Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review
Biopolymers, especially polysaccharides and proteins, are the promising green replacement for petroleum based polymers. Due to their innate properties, they are effectively used in biomedical applications, especially tissue engineering, wound healing, and drug delivery. The fibrous morphology of bio...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English English |
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Elsevier Ltd
2023
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| Online Access: | http://umpir.ump.edu.my/id/eprint/38627/1/Current%20issues%20and%20potential%20solutions%20for%20the%20electrospinning.pdf http://umpir.ump.edu.my/id/eprint/38627/2/R3-%20Current%20issues%20and%20potential%20solutions%20for%20the%20electrospinning%20of%20major%20polysaccharides%20and%20proteins%20A%20review.pdf |
| _version_ | 1825815146107240448 |
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| author | Syed, Murtaza Haider Rahman Khan, Md. Maksudur Mohd Zahari, Mior Ahmad Khushairi Beg, Mohammad Dalour Hossen Abdullah, Norhayati |
| author_facet | Syed, Murtaza Haider Rahman Khan, Md. Maksudur Mohd Zahari, Mior Ahmad Khushairi Beg, Mohammad Dalour Hossen Abdullah, Norhayati |
| author_sort | Syed, Murtaza Haider |
| collection | UMP |
| description | Biopolymers, especially polysaccharides and proteins, are the promising green replacement for petroleum based polymers. Due to their innate properties, they are effectively used in biomedical applications, especially tissue engineering, wound healing, and drug delivery. The fibrous morphology of biopolymers is essentially required for the effectiveness in these biomedical applications. Electrospinning (ES) is the most advanced and robust method to fabricate nanofibers (NFs) and provides a complete solution to the conventional methods issues. However, the major issues regarding fabricating polysaccharides and protein nanofibers using ES include poor electrospinnability, lack of desired fundamental properties for a specific application by a single biopolymer, and insolubility among common solvents. The current review provides the main strategies for effective electrospinning of the major biopolymers. The key strategies include blending major biopolymers with suitable biopolymers and optimizing the solvent system. A systematic literature review was done to provide the optimized solvent system of the major biopolymers along with their best possible biopolymeric blend for ES. The review also highlights the fundamental issues with the commercialization of ES based biomedical products and provides future directions to improve the fabrication of biopolymeric nanofibers. |
| first_indexed | 2024-03-06T13:09:05Z |
| format | Article |
| id | UMPir38627 |
| institution | Universiti Malaysia Pahang |
| language | English English |
| last_indexed | 2024-03-06T13:09:05Z |
| publishDate | 2023 |
| publisher | Elsevier Ltd |
| record_format | dspace |
| spelling | UMPir386272023-09-13T05:34:20Z http://umpir.ump.edu.my/id/eprint/38627/ Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review Syed, Murtaza Haider Rahman Khan, Md. Maksudur Mohd Zahari, Mior Ahmad Khushairi Beg, Mohammad Dalour Hossen Abdullah, Norhayati QD Chemistry TP Chemical technology Biopolymers, especially polysaccharides and proteins, are the promising green replacement for petroleum based polymers. Due to their innate properties, they are effectively used in biomedical applications, especially tissue engineering, wound healing, and drug delivery. The fibrous morphology of biopolymers is essentially required for the effectiveness in these biomedical applications. Electrospinning (ES) is the most advanced and robust method to fabricate nanofibers (NFs) and provides a complete solution to the conventional methods issues. However, the major issues regarding fabricating polysaccharides and protein nanofibers using ES include poor electrospinnability, lack of desired fundamental properties for a specific application by a single biopolymer, and insolubility among common solvents. The current review provides the main strategies for effective electrospinning of the major biopolymers. The key strategies include blending major biopolymers with suitable biopolymers and optimizing the solvent system. A systematic literature review was done to provide the optimized solvent system of the major biopolymers along with their best possible biopolymeric blend for ES. The review also highlights the fundamental issues with the commercialization of ES based biomedical products and provides future directions to improve the fabrication of biopolymeric nanofibers. Elsevier Ltd 2023 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/38627/1/Current%20issues%20and%20potential%20solutions%20for%20the%20electrospinning.pdf pdf en http://umpir.ump.edu.my/id/eprint/38627/2/R3-%20Current%20issues%20and%20potential%20solutions%20for%20the%20electrospinning%20of%20major%20polysaccharides%20and%20proteins%20A%20review.pdf Syed, Murtaza Haider and Rahman Khan, Md. Maksudur and Mohd Zahari, Mior Ahmad Khushairi and Beg, Mohammad Dalour Hossen and Abdullah, Norhayati (2023) Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review. International Journal of Biological Macromolecules, 253 Part 2 (126735). ISSN 0141-8130. (Published) https://doi.org/10.1016/j.ijbiomac.2023.126735 10.1016/j.ijbiomac.2023.126735 |
| spellingShingle | QD Chemistry TP Chemical technology Syed, Murtaza Haider Rahman Khan, Md. Maksudur Mohd Zahari, Mior Ahmad Khushairi Beg, Mohammad Dalour Hossen Abdullah, Norhayati Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review |
| title | Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review |
| title_full | Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review |
| title_fullStr | Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review |
| title_full_unstemmed | Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review |
| title_short | Current issues and potential solutions for the electrospinning of major polysaccharides and proteins: A review |
| title_sort | current issues and potential solutions for the electrospinning of major polysaccharides and proteins a review |
| topic | QD Chemistry TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/38627/1/Current%20issues%20and%20potential%20solutions%20for%20the%20electrospinning.pdf http://umpir.ump.edu.my/id/eprint/38627/2/R3-%20Current%20issues%20and%20potential%20solutions%20for%20the%20electrospinning%20of%20major%20polysaccharides%20and%20proteins%20A%20review.pdf |
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