A significant review on beam optimization for boron neutron capture therapy

The thermal column at the TRIGA PUSPATI (RTP) research reactor can produce thermal neutron. However, the optimization on the thermal neutron flux produced should be performed to gain a sufficient thermal neutron for boron neutron capture therapy purpose. Thus, the objective of this review is to opti...

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Main Authors: S., Shalbi, Norazlianie, Sazali, W. N. W., Salleh
Format: Conference or Workshop Item
Language:English
Published: IOP Publishing 2020
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/28074/7/A%20significant%20review%20on%20beam%20optimization%20for%20boron%20neutron.pdf
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author S., Shalbi
Norazlianie, Sazali
W. N. W., Salleh
author_facet S., Shalbi
Norazlianie, Sazali
W. N. W., Salleh
author_sort S., Shalbi
collection UMP
description The thermal column at the TRIGA PUSPATI (RTP) research reactor can produce thermal neutron. However, the optimization on the thermal neutron flux produced should be performed to gain a sufficient thermal neutron for boron neutron capture therapy purpose. Thus, the objective of this review is to optimize the thermal neutron flux by designing the collimator with different materials at the thermal column. In order to fulfil the requirement, set by the IAEA standard, the study of BNCT around the world was being reviewed to study the suitable measurement, material, design, and modification for BNCT at the thermal column of TRIGA MARK-II, Malaysia. Initially, the BNCT mechanisms and history was review. Then, this paper review on the design and modifications for BNCT purpose around the world. Based on this review, suitable material and design can be used for the BNCT in Malaysia. Moreover, this paper also reviews the current status of BNCT at the RTP with the measurement of the thermal neutron flux was conducted along the thermal column at 250 kW. The thermal column of RTP was divided into 3 phases (Phase 1, Phase 2 and Phase 3) so that an accurate measurement can be obtained by using gold foil activation method. This value was used as a benchmark for the neutron flux produced from the thermal column. The collimator was designed using different types of materials, and their characteristic towards gamma and neutron flux was investigated. The reviewed demonstrated that the final thermal neutron flux produced was significantly for BNCT purpose. Lastly, this paper recommends the future research can be conducted on BNCT at RTP.
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spelling UMPir280742020-04-30T01:07:43Z http://umpir.ump.edu.my/id/eprint/28074/ A significant review on beam optimization for boron neutron capture therapy S., Shalbi Norazlianie, Sazali W. N. W., Salleh Q Science (General) TP Chemical technology The thermal column at the TRIGA PUSPATI (RTP) research reactor can produce thermal neutron. However, the optimization on the thermal neutron flux produced should be performed to gain a sufficient thermal neutron for boron neutron capture therapy purpose. Thus, the objective of this review is to optimize the thermal neutron flux by designing the collimator with different materials at the thermal column. In order to fulfil the requirement, set by the IAEA standard, the study of BNCT around the world was being reviewed to study the suitable measurement, material, design, and modification for BNCT at the thermal column of TRIGA MARK-II, Malaysia. Initially, the BNCT mechanisms and history was review. Then, this paper review on the design and modifications for BNCT purpose around the world. Based on this review, suitable material and design can be used for the BNCT in Malaysia. Moreover, this paper also reviews the current status of BNCT at the RTP with the measurement of the thermal neutron flux was conducted along the thermal column at 250 kW. The thermal column of RTP was divided into 3 phases (Phase 1, Phase 2 and Phase 3) so that an accurate measurement can be obtained by using gold foil activation method. This value was used as a benchmark for the neutron flux produced from the thermal column. The collimator was designed using different types of materials, and their characteristic towards gamma and neutron flux was investigated. The reviewed demonstrated that the final thermal neutron flux produced was significantly for BNCT purpose. Lastly, this paper recommends the future research can be conducted on BNCT at RTP. IOP Publishing 2020 Conference or Workshop Item PeerReviewed pdf en cc_by http://umpir.ump.edu.my/id/eprint/28074/7/A%20significant%20review%20on%20beam%20optimization%20for%20boron%20neutron.pdf S., Shalbi and Norazlianie, Sazali and W. N. W., Salleh (2020) A significant review on beam optimization for boron neutron capture therapy. In: IOP Conference Series: Materials Science and Engineering; Energy Security and Chemical Engineering Congress (ESChE) 2019 , 17-19 July 2019 , Kuala Lumpur, Malaysia. pp. 1-19., 736 (062021). ISSN 1757-8981 (Print), 1757-899X (Online) https://doi.org/10.1088/1757-899X/736/6/062021
spellingShingle Q Science (General)
TP Chemical technology
S., Shalbi
Norazlianie, Sazali
W. N. W., Salleh
A significant review on beam optimization for boron neutron capture therapy
title A significant review on beam optimization for boron neutron capture therapy
title_full A significant review on beam optimization for boron neutron capture therapy
title_fullStr A significant review on beam optimization for boron neutron capture therapy
title_full_unstemmed A significant review on beam optimization for boron neutron capture therapy
title_short A significant review on beam optimization for boron neutron capture therapy
title_sort significant review on beam optimization for boron neutron capture therapy
topic Q Science (General)
TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/28074/7/A%20significant%20review%20on%20beam%20optimization%20for%20boron%20neutron.pdf
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