Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties
Plant-derived substances have recently attracted the great interest towards their versatile application, as medicinal plants used in traditional and modern medicine. The aim of the current study was to investigate the antioxidant activity of Ziziphus mauritiana (ZM) leaves extract followed with the...
| Main Authors: | , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
Penerbit Universiti Malaysia Pahang
2021
|
| 主题: | |
| 在线阅读: | http://umpir.ump.edu.my/id/eprint/36619/1/IJETS%20ZM%20cream.pdf |
| _version_ | 1825814783586205696 |
|---|---|
| author | Mokhtar, Siti Umairah Murugan, Ashviny Che Awang, Che Syakira |
| author_facet | Mokhtar, Siti Umairah Murugan, Ashviny Che Awang, Che Syakira |
| author_sort | Mokhtar, Siti Umairah |
| collection | UMP |
| description | Plant-derived substances have recently attracted the great interest towards their versatile application, as medicinal plants used in traditional and modern medicine. The aim of the current study was to investigate the antioxidant activity of Ziziphus mauritiana (ZM) leaves extract followed with the formulation of herbal creams based on ZM methanolic extract then evaluate the physical characteristic and stability of the creams. After the methanolic extract was obtained by
using Soxhlet extraction, the extract was assessed for its antioxidant activity by using 2,2- Diphenyl�1-picrylhydrazyl (DPPH) assay which showed IC50 value of the ZM extract is 10.57 µg/ml, while IC50 value for ascorbic acid is 4.19 µg/ml. Four formulations of water in oil (w/o) emulsion based
cream in range of 39.9 – 44.9% w/o were formulated based on ZM leaves extract which are F1, F2, F3 and F4. Several physical properties were evaluated such as organoleptic, pH, viscosity, homogeneity, washability and emmolliency which proved that all formulations have good homogeneity, non greasy and under suitable pH and viscosity. Based on thermal stability test (45 °C ± 70 % RH, for 48 hours), it showed that F4 is not stable at high temperature compared to other
formulations. Thus, the present study indicated that Ziziphus mauritiana leaves extract has great potential for personal care product development due to its antioxidant property. |
| first_indexed | 2024-03-06T13:03:41Z |
| format | Article |
| id | UMPir36619 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T13:03:41Z |
| publishDate | 2021 |
| publisher | Penerbit Universiti Malaysia Pahang |
| record_format | dspace |
| spelling | UMPir366192023-02-22T01:27:30Z http://umpir.ump.edu.my/id/eprint/36619/ Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties Mokhtar, Siti Umairah Murugan, Ashviny Che Awang, Che Syakira QD Chemistry TP Chemical technology Plant-derived substances have recently attracted the great interest towards their versatile application, as medicinal plants used in traditional and modern medicine. The aim of the current study was to investigate the antioxidant activity of Ziziphus mauritiana (ZM) leaves extract followed with the formulation of herbal creams based on ZM methanolic extract then evaluate the physical characteristic and stability of the creams. After the methanolic extract was obtained by using Soxhlet extraction, the extract was assessed for its antioxidant activity by using 2,2- Diphenyl�1-picrylhydrazyl (DPPH) assay which showed IC50 value of the ZM extract is 10.57 µg/ml, while IC50 value for ascorbic acid is 4.19 µg/ml. Four formulations of water in oil (w/o) emulsion based cream in range of 39.9 – 44.9% w/o were formulated based on ZM leaves extract which are F1, F2, F3 and F4. Several physical properties were evaluated such as organoleptic, pH, viscosity, homogeneity, washability and emmolliency which proved that all formulations have good homogeneity, non greasy and under suitable pH and viscosity. Based on thermal stability test (45 °C ± 70 % RH, for 48 hours), it showed that F4 is not stable at high temperature compared to other formulations. Thus, the present study indicated that Ziziphus mauritiana leaves extract has great potential for personal care product development due to its antioxidant property. Penerbit Universiti Malaysia Pahang 2021 Article PeerReviewed pdf en cc_by_4 http://umpir.ump.edu.my/id/eprint/36619/1/IJETS%20ZM%20cream.pdf Mokhtar, Siti Umairah and Murugan, Ashviny and Che Awang, Che Syakira (2021) Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties. International Journal of Engineering Technology And Sciences (IJETS), 8 (1). pp. 34-39. ISSN 2289-697X. (Published) https://doi.org/10.15282/ijets.8.1.2021.1005 https://doi.org/10.15282/ijets.8.1.2021.1005 |
| spellingShingle | QD Chemistry TP Chemical technology Mokhtar, Siti Umairah Murugan, Ashviny Che Awang, Che Syakira Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties |
| title | Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties |
| title_full | Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties |
| title_fullStr | Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties |
| title_full_unstemmed | Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties |
| title_short | Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on its physicochemical properties |
| title_sort | formulation of herbal cream based on ziziphus mauritiana leaves extract and evaluation on its physicochemical properties |
| topic | QD Chemistry TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/36619/1/IJETS%20ZM%20cream.pdf |
| work_keys_str_mv | AT mokhtarsitiumairah formulationofherbalcreambasedonziziphusmauritianaleavesextractandevaluationonitsphysicochemicalproperties AT muruganashviny formulationofherbalcreambasedonziziphusmauritianaleavesextractandevaluationonitsphysicochemicalproperties AT cheawangchesyakira formulationofherbalcreambasedonziziphusmauritianaleavesextractandevaluationonitsphysicochemicalproperties |