Recent developments on (−)-colchicine derivatives: Synthesis and structure-activity relationship
(−)-Colchicine, an anti-microtubulin polymerization agent, is a valuable medication and the drug of choice for gout, Behçet’s disease and familial Mediterranean fever. It has a narrow therapeutic index due to its high toxicity towards normal cells. Nonetheless, numerous (−)-colchicine derivatives ha...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/26482/1/Recent%20developments%20on%20%28%E2%88%92%29-colchicine%20derivatives%20_%20synthesis%20and%20structure.pdf |