Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms
The aim of the present study was to evaluate the therapeutic properties of selected fern, Chelianthusalbomarginata and to identify its functional compounds. The methanolic fern-extract (MFE) of these ferns was assessed for anti-bacterial activities by measuring inhibition zones against a panel of pa...
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| Format: | Article |
| Language: | English |
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IIUM, Malaysia
2017
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| Online Access: | http://umpir.ump.edu.my/id/eprint/29770/1/Anti-lipolytic%20activity%20and%20phytochemical%20screening%20of%20Chelianthesalbomarginata.pdf |
| _version_ | 1796994306868772864 |
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| author | Jarial, Rini Singh, Lakhveer Zularisam, A. W. Kanwar, S. S. |
| author_facet | Jarial, Rini Singh, Lakhveer Zularisam, A. W. Kanwar, S. S. |
| author_sort | Jarial, Rini |
| collection | UMP |
| description | The aim of the present study was to evaluate the therapeutic properties of selected fern, Chelianthusalbomarginata and to identify its functional compounds. The methanolic fern-extract (MFE) of these ferns was assessed for anti-bacterial activities by measuring inhibition zones against a panel of pathogenic bacterial strains using agar diffusion method. MFE at a concentration of 25 μg/ml showed marked anti-bacterial activity against all bacterial strains (6-23mm zone of inhibition) and was maximum against Enterobacter sp (23 mm). In addition, the MFE of C. albomarginata had the best MIC values of 2.25µg/ml against S. aureus and Enterobacter sp., respectively. The MFE also possessed good anti-lipolytic activity (66.5%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (79%). This result showed that MFE of C. albomarginata under optimal concentration is not only a potent source of natural anti-oxidants and anti-bacterial activity but also possesses efficient cholesterol degradation and anti-lipolytic activities, that is to be beneficial in the body weight management. |
| first_indexed | 2024-03-06T12:46:02Z |
| format | Article |
| id | UMPir29770 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T12:46:02Z |
| publishDate | 2017 |
| publisher | IIUM, Malaysia |
| record_format | dspace |
| spelling | UMPir297702022-11-10T01:48:17Z http://umpir.ump.edu.my/id/eprint/29770/ Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms Jarial, Rini Singh, Lakhveer Zularisam, A. W. Kanwar, S. S. TP Chemical technology The aim of the present study was to evaluate the therapeutic properties of selected fern, Chelianthusalbomarginata and to identify its functional compounds. The methanolic fern-extract (MFE) of these ferns was assessed for anti-bacterial activities by measuring inhibition zones against a panel of pathogenic bacterial strains using agar diffusion method. MFE at a concentration of 25 μg/ml showed marked anti-bacterial activity against all bacterial strains (6-23mm zone of inhibition) and was maximum against Enterobacter sp (23 mm). In addition, the MFE of C. albomarginata had the best MIC values of 2.25µg/ml against S. aureus and Enterobacter sp., respectively. The MFE also possessed good anti-lipolytic activity (66.5%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (79%). This result showed that MFE of C. albomarginata under optimal concentration is not only a potent source of natural anti-oxidants and anti-bacterial activity but also possesses efficient cholesterol degradation and anti-lipolytic activities, that is to be beneficial in the body weight management. IIUM, Malaysia 2017 Article PeerReviewed pdf en cc_by_4 http://umpir.ump.edu.my/id/eprint/29770/1/Anti-lipolytic%20activity%20and%20phytochemical%20screening%20of%20Chelianthesalbomarginata.pdf Jarial, Rini and Singh, Lakhveer and Zularisam, A. W. and Kanwar, S. S. (2017) Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms. IIUM Engineering Journal, 18 (2). pp. 56-62. ISSN 1511-788X. (Published) https://doi.org/10.31436/iiumej.v18i2.819 https://doi.org/10.31436/iiumej.v18i2.819 |
| spellingShingle | TP Chemical technology Jarial, Rini Singh, Lakhveer Zularisam, A. W. Kanwar, S. S. Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms |
| title | Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms |
| title_full | Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms |
| title_fullStr | Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms |
| title_full_unstemmed | Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms |
| title_short | Anti-lipolytic activity and phytochemical screening of Chelianthesalbomarginata against pathogenic microorganisms |
| title_sort | anti lipolytic activity and phytochemical screening of chelianthesalbomarginata against pathogenic microorganisms |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/29770/1/Anti-lipolytic%20activity%20and%20phytochemical%20screening%20of%20Chelianthesalbomarginata.pdf |
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