Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb

AbstractThis paper investigates the optimum processing conditions of microwave assisted extraction (MAE) of anthraquinone (aloe emodin, AE) and flavonoids (kaempferol 3-gentiobioside, K3G and kaempferol, KA) from Senna alata (L.) Roxb. The kinetic study indicates that MAE showed a greater extraction...

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Main Authors: Yeong, Yi Ling, Pang, Sook Fun, Putranto, Aditya, Jolius, Gimbun
Format: Article
Language:English
Published: Taylor & Francis 2021
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/31920/1/Yeong%202021.pdf
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author Yeong, Yi Ling
Pang, Sook Fun
Putranto, Aditya
Jolius, Gimbun
author_facet Yeong, Yi Ling
Pang, Sook Fun
Putranto, Aditya
Jolius, Gimbun
author_sort Yeong, Yi Ling
collection UMP
description AbstractThis paper investigates the optimum processing conditions of microwave assisted extraction (MAE) of anthraquinone (aloe emodin, AE) and flavonoids (kaempferol 3-gentiobioside, K3G and kaempferol, KA) from Senna alata (L.) Roxb. The kinetic study indicates that MAE showed a greater extraction rate, compared to ultrasonic-assisted and maceration, due to the enhanced power which altered the leaf microstructures. The optimisation was undertaken using one-factor-at-a-time, two-level factorial design and central composite design were used to maximise the yield of the target compounds. The optimum yield of K3G (4.27 mg/g DW), KA (8.54 mg/g DW) and AE (0.86 mg/g DW) was obtained at 90.5% ethanol, microwave power of 18.6 W/mL with a desirability of 0.82. In addition, the yield of K3G and KA is correlated positively with the antioxidant activity.
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spelling UMPir319202021-09-17T04:49:12Z http://umpir.ump.edu.my/id/eprint/31920/ Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb Yeong, Yi Ling Pang, Sook Fun Putranto, Aditya Jolius, Gimbun TP Chemical technology AbstractThis paper investigates the optimum processing conditions of microwave assisted extraction (MAE) of anthraquinone (aloe emodin, AE) and flavonoids (kaempferol 3-gentiobioside, K3G and kaempferol, KA) from Senna alata (L.) Roxb. The kinetic study indicates that MAE showed a greater extraction rate, compared to ultrasonic-assisted and maceration, due to the enhanced power which altered the leaf microstructures. The optimisation was undertaken using one-factor-at-a-time, two-level factorial design and central composite design were used to maximise the yield of the target compounds. The optimum yield of K3G (4.27 mg/g DW), KA (8.54 mg/g DW) and AE (0.86 mg/g DW) was obtained at 90.5% ethanol, microwave power of 18.6 W/mL with a desirability of 0.82. In addition, the yield of K3G and KA is correlated positively with the antioxidant activity. Taylor & Francis 2021-02-04 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/31920/1/Yeong%202021.pdf Yeong, Yi Ling and Pang, Sook Fun and Putranto, Aditya and Jolius, Gimbun (2021) Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb. Natural Product Research. pp. 1-5. ISSN 1478-6427. (In Press / Online First) (In Press / Online First) https://doi.org/10.1080/14786419.2021.1881096 https://doi.org/10.1080/14786419.2021.1881096
spellingShingle TP Chemical technology
Yeong, Yi Ling
Pang, Sook Fun
Putranto, Aditya
Jolius, Gimbun
Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb
title Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb
title_full Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb
title_fullStr Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb
title_full_unstemmed Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb
title_short Optimisation of microwave-assisted extraction (MAE) of anthraquinone and flavonoids from Senna alata (L.) Roxb
title_sort optimisation of microwave assisted extraction mae of anthraquinone and flavonoids from senna alata l roxb
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/31920/1/Yeong%202021.pdf
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