Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating
Nowadays, zinc oxide (ZnO) has attracted attention in research and development because of its remarkable antibacterial properties. Chitosan/ZnO nanoparticles were successfully synthesized via microwave heating. The objectives of this work were to investigate the effect of stabilizer, power heating a...
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| Format: | Article |
| Language: | English |
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Department of Chemical Engineering, Diponegoro University
2019
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| Online Access: | http://umpir.ump.edu.my/id/eprint/25043/1/Synthesis%20of%20chitosan_zinc%20oxide%20nanoparticles%20stabilized.pdf |
| _version_ | 1796993394946342912 |
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| author | Nurul Amira, Ahmad Yusof Norashikin, Mat Zain Norlin, Pauzi |
| author_facet | Nurul Amira, Ahmad Yusof Norashikin, Mat Zain Norlin, Pauzi |
| author_sort | Nurul Amira, Ahmad Yusof |
| collection | UMP |
| description | Nowadays, zinc oxide (ZnO) has attracted attention in research and development because of its remarkable antibacterial properties. Chitosan/ZnO nanoparticles were successfully synthesized via microwave heating. The objectives of this work were to investigate the effect of stabilizer, power heating and time heating on size of chitosan/ZnO nanoparticles and to determine antibacterial activity against pathogenic bacteria, where chitosan was used as a stabilizing agent. Chitosan/ZnO nanoparticles were analyzed by Fourier Transform Infra Red (FTIR), X-ray Diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM), and Zetasizer instrument. The power heating and time heating were varied from 400 to 800 Watt and 4 to 8 minutes, respectively. The presence of chitosan has role on preventing the nanoparticles from agglomeration by producing a milky solution of chitosan/ZnO nanoparticles without any suspensions. The increase of power and time heating improved the size of nanoparticles. The peak in FTIR spectrum at around 427 cm-1 was confirmed the existence of the ZnO phase. XRD patterns showed that the chitosan/ZnO nanoparticles materials were pure phase with average crystalline size is 130 nm. FESEM revealed that chitosan/ZnO nanoparticles were uniformly distributed with the mean value of size is 70 nm and spherical shaped. Further impact of power and time heating on the size of the chitosan/ZnO nanoparticles can be shown by a nanoparticles size distribution with the average of 30 to 90 nm. The results showed that chitosan/ZnO nanoparticles have displayed an antibacterial inhibition zone against Gram-positive S. aureus and Gram-negative E. coli which 16.0 and 13.3 mm, respectively. Chitosan/ZnO nanoparticles were synthesized in this work presented have potential application to prevent bacterial infections. |
| first_indexed | 2024-03-06T12:33:20Z |
| format | Article |
| id | UMPir25043 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T12:33:20Z |
| publishDate | 2019 |
| publisher | Department of Chemical Engineering, Diponegoro University |
| record_format | dspace |
| spelling | UMPir250432019-10-14T07:00:40Z http://umpir.ump.edu.my/id/eprint/25043/ Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating Nurul Amira, Ahmad Yusof Norashikin, Mat Zain Norlin, Pauzi QD Chemistry TP Chemical technology Nowadays, zinc oxide (ZnO) has attracted attention in research and development because of its remarkable antibacterial properties. Chitosan/ZnO nanoparticles were successfully synthesized via microwave heating. The objectives of this work were to investigate the effect of stabilizer, power heating and time heating on size of chitosan/ZnO nanoparticles and to determine antibacterial activity against pathogenic bacteria, where chitosan was used as a stabilizing agent. Chitosan/ZnO nanoparticles were analyzed by Fourier Transform Infra Red (FTIR), X-ray Diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM), and Zetasizer instrument. The power heating and time heating were varied from 400 to 800 Watt and 4 to 8 minutes, respectively. The presence of chitosan has role on preventing the nanoparticles from agglomeration by producing a milky solution of chitosan/ZnO nanoparticles without any suspensions. The increase of power and time heating improved the size of nanoparticles. The peak in FTIR spectrum at around 427 cm-1 was confirmed the existence of the ZnO phase. XRD patterns showed that the chitosan/ZnO nanoparticles materials were pure phase with average crystalline size is 130 nm. FESEM revealed that chitosan/ZnO nanoparticles were uniformly distributed with the mean value of size is 70 nm and spherical shaped. Further impact of power and time heating on the size of the chitosan/ZnO nanoparticles can be shown by a nanoparticles size distribution with the average of 30 to 90 nm. The results showed that chitosan/ZnO nanoparticles have displayed an antibacterial inhibition zone against Gram-positive S. aureus and Gram-negative E. coli which 16.0 and 13.3 mm, respectively. Chitosan/ZnO nanoparticles were synthesized in this work presented have potential application to prevent bacterial infections. Department of Chemical Engineering, Diponegoro University 2019-08 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/25043/1/Synthesis%20of%20chitosan_zinc%20oxide%20nanoparticles%20stabilized.pdf Nurul Amira, Ahmad Yusof and Norashikin, Mat Zain and Norlin, Pauzi (2019) Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating. Bulletin of Chemical Reaction Engineering & Catalysis, 14 (2). pp. 450-458. ISSN 1978-2993. (Published) https://doi.org/10.9767/bcrec.14.2.3319.450-458 https://doi.org/10.9767/bcrec.14.2.3319.450-458 |
| spellingShingle | QD Chemistry TP Chemical technology Nurul Amira, Ahmad Yusof Norashikin, Mat Zain Norlin, Pauzi Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating |
| title | Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating |
| title_full | Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating |
| title_fullStr | Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating |
| title_full_unstemmed | Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating |
| title_short | Synthesis of chitosan/zinc oxide nanoparticles stabilized by chitosan via microwave heating |
| title_sort | synthesis of chitosan zinc oxide nanoparticles stabilized by chitosan via microwave heating |
| topic | QD Chemistry TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/25043/1/Synthesis%20of%20chitosan_zinc%20oxide%20nanoparticles%20stabilized.pdf |
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