Advancement of lignin into bioactive compounds through selective organic synthesis methods
The conversion of lignin into bioactive compounds through selective organic synthesis methods represents a promising frontier in the pursuit of sustainable raw materials and green chemistry. This review explores the versatility of lignin-derived bioactive compounds, ranging from their application in...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English English |
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Elsevier Ltd
2024
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| Online Access: | http://umpir.ump.edu.my/id/eprint/42386/1/Advancement%20of%20lignin%20into%20bioactive%20compounds_ABST.pdf http://umpir.ump.edu.my/id/eprint/42386/2/Advancement%20of%20lignin%20into%20bioactive%20compounds.pdf |
| _version_ | 1811138590216814592 |
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| author | Jadhav, Pramod Bhuyar, Prakash Izan Izwan, Misnon Mohd Hasbi, Ab Rahim Rasidi, Roslan |
| author_facet | Jadhav, Pramod Bhuyar, Prakash Izan Izwan, Misnon Mohd Hasbi, Ab Rahim Rasidi, Roslan |
| author_sort | Jadhav, Pramod |
| collection | UMP |
| description | The conversion of lignin into bioactive compounds through selective organic synthesis methods represents a promising frontier in the pursuit of sustainable raw materials and green chemistry. This review explores the versatility of lignin-derived bioactive compounds, ranging from their application in drug discovery to their role in the development of biodegradable materials. Despite notable advancements, the synthesis routes and yields of highly bioactive molecules from lignin still require further exploration and improvement. This review provides an in-depth examination of the progress made in understanding the complex structure of lignin and developing innovative approaches to exploit its potential. Specifically, the types of lignins covered include softwood Kraft lignin, hardwood organosolv lignin, and soda lignin. This work is divided into three parts: first, the transformation of lignin into bioactive molecules with chemically active centres and functionalised hydroxyl groups through depolymerisation; second, kinetic modelling techniques essential for understanding the chemical kinetics of lignin and enabling significant scaling up in the conversion of organic molecules; third, efficient catalytic pathways for synthesising molecules with anticancer and antibacterial properties. In conclusion, this comprehensive review spurs further investigations into lignin-derived bioactive compounds, their applications, and the advancement of sustainable processes. |
| first_indexed | 2024-09-25T03:52:36Z |
| format | Article |
| id | UMPir42386 |
| institution | Universiti Malaysia Pahang |
| language | English English |
| last_indexed | 2024-09-25T03:52:36Z |
| publishDate | 2024 |
| publisher | Elsevier Ltd |
| record_format | dspace |
| spelling | UMPir423862024-08-16T08:22:47Z http://umpir.ump.edu.my/id/eprint/42386/ Advancement of lignin into bioactive compounds through selective organic synthesis methods Jadhav, Pramod Bhuyar, Prakash Izan Izwan, Misnon Mohd Hasbi, Ab Rahim Rasidi, Roslan Q Science (General) TP Chemical technology The conversion of lignin into bioactive compounds through selective organic synthesis methods represents a promising frontier in the pursuit of sustainable raw materials and green chemistry. This review explores the versatility of lignin-derived bioactive compounds, ranging from their application in drug discovery to their role in the development of biodegradable materials. Despite notable advancements, the synthesis routes and yields of highly bioactive molecules from lignin still require further exploration and improvement. This review provides an in-depth examination of the progress made in understanding the complex structure of lignin and developing innovative approaches to exploit its potential. Specifically, the types of lignins covered include softwood Kraft lignin, hardwood organosolv lignin, and soda lignin. This work is divided into three parts: first, the transformation of lignin into bioactive molecules with chemically active centres and functionalised hydroxyl groups through depolymerisation; second, kinetic modelling techniques essential for understanding the chemical kinetics of lignin and enabling significant scaling up in the conversion of organic molecules; third, efficient catalytic pathways for synthesising molecules with anticancer and antibacterial properties. In conclusion, this comprehensive review spurs further investigations into lignin-derived bioactive compounds, their applications, and the advancement of sustainable processes. Elsevier Ltd 2024-07 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42386/1/Advancement%20of%20lignin%20into%20bioactive%20compounds_ABST.pdf pdf en http://umpir.ump.edu.my/id/eprint/42386/2/Advancement%20of%20lignin%20into%20bioactive%20compounds.pdf Jadhav, Pramod and Bhuyar, Prakash and Izan Izwan, Misnon and Mohd Hasbi, Ab Rahim and Rasidi, Roslan (2024) Advancement of lignin into bioactive compounds through selective organic synthesis methods. International Journal of Biological Macromolecules, 276 (134061). pp. 1-10. ISSN 0141-8130. (Published) https://doi.org/10.1016/j.ijbiomac.2024.134061 https://doi.org/10.1016/j.ijbiomac.2024.134061 |
| spellingShingle | Q Science (General) TP Chemical technology Jadhav, Pramod Bhuyar, Prakash Izan Izwan, Misnon Mohd Hasbi, Ab Rahim Rasidi, Roslan Advancement of lignin into bioactive compounds through selective organic synthesis methods |
| title | Advancement of lignin into bioactive compounds through selective organic synthesis methods |
| title_full | Advancement of lignin into bioactive compounds through selective organic synthesis methods |
| title_fullStr | Advancement of lignin into bioactive compounds through selective organic synthesis methods |
| title_full_unstemmed | Advancement of lignin into bioactive compounds through selective organic synthesis methods |
| title_short | Advancement of lignin into bioactive compounds through selective organic synthesis methods |
| title_sort | advancement of lignin into bioactive compounds through selective organic synthesis methods |
| topic | Q Science (General) TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/42386/1/Advancement%20of%20lignin%20into%20bioactive%20compounds_ABST.pdf http://umpir.ump.edu.my/id/eprint/42386/2/Advancement%20of%20lignin%20into%20bioactive%20compounds.pdf |
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