Design and optimization of a probiotic tablet for gastrointestinal tolerance by a simplex-centroid mixture.
In this study, a simplex-centroid mixture design using design of experiment (DOE) software was implemented to evaluate the effect of biopolymers as excipients, which are hydroxypropyl methylcellulose, and alginate, on the gastrointestinal tolerance of probiotic tablet containing Saccharomyces boular...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis
2020
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/30455/1/azhar2020.pdf |