Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria
Antimicrobial resistance has become the major threat to the health worldwide. It has lead to the ineffective impact of the ability of the substance or antibiotics to kill the bacteria. Therefore, there is a need to find a new alternative to overcome the problem by using natural products. In this stu...
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| Format: | Article |
| Language: | English |
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Penerbit Akademia Baru
2022
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| Online Access: | http://umpir.ump.edu.my/id/eprint/37068/1/Synergism%20%20effect%20of%20Murraya%20%20koneigii%20and%20Piper%20%20betleleavesextractson%20antibacterialactivity%20against%20Gram%20Positive%20bacteria.pdf |
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| author | Putri Shareen, Rosman Syarmilla Ezza, Ismail Mohd Khairul, Bahri Nur Syazdiyana, Mohd Azmali Tan, Suat Hian |
| author_facet | Putri Shareen, Rosman Syarmilla Ezza, Ismail Mohd Khairul, Bahri Nur Syazdiyana, Mohd Azmali Tan, Suat Hian |
| author_sort | Putri Shareen, Rosman |
| collection | UMP |
| description | Antimicrobial resistance has become the major threat to the health worldwide. It has lead to the ineffective impact of the ability of the substance or antibiotics to kill the bacteria. Therefore, there is a need to find a new alternative to overcome the problem by using natural products. In this study Piper betle (P. betle ) and Murraya koenigii (M. koenigii) leaf extracts were used to measure their synergism effect towards antimicrobial treatments. Previous study has shown that both plants has shown their ability in inhibiting the growth of bacteria separately. Three different concentration ratios of the synergised leaf extracts were used with 1:1(P.betle:M. koenigii) ratios, 2:1 (P.betle:M. koenigii) ratios and 1:2 (P.betle:M.koenigii) ratios. The synergised leaf extracts was at the highest inhibition zone with combination of 2:1 ratio of P.betle and M. koenigii with 22.6mm. However, it does not have the greater inhibition ability as compared to the P.betle leaf extract with 28.1mm. Therefore, from the study, antagonism effect was discovered when both plant extracts were combined. |
| first_indexed | 2024-03-06T13:04:55Z |
| format | Article |
| id | UMPir37068 |
| institution | Universiti Malaysia Pahang |
| language | English |
| last_indexed | 2024-03-06T13:04:55Z |
| publishDate | 2022 |
| publisher | Penerbit Akademia Baru |
| record_format | dspace |
| spelling | UMPir370682023-03-09T03:47:49Z http://umpir.ump.edu.my/id/eprint/37068/ Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria Putri Shareen, Rosman Syarmilla Ezza, Ismail Mohd Khairul, Bahri Nur Syazdiyana, Mohd Azmali Tan, Suat Hian Q Science (General) QK Botany QR Microbiology S Agriculture (General) Antimicrobial resistance has become the major threat to the health worldwide. It has lead to the ineffective impact of the ability of the substance or antibiotics to kill the bacteria. Therefore, there is a need to find a new alternative to overcome the problem by using natural products. In this study Piper betle (P. betle ) and Murraya koenigii (M. koenigii) leaf extracts were used to measure their synergism effect towards antimicrobial treatments. Previous study has shown that both plants has shown their ability in inhibiting the growth of bacteria separately. Three different concentration ratios of the synergised leaf extracts were used with 1:1(P.betle:M. koenigii) ratios, 2:1 (P.betle:M. koenigii) ratios and 1:2 (P.betle:M.koenigii) ratios. The synergised leaf extracts was at the highest inhibition zone with combination of 2:1 ratio of P.betle and M. koenigii with 22.6mm. However, it does not have the greater inhibition ability as compared to the P.betle leaf extract with 28.1mm. Therefore, from the study, antagonism effect was discovered when both plant extracts were combined. Penerbit Akademia Baru 2022-10-31 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/37068/1/Synergism%20%20effect%20of%20Murraya%20%20koneigii%20and%20Piper%20%20betleleavesextractson%20antibacterialactivity%20against%20Gram%20Positive%20bacteria.pdf Putri Shareen, Rosman and Syarmilla Ezza, Ismail and Mohd Khairul, Bahri and Nur Syazdiyana, Mohd Azmali and Tan, Suat Hian (2022) Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria. Journal of Advanced Research in Applied Sciences and Engineering Technology, 28 (2). pp. 311-317. ISSN 2462-1943. (Published) http://doi.org/10.37934/araset.28.2.311317 http://doi.org/10.37934/araset.28.2.311317 |
| spellingShingle | Q Science (General) QK Botany QR Microbiology S Agriculture (General) Putri Shareen, Rosman Syarmilla Ezza, Ismail Mohd Khairul, Bahri Nur Syazdiyana, Mohd Azmali Tan, Suat Hian Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria |
| title | Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria |
| title_full | Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria |
| title_fullStr | Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria |
| title_full_unstemmed | Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria |
| title_short | Synergism effect of Murraya koneigii and Piper betle leaves extracts on antibacterial activity against Gram Positive bacteria |
| title_sort | synergism effect of murraya koneigii and piper betle leaves extracts on antibacterial activity against gram positive bacteria |
| topic | Q Science (General) QK Botany QR Microbiology S Agriculture (General) |
| url | http://umpir.ump.edu.my/id/eprint/37068/1/Synergism%20%20effect%20of%20Murraya%20%20koneigii%20and%20Piper%20%20betleleavesextractson%20antibacterialactivity%20against%20Gram%20Positive%20bacteria.pdf |
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