Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts
Therapeutic properties of the medicinal plant are due to the presence of phytochemical constituents. Garciniaatroviridis is locally known as ?asamgelugur? belongs to the Guttiferae family. Bioassay-guided solvent-solvent extraction method and yielded, hexane, dichloromethane, ethyl acetate, butanol,...
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| Format: | Article |
| Language: | English |
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IJAR
2018
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| Online Access: | http://umpir.ump.edu.my/id/eprint/27170/1/827_IJAR-25789.pdf |
| _version_ | 1825813117405233152 |
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| author | Nur Salsabila, Ahmad Roslan Zareen, Seema Normaiza, Z. Akhtar, Muhammad Nadeem |
| author_facet | Nur Salsabila, Ahmad Roslan Zareen, Seema Normaiza, Z. Akhtar, Muhammad Nadeem |
| author_sort | Nur Salsabila, Ahmad Roslan |
| collection | UMP |
| description | Therapeutic properties of the medicinal plant are due to the presence of phytochemical constituents. Garciniaatroviridis is locally known as ?asamgelugur? belongs to the Guttiferae family. Bioassay-guided solvent-solvent extraction method and yielded, hexane, dichloromethane, ethyl acetate, butanol, and methanolic extracts. These extracts were used to investigate the presence of phytochemicals. The preliminary phytochemical screening showed the existence of fixed oils and fats, carbohydrate, saponins, phenolic, flavonoids and anthraquinone glycosides in G. atroviridis roots. The chemical compositions were investigated by using Gas Chromatography-Mass Spectroscopy (GC-MS). Major compound identified in hexane, DCM, EA, BuOH and methanolic extracts was (Z)-13-docosenoic acid methyl ester (24.32%), ethyl-9-hexadecenoate (6.36%),bis(1,3-diisopropylcyclopentadienyl) (12.09%), 2-methyl-2-phenyl- 1,3-dioxolane (2.34%) and furfural (33.55%) respectively. The antibacterial and antioxidant activities of the extracts were investigated. The methanolic crude extract exhibited resistance towards both bacteria tested; Bacillus subtilisand Escherichia coli, thus suggesting its antibacterial activity. |
| first_indexed | 2024-03-06T12:39:16Z |
| format | Article |
| id | UMPir27170 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T12:39:16Z |
| publishDate | 2018 |
| publisher | IJAR |
| record_format | dspace |
| spelling | UMPir271702020-01-17T04:03:40Z http://umpir.ump.edu.my/id/eprint/27170/ Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts Nur Salsabila, Ahmad Roslan Zareen, Seema Normaiza, Z. Akhtar, Muhammad Nadeem QD Chemistry Therapeutic properties of the medicinal plant are due to the presence of phytochemical constituents. Garciniaatroviridis is locally known as ?asamgelugur? belongs to the Guttiferae family. Bioassay-guided solvent-solvent extraction method and yielded, hexane, dichloromethane, ethyl acetate, butanol, and methanolic extracts. These extracts were used to investigate the presence of phytochemicals. The preliminary phytochemical screening showed the existence of fixed oils and fats, carbohydrate, saponins, phenolic, flavonoids and anthraquinone glycosides in G. atroviridis roots. The chemical compositions were investigated by using Gas Chromatography-Mass Spectroscopy (GC-MS). Major compound identified in hexane, DCM, EA, BuOH and methanolic extracts was (Z)-13-docosenoic acid methyl ester (24.32%), ethyl-9-hexadecenoate (6.36%),bis(1,3-diisopropylcyclopentadienyl) (12.09%), 2-methyl-2-phenyl- 1,3-dioxolane (2.34%) and furfural (33.55%) respectively. The antibacterial and antioxidant activities of the extracts were investigated. The methanolic crude extract exhibited resistance towards both bacteria tested; Bacillus subtilisand Escherichia coli, thus suggesting its antibacterial activity. IJAR 2018 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/27170/1/827_IJAR-25789.pdf Nur Salsabila, Ahmad Roslan and Zareen, Seema and Normaiza, Z. and Akhtar, Muhammad Nadeem (2018) Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts. International Journal of Advanced Research, 7 (1). pp. 53-61. ISSN 2320-5407. (Published) https://doi.org/10.21474/IJAR01/8295 https://doi.org/10.21474/IJAR01/8295 |
| spellingShingle | QD Chemistry Nur Salsabila, Ahmad Roslan Zareen, Seema Normaiza, Z. Akhtar, Muhammad Nadeem Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts |
| title | Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts |
| title_full | Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts |
| title_fullStr | Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts |
| title_full_unstemmed | Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts |
| title_short | Preliminary phytochemical screening, GC-MS profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts |
| title_sort | preliminary phytochemical screening gc ms profiling and in vitro evaluation of biological activities of garcinia atroviridis root extracts |
| topic | QD Chemistry |
| url | http://umpir.ump.edu.my/id/eprint/27170/1/827_IJAR-25789.pdf |
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