Electrospinning for tissue engineering applications
Tissue engineering makes use of the principles of medicine, biology and engineering and integrates them into the design of biological substitutes to restore, maintain and improve the functions of tissue. To fabricate a functional tissue, the engineered structures have to be able to mimic the extrace...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/30852/1/Progress%20Mater%20Science_2020.pdf |
| _version_ | 1825813758192123904 |
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| author | Rahmati, Maryam Mills, David K. Urbanska, Aleksandra M. Venugopal, Jayarama Reddy Ramakrishna, Seeram Mozafari, Masoud Mohammad Reza, Saeb |
| author_facet | Rahmati, Maryam Mills, David K. Urbanska, Aleksandra M. Venugopal, Jayarama Reddy Ramakrishna, Seeram Mozafari, Masoud Mohammad Reza, Saeb |
| author_sort | Rahmati, Maryam |
| collection | UMP |
| description | Tissue engineering makes use of the principles of medicine, biology and engineering and integrates them into the design of biological substitutes to restore, maintain and improve the functions of tissue. To fabricate a functional tissue, the engineered structures have to be able to mimic the extracellular matrix (ECM), provide the tissue with oxygen and nutrient circulation as well as remove metabolic wastes in the period of tissue regeneration. Continued efforts have been made in order to fabricate advanced functional three-dimensional scaffolds for tissue engineering. Electrospinning has been recognized and served as one of the most useful techniques based on the resemblance between electrospun fibers and the native tissues. Over the past few decades, a bewildering variety of nanofibrous scaffolds have been developed for various biomedical applications, such as tissue regeneration and therapeutic agent delivery. The present review aims to provide with researchers an in-depth understanding of the promising role and the practical region of applicability of electrospinning in tissue engineering and regenerative medicine by highlighting the outcomes of the most recent studies performed in this field. We address the current strategies used for improving the physicochemical interactions between the cells and the nanofibrous surface. We also discuss the progress and challenges associated with the use of electrospinning for tissue engineering and regenerative medicine applications. |
| first_indexed | 2024-03-06T12:48:47Z |
| format | Article |
| id | UMPir30852 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T12:48:47Z |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | UMPir308522021-09-23T07:12:55Z http://umpir.ump.edu.my/id/eprint/30852/ Electrospinning for tissue engineering applications Rahmati, Maryam Mills, David K. Urbanska, Aleksandra M. Venugopal, Jayarama Reddy Ramakrishna, Seeram Mozafari, Masoud Mohammad Reza, Saeb R Medicine (General) Tissue engineering makes use of the principles of medicine, biology and engineering and integrates them into the design of biological substitutes to restore, maintain and improve the functions of tissue. To fabricate a functional tissue, the engineered structures have to be able to mimic the extracellular matrix (ECM), provide the tissue with oxygen and nutrient circulation as well as remove metabolic wastes in the period of tissue regeneration. Continued efforts have been made in order to fabricate advanced functional three-dimensional scaffolds for tissue engineering. Electrospinning has been recognized and served as one of the most useful techniques based on the resemblance between electrospun fibers and the native tissues. Over the past few decades, a bewildering variety of nanofibrous scaffolds have been developed for various biomedical applications, such as tissue regeneration and therapeutic agent delivery. The present review aims to provide with researchers an in-depth understanding of the promising role and the practical region of applicability of electrospinning in tissue engineering and regenerative medicine by highlighting the outcomes of the most recent studies performed in this field. We address the current strategies used for improving the physicochemical interactions between the cells and the nanofibrous surface. We also discuss the progress and challenges associated with the use of electrospinning for tissue engineering and regenerative medicine applications. Elsevier 2021-04-13 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/30852/1/Progress%20Mater%20Science_2020.pdf Rahmati, Maryam and Mills, David K. and Urbanska, Aleksandra M. and Venugopal, Jayarama Reddy and Ramakrishna, Seeram and Mozafari, Masoud and Mohammad Reza, Saeb (2021) Electrospinning for tissue engineering applications. Progress in Materials Science, 117. pp. 1-39. ISSN 0079-6425. (Published) https://doi.org/10.1016/j.pmatsci.2020.100721 https://doi.org/10.1016/j.pmatsci.2020.100721 |
| spellingShingle | R Medicine (General) Rahmati, Maryam Mills, David K. Urbanska, Aleksandra M. Venugopal, Jayarama Reddy Ramakrishna, Seeram Mozafari, Masoud Mohammad Reza, Saeb Electrospinning for tissue engineering applications |
| title | Electrospinning for tissue engineering applications |
| title_full | Electrospinning for tissue engineering applications |
| title_fullStr | Electrospinning for tissue engineering applications |
| title_full_unstemmed | Electrospinning for tissue engineering applications |
| title_short | Electrospinning for tissue engineering applications |
| title_sort | electrospinning for tissue engineering applications |
| topic | R Medicine (General) |
| url | http://umpir.ump.edu.my/id/eprint/30852/1/Progress%20Mater%20Science_2020.pdf |
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