Presence of antibiotic resistant bacteria along the pharmaceuticals production line

The antimicrobial susceptibility of forty-five bacterial isolates obtained from different pharmaceutical raw materials of several companies in Cairo, Egypt during June to august, 2008 was determined using agar diffusion method. Only fourteen out of forty-five antibiotic resistant bacterial isolates...

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Main Authors: Makky, Essam A., Ibrahim, Mohamed M., El-Gamal, Mamdoh S.
Format: Article
Language:English
Published: Elsevier Ltd 2013
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/25374/1/Presence%20of%20antibiotic%20resistant%20bacteria%20along%20the%20pharmaceuticals%20production%20line.pdf
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author Makky, Essam A.
Ibrahim, Mohamed M.
El-Gamal, Mamdoh S.
author_facet Makky, Essam A.
Ibrahim, Mohamed M.
El-Gamal, Mamdoh S.
author_sort Makky, Essam A.
collection UMP
description The antimicrobial susceptibility of forty-five bacterial isolates obtained from different pharmaceutical raw materials of several companies in Cairo, Egypt during June to august, 2008 was determined using agar diffusion method. Only fourteen out of forty-five antibiotic resistant bacterial isolates were selected according to their sensitivity to equal or more than two antibiotics used. Isolates were subjected to antimicrobial susceptibility testing. The percent of resistance to seven antibiotics were Colis. (16.7%), Azithr. (78.6%), Oxytet. (0.0%), Amox. (21.4%), Kan. (42.8%), Cipro. (0.0%), and Spictin. (100.0%). Active potency of the raw materials was determined by incubating the drugs with and without microbes using HPLC and UV spectrophotometer. Among 14 selected isolates two were found to contain plasmids that are probably related to their drug resistance.
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spelling UMPir253742019-12-24T02:24:53Z http://umpir.ump.edu.my/id/eprint/25374/ Presence of antibiotic resistant bacteria along the pharmaceuticals production line Makky, Essam A. Ibrahim, Mohamed M. El-Gamal, Mamdoh S. Q Science (General) The antimicrobial susceptibility of forty-five bacterial isolates obtained from different pharmaceutical raw materials of several companies in Cairo, Egypt during June to august, 2008 was determined using agar diffusion method. Only fourteen out of forty-five antibiotic resistant bacterial isolates were selected according to their sensitivity to equal or more than two antibiotics used. Isolates were subjected to antimicrobial susceptibility testing. The percent of resistance to seven antibiotics were Colis. (16.7%), Azithr. (78.6%), Oxytet. (0.0%), Amox. (21.4%), Kan. (42.8%), Cipro. (0.0%), and Spictin. (100.0%). Active potency of the raw materials was determined by incubating the drugs with and without microbes using HPLC and UV spectrophotometer. Among 14 selected isolates two were found to contain plasmids that are probably related to their drug resistance. Elsevier Ltd 2013 Article PeerReviewed pdf en cc_by_nc_nd http://umpir.ump.edu.my/id/eprint/25374/1/Presence%20of%20antibiotic%20resistant%20bacteria%20along%20the%20pharmaceuticals%20production%20line.pdf Makky, Essam A. and Ibrahim, Mohamed M. and El-Gamal, Mamdoh S. (2013) Presence of antibiotic resistant bacteria along the pharmaceuticals production line. Procedia Engineering, 53. pp. 715-721. ISSN 1877-7058. (Published) https://doi.org/10.1016/j.proeng.2013.02.094 https://doi.org/10.1016/j.proeng.2013.02.094
spellingShingle Q Science (General)
Makky, Essam A.
Ibrahim, Mohamed M.
El-Gamal, Mamdoh S.
Presence of antibiotic resistant bacteria along the pharmaceuticals production line
title Presence of antibiotic resistant bacteria along the pharmaceuticals production line
title_full Presence of antibiotic resistant bacteria along the pharmaceuticals production line
title_fullStr Presence of antibiotic resistant bacteria along the pharmaceuticals production line
title_full_unstemmed Presence of antibiotic resistant bacteria along the pharmaceuticals production line
title_short Presence of antibiotic resistant bacteria along the pharmaceuticals production line
title_sort presence of antibiotic resistant bacteria along the pharmaceuticals production line
topic Q Science (General)
url http://umpir.ump.edu.my/id/eprint/25374/1/Presence%20of%20antibiotic%20resistant%20bacteria%20along%20the%20pharmaceuticals%20production%20line.pdf
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