Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications
The development of hydrodynamic-based microfluidic biochips has been increasing over the years. In this technique, the cells or particles are trapped in a particular region for single cell analysis (SCA) usually without any application of external force fields such as optical, electrical, magnetic o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Royal Society of Chemistry
2017
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/29118/1/Microfluidic%20hydrodynamic%20trapping%20for%20single%20cell%20analysis.pdf |
| _version_ | 1796994194946916352 |
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| author | Vigneswaran, Narayanamurthy Nagarajan, Sairam Al'aina Yuhainis, Firus Khan Fahmi, Samsuri Sridhar, T. M. |
| author_facet | Vigneswaran, Narayanamurthy Nagarajan, Sairam Al'aina Yuhainis, Firus Khan Fahmi, Samsuri Sridhar, T. M. |
| author_sort | Vigneswaran, Narayanamurthy |
| collection | UMP |
| description | The development of hydrodynamic-based microfluidic biochips has been increasing over the years. In this technique, the cells or particles are trapped in a particular region for single cell analysis (SCA) usually without any application of external force fields such as optical, electrical, magnetic or acoustic. There is a need to explore the insights of SCA in the cell's natural state and development of these techniques is highly essential for that study. Researchers have highlighted the vast potential field that needs to be explored to develop biochip devices to suit market/researcher demands. Hydrodynamic microfluidics facilitates the development of passive lab-on-chip applications. This review gives an account of the recent advances in this field, along with their mechanisms, methods and applications. |
| first_indexed | 2024-03-06T12:44:30Z |
| format | Article |
| id | UMPir29118 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T12:44:30Z |
| publishDate | 2017 |
| publisher | Royal Society of Chemistry |
| record_format | dspace |
| spelling | UMPir291182022-11-07T07:37:50Z http://umpir.ump.edu.my/id/eprint/29118/ Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications Vigneswaran, Narayanamurthy Nagarajan, Sairam Al'aina Yuhainis, Firus Khan Fahmi, Samsuri Sridhar, T. M. QC Physics T Technology (General) TK Electrical engineering. Electronics Nuclear engineering The development of hydrodynamic-based microfluidic biochips has been increasing over the years. In this technique, the cells or particles are trapped in a particular region for single cell analysis (SCA) usually without any application of external force fields such as optical, electrical, magnetic or acoustic. There is a need to explore the insights of SCA in the cell's natural state and development of these techniques is highly essential for that study. Researchers have highlighted the vast potential field that needs to be explored to develop biochip devices to suit market/researcher demands. Hydrodynamic microfluidics facilitates the development of passive lab-on-chip applications. This review gives an account of the recent advances in this field, along with their mechanisms, methods and applications. Royal Society of Chemistry 2017-07-07 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/29118/1/Microfluidic%20hydrodynamic%20trapping%20for%20single%20cell%20analysis.pdf Vigneswaran, Narayanamurthy and Nagarajan, Sairam and Al'aina Yuhainis, Firus Khan and Fahmi, Samsuri and Sridhar, T. M. (2017) Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications. Analytical Methods, 9 (25). pp. 3751-3772. ISSN 1759-9660 (print); 1759-9679 (online). (Published) https://doi.org/10.1039/c7ay00656j https://doi.org/10.1039/c7ay00656j |
| spellingShingle | QC Physics T Technology (General) TK Electrical engineering. Electronics Nuclear engineering Vigneswaran, Narayanamurthy Nagarajan, Sairam Al'aina Yuhainis, Firus Khan Fahmi, Samsuri Sridhar, T. M. Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications |
| title | Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications |
| title_full | Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications |
| title_fullStr | Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications |
| title_full_unstemmed | Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications |
| title_short | Microfluidic hydrodynamic trapping for single cell analysis: mechanisms, methods and applications |
| title_sort | microfluidic hydrodynamic trapping for single cell analysis mechanisms methods and applications |
| topic | QC Physics T Technology (General) TK Electrical engineering. Electronics Nuclear engineering |
| url | http://umpir.ump.edu.my/id/eprint/29118/1/Microfluidic%20hydrodynamic%20trapping%20for%20single%20cell%20analysis.pdf |
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