.pdf http://umpir.ump.edu.my/id/eprint/24008/2/27.%20Computational%20model%20of%20left%20ventricle%20infarct%20remodelling.pdf |
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