Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves
Combretum Indicum (CI), which contains numerous bioactive compounds, has been used in traditional medicine for a variety of reasons, including the treatment of skin conditions. This study investigates the antioxidant and anti-tyrosinase activities of CI leaves extracted using different surfactants (...
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| Format: | Conference or Workshop Item |
| Language: | English English |
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Elsevier Ltd
2024
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| Online Access: | http://umpir.ump.edu.my/id/eprint/39322/1/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves%20%28intro%29.pdf http://umpir.ump.edu.my/id/eprint/39322/2/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves.pdf |
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| author | Thanaseelan, Tanesha D. Nurul, Hidayu Nurul, Sahirah Rajaletchumy, Veloo Kutty |
| author_facet | Thanaseelan, Tanesha D. Nurul, Hidayu Nurul, Sahirah Rajaletchumy, Veloo Kutty |
| author_sort | Thanaseelan, Tanesha |
| collection | UMP |
| description | Combretum Indicum (CI), which contains numerous bioactive compounds, has been used in traditional medicine for a variety of reasons, including the treatment of skin conditions. This study investigates the antioxidant and anti-tyrosinase activities of CI leaves extracted using different surfactants (Triton X-100 and Vitamin E TPGS) at concentrations of 1%, 2%, and 3%, as well as various alcohol solvents (acetone, methanol, and ethanol) at concentrations of 50%, 70%, and 90%. The antioxidant activity of the extracts has been evaluated using Total Phenolic Content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH), while the anti-tyrosinase activity was assessed through a mushroom tyrosinase inhibition assay. Prior to analysis, CI leaves had been macerated, extracted, and freeze-dried. The research established that ethanol at a concentration of 50% is the optimum solvent to extract CI leaves, as it demonstrated good antioxidant and anti-tyrosinase action with a high percentage of yield and total phenolic content. As a result, the outcomes of this study contribute to a better understanding of the potential applications of CI leaf extract in cosmetics, notably in the treatment of oxidative stress and hyperpigmentation. Further study and development in this field could lead to the creation of effective and natural cosmetic products produced from CI leaves that have antioxidant and anti-tyrosinase effects. |
| first_indexed | 2024-03-06T13:11:04Z |
| format | Conference or Workshop Item |
| id | UMPir39322 |
| institution | Universiti Malaysia Pahang |
| language | English English |
| last_indexed | 2025-02-19T02:37:23Z |
| publishDate | 2024 |
| publisher | Elsevier Ltd |
| record_format | dspace |
| spelling | UMPir393222025-01-22T08:23:23Z http://umpir.ump.edu.my/id/eprint/39322/ Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves Thanaseelan, Tanesha D. Nurul, Hidayu Nurul, Sahirah Rajaletchumy, Veloo Kutty QD Chemistry T Technology (General) TP Chemical technology Combretum Indicum (CI), which contains numerous bioactive compounds, has been used in traditional medicine for a variety of reasons, including the treatment of skin conditions. This study investigates the antioxidant and anti-tyrosinase activities of CI leaves extracted using different surfactants (Triton X-100 and Vitamin E TPGS) at concentrations of 1%, 2%, and 3%, as well as various alcohol solvents (acetone, methanol, and ethanol) at concentrations of 50%, 70%, and 90%. The antioxidant activity of the extracts has been evaluated using Total Phenolic Content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH), while the anti-tyrosinase activity was assessed through a mushroom tyrosinase inhibition assay. Prior to analysis, CI leaves had been macerated, extracted, and freeze-dried. The research established that ethanol at a concentration of 50% is the optimum solvent to extract CI leaves, as it demonstrated good antioxidant and anti-tyrosinase action with a high percentage of yield and total phenolic content. As a result, the outcomes of this study contribute to a better understanding of the potential applications of CI leaf extract in cosmetics, notably in the treatment of oxidative stress and hyperpigmentation. Further study and development in this field could lead to the creation of effective and natural cosmetic products produced from CI leaves that have antioxidant and anti-tyrosinase effects. Elsevier Ltd 2024 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/39322/1/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves%20%28intro%29.pdf pdf en http://umpir.ump.edu.my/id/eprint/39322/2/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves.pdf Thanaseelan, Tanesha and D. Nurul, Hidayu and Nurul, Sahirah and Rajaletchumy, Veloo Kutty (2024) Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves. In: Materials Today: Proceedings. Materials Today: Proceedings; 6th National Conference for Postgraduate Research (NCON-PGR 2022) , 15 November 2022 , Virtual, Online. pp. 224-230., 107. ISSN 2214-7853 (Published) https://doi.org/10.1016/j.matpr.2023.10.077 |
| spellingShingle | QD Chemistry T Technology (General) TP Chemical technology Thanaseelan, Tanesha D. Nurul, Hidayu Nurul, Sahirah Rajaletchumy, Veloo Kutty Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves |
| title | Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves |
| title_full | Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves |
| title_fullStr | Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves |
| title_full_unstemmed | Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves |
| title_short | Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted Combretum Indicum leaves |
| title_sort | evaluation of antioxidant and anti tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves |
| topic | QD Chemistry T Technology (General) TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/39322/1/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves%20%28intro%29.pdf http://umpir.ump.edu.my/id/eprint/39322/2/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves.pdf |
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