Virtual screening, molecular docking, molecular dynamics, and MM-GBSA approaches identify prospective fructose-1,6-bisphosphatase inhibitors from pineapple for diabetes management
Diabetes affects millions globally and poses treatment challenges. Targeting the enzyme fructose-1,6-bisphosphatase (FBPase) in gluconeogenesis and exploring plant-based therapies offer potential solutions for improving diabetes management while supporting sustainability and medicinal advancements....
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Taylor & Francis
2023
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/40547/2/Hossain%20et%20al.%202023.%20Virtual%20screening%20molecular%20docking%20molecular%20dynamics%20and%20MM-GBSA%20approaches%20identify%20prospective%20fructose-1%206-bisphosphatase%20inhibitors%20from%20pine.pdf http://umpir.ump.edu.my/id/eprint/40547/3/Virtual%20screening%20molecular%20docking%20molecular%20dynamics%20and%20MM-GBSA%20approaches%20identify%20prospective%20fructose-1%206-bisphosphatase%20inhibitors%20from%20pine.pdf |